Terms: = Sarcomas AND TSC1, KIAA0243, 7248, ENSG00000165699, TSC, MGC86987, LAM, hamartin AND Treatment
24 results:
1. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
[TBL] [Abstract] [Full Text] [Related]
2. A Phase I/II Investigation of Safety and Efficacy of Nivolumab and
Gordon EM; Angel NL; Omelchenko N; Chua-Alcala VS; Moradkhani A; Quon D; Wong S
Anticancer Res; 2023 May; 43(5):1993-2002. PubMed ID: 37097693
[TBL] [Abstract] [Full Text] [Related]
3. A rare metastatic mesenteric malignant PEComa with tsc2 mutation treated with palliative surgical resection and nab-sirolimus: a case report.
Meredith L; Chao T; Nevler A; Basu Mallick A; Singla RK; McCue PA; Bowne WB; Jiang W
Diagn Pathol; 2023 Apr; 18(1):45. PubMed ID: 37041531
[TBL] [Abstract] [Full Text] [Related]
4. Uterine Leiomyosarcoma Masquerading as a Malignant Perivascular Epithelioid Cell Tumor: A Diagnostic Challenge.
Natsume T; Yoshida H; Nishikawa T; Kikkawa N; Naka T; Kobayashi-Kato M; Tanase Y; Uno M; Ishikawa M; Kato T
Int J Surg Pathol; 2023 Aug; 31(5):778-784. PubMed ID: 36310451
[TBL] [Abstract] [Full Text] [Related]
5. Phase II Study of TQB2450, a Novel PD-L1 Antibody, in Combination with Anlotinib in Patients with Locally Advanced or Metastatic Soft Tissue Sarcoma.
Liu J; Gao T; Tan Z; Li S; Xu J; Bai C; Xue R; Xie L; Zhang L; Fan Z; Guo W
Clin Cancer Res; 2022 Aug; 28(16):3473-3479. PubMed ID: 35675031
[TBL] [Abstract] [Full Text] [Related]
6. The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma.
Kang CW; Hannan KM; Blackburn AC; Loh AHP; Hong KC; Yuan GJ; Hein N; Drygin D; Hannan RD; Coupland LA
Invest New Drugs; 2022 Jun; 40(3):529-536. PubMed ID: 35201535
[TBL] [Abstract] [Full Text] [Related]
7. Translational Modeling of Anticancer Efficacy to Predict Clinical Outcomes in a First-in-Human Phase 1 Study of MDM2 Inhibitor HDM201.
Guerreiro N; Jullion A; Ferretti S; Fabre C; Meille C
AAPS J; 2021 Feb; 23(2):28. PubMed ID: 33554304
[TBL] [Abstract] [Full Text] [Related]
8. Incidence, treatment and outcome of abdominal metastases in extremity soft tissue sarcoma: Results from a multi-centre study.
Smolle MA; Schaffler A; Leithner A; Van Praag VM; Bergovec M; Szkandera J; Liegl-Atzwanger B; Niethard M; Tunn PU; Van De Sande M; Andreou D
J Surg Oncol; 2020 Mar; 121(4):605-611. PubMed ID: 32003475
[TBL] [Abstract] [Full Text] [Related]
9. KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy.
Mühlenberg T; Ketzer J; Heinrich MC; Grunewald S; Marino-Enriquez A; Trautmann M; Hartmann W; Wardelmann E; Treckmann J; Worm K; Bertram S; Herold T; Schildhaus HU; Glimm H; Stenzinger A; Brors B; Horak P; Hohenberger P; Fröhling S; Fletcher JA; Bauer S
Mol Cancer Ther; 2019 Nov; 18(11):1985-1996. PubMed ID: 31308077
[TBL] [Abstract] [Full Text] [Related]
10. Proliferative Cells From Kaposiform Lymphangiomatosis Lesions Resemble Mesenchyme Stem Cell-like Pericytes Defective in Vessel Formation.
Glaser K; Dickie P; Dickie BH
J Pediatr Hematol Oncol; 2018 Nov; 40(8):e495-e504. PubMed ID: 30256265
[TBL] [Abstract] [Full Text] [Related]
11. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.
Zhou H; Shang C; Wang M; Shen T; Kong L; Yu C; Ye Z; Luo Y; Liu L; Li Y; Huang S
Biochem Pharmacol; 2016 Sep; 116():39-50. PubMed ID: 27396756
[TBL] [Abstract] [Full Text] [Related]
12. Role of Prolactin Receptors in Lymphangioleiomyomatosis.
Alkharusi A; Lesma E; Ancona S; Chiaramonte E; Nyström T; Gorio A; Norstedt G
PLoS One; 2016; 11(1):e0146653. PubMed ID: 26765535
[TBL] [Abstract] [Full Text] [Related]
13. Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor.
Moavero R; Folgiero V; Carai A; Miele E; Ferretti E; Po A; Diomedi Camassei F; Lepri FR; Vigevano F; Curatolo P; Valeriani M; Colafati GS; Locatelli F; Tornesello A; Mastronuzzi A
Pediatr Blood Cancer; 2016 Apr; 63(4):719-22. PubMed ID: 26626406
[TBL] [Abstract] [Full Text] [Related]
14. Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya.
Ochwang'i DO; Kimwele CN; Oduma JA; Gathumbi PK; Mbaria JM; Kiama SG
J Ethnopharmacol; 2014 Feb; 151(3):1040-1055. PubMed ID: 24362078
[TBL] [Abstract] [Full Text] [Related]
15. Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Frau M; Feo F; Pascale RM
J Hepatol; 2013 Oct; 59(4):830-41. PubMed ID: 23665184
[TBL] [Abstract] [Full Text] [Related]
16. Extrarenal perivascular epithelioid cell tumors (PEComas) respond to mTOR inhibition: clinical and molecular correlates.
Dickson MA; Schwartz GK; Antonescu CR; Kwiatkowski DJ; Malinowska IA
Int J Cancer; 2013 Apr; 132(7):1711-7. PubMed ID: 22927055
[TBL] [Abstract] [Full Text] [Related]
17. Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
Saini V; Hose CD; Monks A; Nagashima K; Han B; Newton DL; Millione A; Shah J; Hollingshead MG; Hite KM; Burkett MW; Delosh RM; Silvers TE; Scudiero DA; Shoemaker RH
PLoS One; 2012; 7(8):e41401. PubMed ID: 22870217
[TBL] [Abstract] [Full Text] [Related]
18. Amplification of the angiogenic signal through the activation of the tsc/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.
Jham BC; Ma T; Hu J; Chaisuparat R; Friedman ER; Pandolfi PP; Schneider A; Sodhi A; Montaner S
PLoS One; 2011 Apr; 6(4):e19103. PubMed ID: 21559457
[TBL] [Abstract] [Full Text] [Related]
19. [Targeted treatment of rare connective tissue tumors and sarcomas].
Cassier P; Pissaloux D; Alberti L; Ray-Coquard I; Blay JY
Bull Cancer; 2010 Jun; 97(6):693-700. PubMed ID: 20497911
[TBL] [Abstract] [Full Text] [Related]
20. Sirolimus-induced signaling modifications in Kaposi's sarcoma with resolution in a liver transplant recipient.
Ho CM; Huang SF; Hu RH; Ho MC; Wu YM; Lee PH
Clin Transplant; 2010; 24(1):127-32. PubMed ID: 19919613
[TBL] [Abstract] [Full Text] [Related]
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