Terms: = Sarcomas AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602 AND Treatment
17 results:
1. Haploinsufficiency of the lysosomal sialidase NEU1 results in a model of pleomorphic rhabdomyosarcoma in mice.
Machado ER; van de Vlekkert D; Sheppard HS; Perry S; Downing SM; Laxton J; Ashmun R; Finkelstein DB; Neale GA; Hu H; Harwood FC; Koo SC; Grosveld GC; d'Azzo A
Commun Biol; 2022 Sep; 5(1):992. PubMed ID: 36127469
[TBL] [Abstract] [Full Text] [Related]
2. Metastatic Basal Cell Carcinoma Arising From a Primary Cutaneous Carcinosarcoma.
Sterner J; Rizk K; Braudis K; Tuncer T; Smith E
Oncology (Williston Park); 2021 Dec; 35(12):812-815. PubMed ID: 35088998
[TBL] [Abstract] [Full Text] [Related]
3. Integrative clinical and biopathology analyses to understand the clinical heterogeneity of infantile rhabdomyosarcoma: A report from the French MMT committee.
Butel T; Karanian M; Pierron G; Orbach D; Ranchere D; Cozic N; Galmiche L; Coulomb A; Corradini N; Lacour B; Proust S; Guerin F; Boutroux H; Rome A; Mansuy L; Vérité C; Defachelles AS; Tirode F; Minard-Colin V
Cancer Med; 2020 Apr; 9(8):2698-2709. PubMed ID: 32087612
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4. Wilms Tumor Associated With the 9q22.3 Microdeletion Syndrome: 2 New Case Reports and a Review of The Literature.
Cayrol J; Nightingale M; Challis J; Campbell M; Sullivan M; Heloury Y
J Pediatr Hematol Oncol; 2019 Nov; 41(8):e517-e520. PubMed ID: 30371535
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5. Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.
Campbell VT; Nadesan P; Ali SA; Wang CY; Whetstone H; Poon R; Wei Q; Keilty J; Proctor J; Wang LW; Apte SS; McGovern K; Alman BA; Wunder JS
Mol Cancer Ther; 2014 May; 13(5):1259-69. PubMed ID: 24634412
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6. Basal cell carcinosarcoma with ptch1 mutations in both epithelial and sarcomatoid primary tumor components and in the sarcomatoid metastasis.
Kiuru M; McDermott G; Coit DC; Berger MF; Busam KJ
Am J Surg Pathol; 2014 Jan; 38(1):138-42. PubMed ID: 24335643
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7. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
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8. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
[TBL] [Abstract] [Full Text] [Related]
9. Thyroid cancer cell resistance to gefitinib depends on the constitutive oncogenic activation of the ERK pathway.
Frasca F; Vella V; Nicolosi ML; Messina RL; Gianì F; Lotta S; Vigneri P; Regalbuto C; Vigneri R
J Clin Endocrinol Metab; 2013 Jun; 98(6):2502-12. PubMed ID: 23559083
[TBL] [Abstract] [Full Text] [Related]
10. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Kawabata N; Ijiri K; Ishidou Y; Yamamoto T; Nagao H; Nagano S; Maeda S; Komiya S; Setoguchi T
Int J Oncol; 2011 Oct; 39(4):899-906. PubMed ID: 21674124
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11. Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma.
Eichenmüller M; Hemmerlein B; von Schweinitz D; Kappler R
Br J Cancer; 2010 Jun; 103(1):43-51. PubMed ID: 20517313
[TBL] [Abstract] [Full Text] [Related]
12. (-)-Epigallocatechin-3-gallate induces apoptosis and suppresses proliferation by inhibiting the human Indian Hedgehog pathway in human chondrosarcoma cells.
Tang GQ; Yan TQ; Guo W; Ren TT; Peng CL; Zhao H; Lu XC; Zhao FL; Han X
J Cancer Res Clin Oncol; 2010 Aug; 136(8):1179-85. PubMed ID: 20127255
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13. Smoothened as a new therapeutic target for human osteosarcoma.
Hirotsu M; Setoguchi T; Sasaki H; Matsunoshita Y; Gao H; Nagao H; Kunigou O; Komiya S
Mol Cancer; 2010 Jan; 9():5. PubMed ID: 20067614
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14. Radiation-sensitive genetically susceptible pediatric sub-populations.
Kleinerman RA
Pediatr Radiol; 2009 Feb; 39 Suppl 1(Suppl 1):S27-31. PubMed ID: 19083227
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15. Cyclopamine treatment of full-blown Hh/ptch-associated RMS partially inhibits Hh/ptch signaling, but not tumor growth.
Ecke I; Rosenberger A; Obenauer S; Dullin C; Aberger F; Kimmina S; Schweyer S; Hahn H
Mol Carcinog; 2008 May; 47(5):361-72. PubMed ID: 17963245
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16. Sinonasal carcinoma after irradiation for medulloblastoma in nevoid basal cell carcinoma syndrome.
Wallin JL; Tanna N; Misra S; Puri PK; Sadeghi N
Am J Otolaryngol; 2007; 28(5):360-2. PubMed ID: 17826543
[TBL] [Abstract] [Full Text] [Related]
17. Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
Tiet TD; Hopyan S; Nadesan P; Gokgoz N; Poon R; Lin AC; Yan T; Andrulis IL; Alman BA; Wunder JS
Am J Pathol; 2006 Jan; 168(1):321-30. PubMed ID: 16400033
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