Terms: = Sarcomas AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
20 results:
1. E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways.
Huang TT; Chen CM; Lin SS; Lan YW; Cheng HC; Choo KB; Wang CC; Huang TH; Chong KY
Int J Mol Sci; 2023 May; 24(11):. PubMed ID: 37298555
[TBL] [Abstract] [Full Text] [Related]
2. Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.
Samarina N; Ssebyatika G; Tikla T; Waldmann JY; Abere B; Nanna V; Marasco M; Carlomagno T; Krey T; Schulz TF
PLoS Pathog; 2021 Jun; 17(6):e1009635. PubMed ID: 34143834
[TBL] [Abstract] [Full Text] [Related]
3. Molecular subtypes in canine hemangiosarcoma reveal similarities with human angiosarcoma.
Wang G; Wu M; Durham AC; Radaelli E; Mason NJ; Xu X; Roth DB
PLoS One; 2020; 15(3):e0229728. PubMed ID: 32210430
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4. Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication.
Abere B; Samarina N; Gramolelli S; Rückert J; Gerold G; Pich A; Schulz TF
J Virol; 2018 Sep; 92(17):. PubMed ID: 29950425
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5. Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors.
Kostas M; Haugsten EM; Zhen Y; Sørensen V; Szybowska P; Fiorito E; Lorenz S; Jones N; de Souza GA; Wiedlocha A; Wesche J
Mol Cell Proteomics; 2018 May; 17(5):850-870. PubMed ID: 29371290
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6. The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
Abere B; Mamo TM; Hartmann S; Samarina N; Hage E; Rückert J; Hotop SK; Büsche G; Schulz TF
PLoS Pathog; 2017 Sep; 13(9):e1006639. PubMed ID: 28938025
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7. Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of plcg1, KDR, MYC, and FLT4 Gene Alterations.
Huang SC; Zhang L; Sung YS; Chen CL; Kao YC; Agaram NP; Singer S; Tap WD; D'Angelo S; Antonescu CR
Am J Surg Pathol; 2016 May; 40(5):645-55. PubMed ID: 26735859
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8. Phospholipase C gamma 1 (plcg1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma.
Prenen H; Smeets D; Mazzone M; Lambrechts D; Sagaert X; Sciot R; Debiec-Rychter M
Oncotarget; 2015 Nov; 6(34):36418-25. PubMed ID: 26474454
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9. Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Murali R; Chandramohan R; Möller I; Scholz SL; Berger M; Huberman K; Viale A; Pirun M; Socci ND; Bouvier N; Bauer S; Artl M; Schilling B; Schimming T; Sucker A; Schwindenhammer B; Grabellus F; Speicher MR; Schaller J; Hillen U; Schadendorf D; Mentzel T; Cheng DT; Wiesner T; Griewank KG
Oncotarget; 2015 Nov; 6(34):36041-52. PubMed ID: 26440310
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10. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells.
Gramolelli S; Weidner-Glunde M; Abere B; Viejo-Borbolla A; Bala K; Rückert J; Kremmer E; Schulz TF
PLoS Pathog; 2015 Aug; 11(8):e1005105. PubMed ID: 26295810
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11. Gene expression profiling analysis of osteosarcoma cell lines.
Sun L; Li J; Yan B
Mol Med Rep; 2015 Sep; 12(3):4266-4272. PubMed ID: 26096802
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12. Structure and function of Gab2 and its role in cancer (Review).
Ding CB; Yu WN; Feng JH; Luo JM
Mol Med Rep; 2015 Sep; 12(3):4007-4014. PubMed ID: 26095858
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13. A recurrent activating plcg1 mutation in cardiac angiosarcomas increases apoptosis resistance and invasiveness of endothelial cells.
Kunze K; Spieker T; Gamerdinger U; Nau K; Berger J; Dreyer T; Sindermann JR; Hoffmeier A; Gattenlöhner S; Bräuninger A
Cancer Res; 2014 Nov; 74(21):6173-83. PubMed ID: 25252913
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14. Angiogenesis-related gene mutations drive a subset of angiosarcomas.
Cancer Discov; 2014 May; 4(5):OF18. PubMed ID: 24795022
[TBL] [Abstract] [Full Text] [Related]
15. Recurrent PTPRB and plcg1 mutations in angiosarcoma.
Behjati S; Tarpey PS; Sheldon H; Martincorena I; Van Loo P; Gundem G; Wedge DC; Ramakrishna M; Cooke SL; Pillay N; Vollan HKM; Papaemmanuil E; Koss H; Bunney TD; Hardy C; Joseph OR; Martin S; Mudie L; Butler A; Teague JW; Patil M; Steers G; Cao Y; Gumbs C; Ingram D; Lazar AJ; Little L; Mahadeshwar H; Protopopov A; Al Sannaa GA; Seth S; Song X; Tang J; Zhang J; Ravi V; Torres KE; Khatri B; Halai D; Roxanis I; Baumhoer D; Tirabosco R; Amary MF; Boshoff C; McDermott U; Katan M; Stratton MR; Futreal PA; Flanagan AM; Harris A; Campbell PJ
Nat Genet; 2014 Apr; 46(4):376-379. PubMed ID: 24633157
[TBL] [Abstract] [Full Text] [Related]
16. Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression.
Bala K; Bosco R; Gramolelli S; Haas DA; Kati S; Pietrek M; Hävemeier A; Yakushko Y; Singh VV; Dittrich-Breiholz O; Kracht M; Schulz TF
PLoS Pathog; 2012 Sep; 8(9):e1002927. PubMed ID: 23028325
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17. Identification of BRAF as a new interactor of PLCepsilon1, the protein mutated in nephrotic syndrome type 3.
Chaib H; Hoskins BE; Ashraf S; Goyal M; Wiggins RC; Hildebrandt F
Am J Physiol Renal Physiol; 2008 Jan; 294(1):F93-9. PubMed ID: 17942568
[TBL] [Abstract] [Full Text] [Related]
18. The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells.
Tassi I; Colonna M
J Immunol; 2005 Dec; 175(12):7996-8002. PubMed ID: 16339536
[TBL] [Abstract] [Full Text] [Related]
19. TGF-beta1 selectively suppresses PDGF receptor signaling pathways in MG-63 human osteosarcoma cell.
Hung LM; Tsai CH; Chen JK
Life Sci; 1997; 61(7):685-93. PubMed ID: 9252243
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20. Sequence similarity of phospholipase C with the non-catalytic region of src.
Stahl ML; Ferenz CR; Kelleher KL; Kriz RW; Knopf JL
Nature; 1988 Mar; 332(6161):269-72. PubMed ID: 2831461
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