BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND PRKAR1A, DKFZp779L0468, 5573, ENSG00000108946, PRKAR1, P10644, CNC1, PKR1, MGC17251, PPNAD1, TSE1, CNC, CAR AND Treatment
79 results:

  • 1. A high-content screen of FDA approved drugs to enhance car T cell function: ingenol-3-angelate improves B7-H3-car T cell activity by upregulating B7-H3 on the target cell surface via PKCα activation.
    Lee HW; O'Reilly C; Beckett AN; Currier DG; Chen T; DeRenzo C
    J Exp Clin Cancer Res; 2024 Apr; 43(1):97. PubMed ID: 38561833
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Protocol for a mixed-methods study to develop and feasibility test a digital system for the capture of patient-reported outcomes (PROs) in patients receiving chimeric antigen receptor T-cell (car-T) therapies (the PRO-car-T study).
    Hughes SE; McMullan C; Aiyegbusi OL; Shaw K; Kinsella F; Ferguson P; Khatsuria F; Burns D; Pyatt L; Ansell J; Chakera E; Richardson-Abraham J; Denniston AK; Davies EH; Craddock C; Calvert M
    BMJ Open; 2024 Mar; 14(3):e085392. PubMed ID: 38553074
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Chimeric antigen receptor T cells in the treatment of osteosarcoma (Review).
    Yu T; Jiang W; Wang Y; Zhou Y; Jiao J; Wu M
    Int J Oncol; 2024 Apr; 64(4):. PubMed ID: 38390935
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A novel approach to guide GD2-targeted therapy in pediatric tumors by PET and [
    Trautwein NF; Schwenck J; Seitz C; Seith F; Calderón E; von Beschwitz S; Singer S; Reischl G; Handgretinger R; Schäfer J; Lang P; Pichler BJ; Schulte JH; la Fougère C; Dittmann H
    Theranostics; 2024; 14(3):1212-1223. PubMed ID: 38323317
    [No Abstract]    [Full Text] [Related]  

  • 5. Histiocytic sarcoma following car T-cell therapy: a case report.
    An K; He Y; Tang Y; Gu X; Qian J; Li B
    Int J Hematol; 2024 Mar; 119(3):338-341. PubMed ID: 38294639
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Role of Immunotherapy in sarcomas.
    Dalal S; Shan KS; Thaw Dar NN; Hussein A; Ergle A
    Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38279265
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Current status and future challenges of car-T cell therapy for osteosarcoma.
    Li S; Zhang H; Shang G
    Front Immunol; 2023; 14():1290762. PubMed ID: 38187386
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The Future of HER2-Targeted treatment for Osteosarcoma: Lessons from the Negative Trastuzumab Deruxtecan Results.
    Nakano K
    Int J Mol Sci; 2023 Nov; 24(23):. PubMed ID: 38069146
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.
    Tian M; Wei JS; Shivaprasad N; Highfill SL; Gryder BE; Milewski D; Brown GT; Moses L; Song H; Wu JT; Azorsa P; Kumar J; Schneider D; Chou HC; Song YK; Rahmy A; Masih KE; Kim YY; Belyea B; Linardic CM; Dropulic B; Sullivan PM; Sorensen PH; Dimitrov DS; Maris JM; Mackall CL; Orentas RJ; Cheuk AT; Khan J
    Cell Rep Med; 2023 Oct; 4(10):101212. PubMed ID: 37774704
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. ErbB2 (HER2)-car-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma.
    Heim C; Moser LM; Kreyenberg H; Bonig HB; Tonn T; Wels WS; Gradhand E; Ullrich E; Meister MT; Koerkamp MG; Holstege FCP; Drost J; Klusmann JH; Bader P; Merker M; Rettinger E
    Front Immunol; 2023; 14():1228894. PubMed ID: 37662907
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Promise and Challenges of T Cell Immunotherapy for Osteosarcoma.
    Park JA; Cheung NV
    Int J Mol Sci; 2023 Aug; 24(15):. PubMed ID: 37569894
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. 4-1BB Targeting Immunotherapy: Mechanism, Antibodies, and Chimeric Antigen Receptor T.
    Shen X; Zhang R; Nie X; Yang Y; Hua Y; Lü P
    Cancer Biother Radiopharm; 2023 Sep; 38(7):431-444. PubMed ID: 37433196
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Targeting B7-H3-A Novel Strategy for the Design of Anticancer Agents for Extracranial Pediatric Solid Tumors treatment.
    Rasic P; Jeremic M; Jeremic R; Dusanovic Pjevic M; Rasic M; Djuricic SM; Milickovic M; Vukadin M; Mijovic T; Savic D
    Molecules; 2023 Apr; 28(8):. PubMed ID: 37110590
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. "I just wanted to speak to someone- and there was no one…": using Burden of treatment Theory to understand the impact of a novel ATMP on early recipients.
    Litchfield I; Calvert MJ; Kinsella F; Sungum N; Aiyegbusi OL
    Orphanet J Rare Dis; 2023 Apr; 18(1):86. PubMed ID: 37069697
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Switchable car T cell strategy against osteosarcoma.
    Hidalgo L; Somovilla-Crespo B; Garcia-Rodriguez P; Morales-Molina A; Rodriguez-Milla MA; Garcia-Castro J
    Cancer Immunol Immunother; 2023 Aug; 72(8):2623-2633. PubMed ID: 37062034
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Are targeted therapies or immunotherapies effective in metastatic pancreatic adenocarcinoma?
    Rémond MS; Pellat A; Brezault C; Dhooge M; Coriat R
    ESMO Open; 2022 Dec; 7(6):100638. PubMed ID: 36399952
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. B7-H3 targeted car-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo.
    Zhang Q; Zhang Z; Liu G; Li D; Gu Z; Zhang L; Pan Y; Cui X; Wang L; Liu G; Tian X; Zhang Z
    BMC Cancer; 2022 Nov; 22(1):1124. PubMed ID: 36320072
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. DLL3 as an Emerging Target for the treatment of Neuroendocrine Neoplasms.
    Yao J; Bergsland E; Aggarwal R; Aparicio A; Beltran H; Crabtree JS; Hann CL; Ibrahim T; Byers LA; Sasano H; Umejiego J; Pavel M
    Oncologist; 2022 Nov; 27(11):940-951. PubMed ID: 35983951
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.
    Sullivan PM; Kumar R; Li W; Hoglund V; Wang L; Zhang Y; Shi M; Beak D; Cheuk A; Jensen MC; Khan J; Dimitrov DS; Orentas RJ
    Mol Cancer Ther; 2022 Oct; 21(10):1608-1621. PubMed ID: 35877472
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Membrane-Anchored and Tumor-Targeted IL12 (attIL12)-PBMC Therapy for Osteosarcoma.
    Yang Q; Hu J; Jia Z; Wang Q; Wang J; Dao LH; Zhang W; Zhang S; Xia X; Gorlick R; Li S
    Clin Cancer Res; 2022 Sep; 28(17):3862-3873. PubMed ID: 35727602
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 4.