Terms: = Sarcomas AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx AND Treatment
12 results:
1. Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model.
Garcia N; Ulin M; Ali M; Al-Hendy A; Carvalho KC; Yang Q
Reprod Sci; 2022 Mar; 29(3):781-790. PubMed ID: 34642915
[TBL] [Abstract] [Full Text] [Related]
2. Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells.
Garcia N; Al-Hendy A; Baracat EC; Carvalho KC; Yang Q
Cells; 2020 Dec; 10(1):. PubMed ID: 33396427
[TBL] [Abstract] [Full Text] [Related]
3. The inhibition of microRNA-326 by SP1/HDAC1 contributes to proliferation and metastasis of osteosarcoma through promoting smo expression.
Huang JH; Xu Y; Lin FY
J Cell Mol Med; 2020 Sep; 24(18):10876-10888. PubMed ID: 32743904
[TBL] [Abstract] [Full Text] [Related]
4. Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.
Bernardini G; Geminiani M; Gambassi S; Orlandini M; Petricci E; Marzocchi B; Laschi M; Taddei M; Manetti F; Santucci A
J Cell Physiol; 2018 Jun; 233(6):4961-4971. PubMed ID: 29215700
[TBL] [Abstract] [Full Text] [Related]
5. Regulatory network of differentially expressed genes in metastatic osteosarcoma.
Yao P; Wang ZB; Ding YY; Ma JM; Hong T; Pan SN; Zhang J
Mol Med Rep; 2015 Mar; 11(3):2104-10. PubMed ID: 25434727
[TBL] [Abstract] [Full Text] [Related]
6. Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.
Campbell VT; Nadesan P; Ali SA; Wang CY; Whetstone H; Poon R; Wei Q; Keilty J; Proctor J; Wang LW; Apte SS; McGovern K; Alman BA; Wunder JS
Mol Cancer Ther; 2014 May; 13(5):1259-69. PubMed ID: 24634412
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7. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
[TBL] [Abstract] [Full Text] [Related]
8. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
[TBL] [Abstract] [Full Text] [Related]
9. Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Kawabata N; Ijiri K; Ishidou Y; Yamamoto T; Nagao H; Nagano S; Maeda S; Komiya S; Setoguchi T
Int J Oncol; 2011 Oct; 39(4):899-906. PubMed ID: 21674124
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10. smoothened as a new therapeutic target for human osteosarcoma.
Hirotsu M; Setoguchi T; Sasaki H; Matsunoshita Y; Gao H; Nagao H; Kunigou O; Komiya S
Mol Cancer; 2010 Jan; 9():5. PubMed ID: 20067614
[TBL] [Abstract] [Full Text] [Related]
11. Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth.
Ecke I; Rosenberger A; Obenauer S; Dullin C; Aberger F; Kimmina S; Schweyer S; Hahn H
Mol Carcinog; 2008 May; 47(5):361-72. PubMed ID: 17963245
[TBL] [Abstract] [Full Text] [Related]
12. Neoadjuvant chemotherapy for patients with synchronous multifocal osteosarcoma: results in eleven cases.
Longhi A; Fabbri N; Donati D; Capanna R; Briccoli A; Biagini R; Bernini G; Ferrari S; Versari M; Bacci G
J Chemother; 2001 Jun; 13(3):324-30. PubMed ID: 11450892
[TBL] [Abstract] [Full Text] [Related]