Terms: = Sarcomas AND TSC2, FLJ43106, 7249, ENSG00000103197, LAM, tuberin, TSC4 AND Treatment
20 results:
1. A Case Study of a Rare Undifferentiated Spindle Cell Sarcoma of the Penis: Establishment and Characterization of Patient-Derived Models.
Sousa ACDS; Fernandes BLNC; da Silva JPA; Stevanato Filho PR; Coimbra LBCT; de Oliveira Beserra A; Alvarenga AL; Maida G; Guimaraes CT; Nakamuta IM; Marchi FA; Alves C; Lichtenfels M; de Farias CB; Kupper BEC; Costa FD; de Mello CAL; Carraro DM; Torrezan GT; Lopes A; Dos Santos TG
Genes (Basel); 2024 Mar; 15(4):. PubMed ID: 38674359
[TBL] [Abstract] [Full Text] [Related]
2. A Phase I/II Investigation of Safety and Efficacy of Nivolumab and
Gordon EM; Angel NL; Omelchenko N; Chua-Alcala VS; Moradkhani A; Quon D; Wong S
Anticancer Res; 2023 May; 43(5):1993-2002. PubMed ID: 37097693
[TBL] [Abstract] [Full Text] [Related]
3. A rare metastatic mesenteric malignant PEComa with tsc2 mutation treated with palliative surgical resection and nab-sirolimus: a case report.
Meredith L; Chao T; Nevler A; Basu Mallick A; Singla RK; McCue PA; Bowne WB; Jiang W
Diagn Pathol; 2023 Apr; 18(1):45. PubMed ID: 37041531
[TBL] [Abstract] [Full Text] [Related]
4. LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and tsc2 ubiquitination.
Tsang SV; Rainusso N; Liu M; Nomura M; Patel TD; Nakahata K; Kim HR; Huang S; Rajapakshe K; Coarfa C; Man TK; Rao PH; Yustein JT
Oncogene; 2022 Dec; 41(50):5373-5384. PubMed ID: 36348010
[TBL] [Abstract] [Full Text] [Related]
5. Phase II Study of TQB2450, a Novel PD-L1 Antibody, in Combination with Anlotinib in Patients with Locally Advanced or Metastatic Soft Tissue Sarcoma.
Liu J; Gao T; Tan Z; Li S; Xu J; Bai C; Xue R; Xie L; Zhang L; Fan Z; Guo W
Clin Cancer Res; 2022 Aug; 28(16):3473-3479. PubMed ID: 35675031
[TBL] [Abstract] [Full Text] [Related]
6.
Wagner AJ; Ravi V; Riedel RF; Ganjoo K; Van Tine BA; Chugh R; Cranmer L; Gordon EM; Hornick JL; Du H; Grigorian B; Schmid AN; Hou S; Harris K; Kwiatkowski DJ; Desai NP; Dickson MA
J Clin Oncol; 2021 Nov; 39(33):3660-3670. PubMed ID: 34637337
[TBL] [Abstract] [Full Text] [Related]
7. tsc2-mutant uterine sarcomas with JAZF1-SUZ12 fusions demonstrate hybrid features of endometrial stromal sarcoma and PEComa and are responsive to mTOR inhibition.
Chiang S; Vasudevaraja V; Serrano J; Stewart CJR; Oliva E; Momeni-Boroujeni A; Jungbluth AA; Da Cruz Paula A; da Silva EM; Weigelt B; Park KJ; Soslow RA; Murali R; Ellenson LH; Benayed R; Ladanyi M; Abu-Rustum NR; Dickson MA; Cohen S; Aghajanian C; Hensley ML; Lee CH; Snuderl M; Konner JA
Mod Pathol; 2022 Jan; 35(1):117-127. PubMed ID: 34561551
[TBL] [Abstract] [Full Text] [Related]
8. Incidence, treatment and outcome of abdominal metastases in extremity soft tissue sarcoma: Results from a multi-centre study.
