BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND uPA
132 results:

  • 1. Morin inhibits osteosarcoma migration and invasion by suppressing urokinase plasminogen activator through a signal transducer and an activator of transcription 3.
    Yang JS; Chou CH; Hsieh YH; Lu PW; Lin YC; Yang SF; Lu KH
    Environ Toxicol; 2024 Apr; 39(4):2024-2031. PubMed ID: 38093596
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Ulipristal acetate, a selective progesterone receptor modulator, induces cell death via inhibition of STAT3/CCL2 signaling pathway in uterine sarcoma.
    Hwang JR; Cho YJ; Ryu JY; Choi JY; Choi JJ; Sa JK; Kim HS; Lee JW
    Biomed Pharmacother; 2023 Dec; 168():115792. PubMed ID: 37924789
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion via affecting the PI3K/Akt/NF‑κB, PI3K/Akt/GSK3β and MAPK signaling pathways
    Ma YS; Peng SF; Wu RS; Chueh FS; Huang WW; Chen PY; Kuo CL; Huang AC; Liao CL; Hsia TC
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36222295
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma.
    Matsuyama A; Wood GA; Speare R; Schott CR; Mutsaers AJ
    PLoS One; 2022; 17(9):e0273811. PubMed ID: 36174075
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cinnamaldehyde decreases the invasion and u-PA expression of osteosarcoma by down-regulating the FAK signalling pathway.
    Chu SC; Hsieh YS; Hsu LS; Lin CY; Lai YA; Chen PN
    Food Funct; 2022 Jun; 13(12):6574-6582. PubMed ID: 35678522
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. KSHV-encoded ORF45 activates human NLRP1 inflammasome.
    Yang X; Zhou J; Liu C; Qu Y; Wang W; Xiao MZX; Zhu F; Liu Z; Liang Q
    Nat Immunol; 2022 Jun; 23(6):916-926. PubMed ID: 35618833
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Dihydromyricetin suppresses cell metastasis in human osteosarcoma through SP-1- and NF-κB-modulated urokinase plasminogen activator inhibition.
    Chou CH; Lu KH; Yang JS; Hsieh YH; Lin CW; Yang SF
    Phytomedicine; 2021 Sep; 90():153642. PubMed ID: 34265701
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells' Migration and Invasion in Culture by Inhibition of upa via the JAK/STAT Signaling Pathway.
    Lu KH; Wu HH; Lin RC; Lin YC; Lu PW; Yang SF; Yang JS
    Molecules; 2020 Dec; 26(1):. PubMed ID: 33374783
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Inhibitory Effects of a Reengineered Anthrax Toxin on Canine and Human Osteosarcoma Cells.
    Mackowiak da Fonseca J; Mackowiak da Fonseca II; Nagamine MK; Massoco CO; Nishiya AT; Ward JM; Liu S; Leppla SH; Bugge TH; Dagli MLZ
    Toxins (Basel); 2020 Sep; 12(10):. PubMed ID: 32987941
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Fisetin Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion
    Chen JK; Peng SF; Lai KC; Liu HC; Huang YP; Lin CC; Huang AC; Chueh FS; Chung JG
    In Vivo; 2019; 33(3):801-810. PubMed ID: 31028200
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Lupeol suppresses migration and invasion
    Hsu MJ; Peng SF; Chueh FS; Tsai CH; Tsai FJ; Huang CY; Tang CH; Yang JS; Hsu YM; Huang WW; Chung JG
    Biosci Biotechnol Biochem; 2019 Sep; 83(9):1729-1739. PubMed ID: 31010399
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Failure of ulipristal acetate treatment as an indication for uterine malignancy: Two case reports.
    Santoro A; Angelico G; Arciuolo D; Inzani F; Fanfani F; Romualdi D; Scambia G; Zannoni GF
    Medicine (Baltimore); 2018 Aug; 97(31):e11532. PubMed ID: 30075519
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.
    Greither T; Wedler A; Rot S; Keßler J; Kehlen A; Holzhausen HJ; Bache M; Würl P; Taubert H; Kappler M
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29215551
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Unexpected uterine leiomyosarcoma in a woman with multiple myomas treated with ulipristal acetate: case report and literature review.
    Modaffari P; D'alonzo M; Garbagnati M; Pecchio S; Menato G; Biglia N
    Gynecol Endocrinol; 2018 Mar; 34(3):192-194. PubMed ID: 28933575
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. 3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo.
    Lu KH; Chen PN; Hsieh YH; Lin CY; Cheng FY; Chiu PC; Chu SC; Hsieh YS
    Food Chem Toxicol; 2016 Nov; 97():177-186. PubMed ID: 27600294
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Unexpected Uterine Leiomyosarcoma During Laparoscopic Hysterectomy Treated 6 Months With Ulipristal Acetate and Contained Power Morcellation.
    Istre O
    J Minim Invasive Gynecol; 2017 Feb; 24(2):198. PubMed ID: 27539216
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. c-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines.
    Gravina GL; Festuccia C; Popov VM; Di Rocco A; Colapietro A; Sanità P; Monache SD; Musio D; De Felice F; Di Cesare E; Tombolini V; Marampon F
    Radiat Res; 2016 Apr; 185(4):411-22. PubMed ID: 27104757
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine upa Axis.
    Endo-Munoz L; Cai N; Cumming A; Macklin R; Merida de Long L; Topkas E; Mukhopadhyay P; Hill M; Saunders NA
    PLoS One; 2015; 10(8):e0133592. PubMed ID: 26317203
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro.
    Shang HS; Chang JB; Lin JH; Lin JP; Hsu SC; Liu CM; Liu JY; Wu PP; Lu HF; Au MK; Chung JG
    Molecules; 2014 Oct; 19(10):16588-608. PubMed ID: 25322282
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells.
    Kim SR; Eom TK; Byun HG
    J Pept Sci; 2014 Sep; 20(9):716-24. PubMed ID: 24956509
    [TBL] [Abstract] [Full Text] [Related]  


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