Terms: = Sarcomas AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx
26 results:
1. Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype.
Vaghjiani VG; Cochrane CR; Jayasekara WSN; Chong WC; Szczepny A; Kumar B; Martelotto LG; McCaw A; Carey K; Kansara M; Thomas DM; Walkley C; Mudge S; Gough DJ; Downie PA; Peacock CD; Matsui W; Watkins DN; Cain JE
Oncogene; 2023 Nov; 42(47):3529-3541. PubMed ID: 37845394
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2. Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model.
Garcia N; Ulin M; Ali M; Al-Hendy A; Carvalho KC; Yang Q
Reprod Sci; 2022 Mar; 29(3):781-790. PubMed ID: 34642915
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3. Differential gene expression analysis for osteosarcoma lung metastases.
Liu F; Pang X; Yu Z; Wang K
Cancer Biomark; 2022; 33(3):379-387. PubMed ID: 34511489
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4. Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade.
Wang W; Yan T; Guo W; Niu J; Zhao Z; Sun K; Zhang H; Yu Y; Ren T
Cell Death Differ; 2021 Jul; 28(7):2221-2237. PubMed ID: 33637972
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5. Hedgehog Signaling: Implications in Cancers and Viral Infections.
Iriana S; Asha K; Repak M; Sharma-Walia N
Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33494284
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6. Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells.
Garcia N; Al-Hendy A; Baracat EC; Carvalho KC; Yang Q
Cells; 2020 Dec; 10(1):. PubMed ID: 33396427
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7. The inhibition of microRNA-326 by SP1/HDAC1 contributes to proliferation and metastasis of osteosarcoma through promoting smo expression.
Huang JH; Xu Y; Lin FY
J Cell Mol Med; 2020 Sep; 24(18):10876-10888. PubMed ID: 32743904
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8. Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion.
Qu W; Li D; Wang Y; Wu Q; Hao D
Med Sci Monit; 2018 Jun; 24():3764-3771. PubMed ID: 29864766
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9. Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.
Taeubner J; Brozou T; Qin N; Bartl J; Ginzel S; Schaper J; Felsberg J; Fulda S; Vokuhl C; Borkhardt A; Kuhlen M
Eur J Hum Genet; 2018 Jan; 26(1):137-142. PubMed ID: 29230040
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10. Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.
Bernardini G; Geminiani M; Gambassi S; Orlandini M; Petricci E; Marzocchi B; Laschi M; Taddei M; Manetti F; Santucci A
J Cell Physiol; 2018 Jun; 233(6):4961-4971. PubMed ID: 29215700
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11. Primary Epithelioid Angiosarcoma of Finger Masquerading as Epithelioid Hemangioma: Report of a Case and Analysis of Mutational Pattern in Epithelioid Hemangiomas and Angiosarcomas by Next-generation Sequencing.
Subramaniam MM; Salleh NL; Wu B; Rozario MA; Lim H; Puhaindran ME; Soong R; Lee VK
Appl Immunohistochem Mol Morphol; 2018 Jan; 26(1):e7-e13. PubMed ID: 29206716
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12. May Sonic Hedgehog proteins be markers for malignancy in uterine smooth muscle tumors?
Garcia N; Bozzini N; Baiocchi G; da Cunha IW; Maciel GA; Soares Junior JM; Soares FA; Baracat EC; Carvalho KC
Hum Pathol; 2016 Apr; 50():43-50. PubMed ID: 26997437
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13. Regulatory network of differentially expressed genes in metastatic osteosarcoma.
Yao P; Wang ZB; Ding YY; Ma JM; Hong T; Pan SN; Zhang J
Mol Med Rep; 2015 Mar; 11(3):2104-10. PubMed ID: 25434727
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14. Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.
Campbell VT; Nadesan P; Ali SA; Wang CY; Whetstone H; Poon R; Wei Q; Keilty J; Proctor J; Wang LW; Apte SS; McGovern K; Alman BA; Wunder JS
Mol Cancer Ther; 2014 May; 13(5):1259-69. PubMed ID: 24634412
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15. The novel myxofibrosarcoma cell line MUG-Myx1 expresses a tumourigenic stem-like cell population with high aldehyde dehydrogenase 1 activity.
Lohberger B; Stuendl N; Wolf E; Liegl-Atzwanger B; Leithner A; Rinner B
BMC Cancer; 2013 Dec; 13():563. PubMed ID: 24289252
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16. Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.
Rajurkar M; Huang H; Cotton JL; Brooks JK; Sicklick J; McMahon AP; Mao J
Oncogene; 2014 Nov; 33(46):5370-8. PubMed ID: 24276242
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17. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
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18. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
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19. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Kawabata N; Ijiri K; Ishidou Y; Yamamoto T; Nagao H; Nagano S; Maeda S; Komiya S; Setoguchi T
Int J Oncol; 2011 Oct; 39(4):899-906. PubMed ID: 21674124
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20. Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group.
Pressey JG; Anderson JR; Crossman DK; Lynch JC; Barr FG
Pediatr Blood Cancer; 2011 Dec; 57(6):930-8. PubMed ID: 21618411
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