Smolle MA; Schaffler A; Leithner A; Van Praag VM; Bergovec M; Szkandera J; Liegl-Atzwanger B; Niethard M; Tunn PU; Van De Sande M; Andreou D
J Surg Oncol; 2020 Mar; 121(4):605-611. PubMed ID: 32003475
[TBL] [Abstract] [Full Text] [Related]
9. KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy.
Mühlenberg T; Ketzer J; Heinrich MC; Grunewald S; Marino-Enriquez A; Trautmann M; Hartmann W; Wardelmann E; Treckmann J; Worm K; Bertram S; Herold T; Schildhaus HU; Glimm H; Stenzinger A; Brors B; Horak P; Hohenberger P; Fröhling S; Fletcher JA; Bauer S
Mol Cancer Ther; 2019 Nov; 18(11):1985-1996. PubMed ID: 31308077
[TBL] [Abstract] [Full Text] [Related]
10. Profiles of genomic alterations in primary esophageal follicular dendritic cell sarcoma: A case report.
Ren W; Sun Q; Wu PY; Huang B; Yang J; Yan J; Liu BR
Medicine (Baltimore); 2018 Nov; 97(48):e13413. PubMed ID: 30508944
[TBL] [Abstract] [Full Text] [Related]
11. Targetable Alterations in Adult Patients With Soft-Tissue sarcomas: Insights for Personalized Therapy.
Lucchesi C; Khalifa E; Laizet Y; Soubeyran I; Mathoulin-Pelissier S; Chomienne C; Italiano A
JAMA Oncol; 2018 Oct; 4(10):1398-1404. PubMed ID: 29801054
[TBL] [Abstract] [Full Text] [Related]
12. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.
Zhou H; Shang C; Wang M; Shen T; Kong L; Yu C; Ye Z; Luo Y; Liu L; Li Y; Huang S
Biochem Pharmacol; 2016 Sep; 116():39-50. PubMed ID: 27396756
[TBL] [Abstract] [Full Text] [Related]
13. Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity.
Liu SY; Joseph NM; Ravindranathan A; Stohr BA; Greenland NY; Vohra P; Hosfield E; Yeh I; Talevich E; Onodera C; Van Ziffle JA; Grenert JP; Bastian BC; Chen YY; Krings G
Mod Pathol; 2016 Sep; 29(9):1012-27. PubMed ID: 27255162
[TBL] [Abstract] [Full Text] [Related]
14. Role of Prolactin Receptors in Lymphangioleiomyomatosis.
Alkharusi A; Lesma E; Ancona S; Chiaramonte E; Nyström T; Gorio A; Norstedt G
PLoS One; 2016; 11(1):e0146653. PubMed ID: 26765535
[TBL] [Abstract] [Full Text] [Related]
15. Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor.
Moavero R; Folgiero V; Carai A; Miele E; Ferretti E; Po A; Diomedi Camassei F; Lepri FR; Vigevano F; Curatolo P; Valeriani M; Colafati GS; Locatelli F; Tornesello A; Mastronuzzi A
Pediatr Blood Cancer; 2016 Apr; 63(4):719-22. PubMed ID: 26626406
[TBL] [Abstract] [Full Text] [Related]
16. Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya.
Ochwang'i DO; Kimwele CN; Oduma JA; Gathumbi PK; Mbaria JM; Kiama SG
J Ethnopharmacol; 2014 Feb; 151(3):1040-1055. PubMed ID: 24362078
[TBL] [Abstract] [Full Text] [Related]
17. Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Frau M; Feo F; Pascale RM
J Hepatol; 2013 Oct; 59(4):830-41. PubMed ID: 23665184
[TBL] [Abstract] [Full Text] [Related]
18. Extrarenal perivascular epithelioid cell tumors (PEComas) respond to mTOR inhibition: clinical and molecular correlates.
Dickson MA; Schwartz GK; Antonescu CR; Kwiatkowski DJ; Malinowska IA
Int J Cancer; 2013 Apr; 132(7):1711-7. PubMed ID: 22927055
[TBL] [Abstract] [Full Text] [Related]
19. Sirolimus-induced signaling modifications in Kaposi's sarcoma with resolution in a liver transplant recipient.
Ho CM; Huang SF; Hu RH; Ho MC; Wu YM; Lee PH
Clin Transplant; 2010; 24(1):127-32. PubMed ID: 19919613
[TBL] [Abstract] [Full Text] [Related]
20. Lymphangiomyomatosis of the uterus associated with tuberous sclerosis and malignant neoplasia of the female genital tract: a report of two cases.
Gyure KA; Hart WR; Kennedy AW
Int J Gynecol Pathol; 1995 Oct; 14(4):344-51. PubMed ID: 8598338
[TBL] [Abstract] [Full Text] [Related]
