BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND uPA AND Treatment
36 results:

  • 1. Morin inhibits osteosarcoma migration and invasion by suppressing urokinase plasminogen activator through a signal transducer and an activator of transcription 3.
    Yang JS; Chou CH; Hsieh YH; Lu PW; Lin YC; Yang SF; Lu KH
    Environ Toxicol; 2024 Apr; 39(4):2024-2031. PubMed ID: 38093596
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Ulipristal acetate, a selective progesterone receptor modulator, induces cell death via inhibition of STAT3/CCL2 signaling pathway in uterine sarcoma.
    Hwang JR; Cho YJ; Ryu JY; Choi JY; Choi JJ; Sa JK; Kim HS; Lee JW
    Biomed Pharmacother; 2023 Dec; 168():115792. PubMed ID: 37924789
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Bisdemethoxycurcumin suppresses human osteosarcoma U‑2 OS cell migration and invasion via affecting the PI3K/Akt/NF‑κB, PI3K/Akt/GSK3β and MAPK signaling pathways
    Ma YS; Peng SF; Wu RS; Chueh FS; Huang WW; Chen PY; Kuo CL; Huang AC; Liao CL; Hsia TC
    Oncol Rep; 2022 Dec; 48(6):. PubMed ID: 36222295
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Dihydromyricetin suppresses cell metastasis in human osteosarcoma through SP-1- and NF-κB-modulated urokinase plasminogen activator inhibition.
    Chou CH; Lu KH; Yang JS; Hsieh YH; Lin CW; Yang SF
    Phytomedicine; 2021 Sep; 90():153642. PubMed ID: 34265701
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells' Migration and Invasion in Culture by Inhibition of upa via the JAK/STAT Signaling Pathway.
    Lu KH; Wu HH; Lin RC; Lin YC; Lu PW; Yang SF; Yang JS
    Molecules; 2020 Dec; 26(1):. PubMed ID: 33374783
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Inhibitory Effects of a Reengineered Anthrax Toxin on Canine and Human Osteosarcoma Cells.
    Mackowiak da Fonseca J; Mackowiak da Fonseca II; Nagamine MK; Massoco CO; Nishiya AT; Ward JM; Liu S; Leppla SH; Bugge TH; Dagli MLZ
    Toxins (Basel); 2020 Sep; 12(10):. PubMed ID: 32987941
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Fisetin Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion
    Chen JK; Peng SF; Lai KC; Liu HC; Huang YP; Lin CC; Huang AC; Chueh FS; Chung JG
    In Vivo; 2019; 33(3):801-810. PubMed ID: 31028200
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Failure of ulipristal acetate treatment as an indication for uterine malignancy: Two case reports.
    Santoro A; Angelico G; Arciuolo D; Inzani F; Fanfani F; Romualdi D; Scambia G; Zannoni GF
    Medicine (Baltimore); 2018 Aug; 97(31):e11532. PubMed ID: 30075519
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Unexpected uterine leiomyosarcoma in a woman with multiple myomas treated with ulipristal acetate: case report and literature review.
    Modaffari P; D'alonzo M; Garbagnati M; Pecchio S; Menato G; Biglia N
    Gynecol Endocrinol; 2018 Mar; 34(3):192-194. PubMed ID: 28933575
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Unexpected Uterine Leiomyosarcoma During Laparoscopic Hysterectomy Treated 6 Months With Ulipristal Acetate and Contained Power Morcellation.
    Istre O
    J Minim Invasive Gynecol; 2017 Feb; 24(2):198. PubMed ID: 27539216
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. c-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines.
    Gravina GL; Festuccia C; Popov VM; Di Rocco A; Colapietro A; Sanità P; Monache SD; Musio D; De Felice F; Di Cesare E; Tombolini V; Marampon F
    Radiat Res; 2016 Apr; 185(4):411-22. PubMed ID: 27104757
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro.
    Shang HS; Chang JB; Lin JH; Lin JP; Hsu SC; Liu CM; Liu JY; Wu PP; Lu HF; Au MK; Chung JG
    Molecules; 2014 Oct; 19(10):16588-608. PubMed ID: 25322282
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Seahorse-derived peptide suppresses invasive migration of HT1080 fibrosarcoma cells by competing with intracellular α-enolase for plasminogen binding and inhibiting upa-mediated activation of plasminogen.
    Kim YT; Kim SK; Jeon YJ; Park SJ
    BMB Rep; 2014 Dec; 47(12):691-6. PubMed ID: 24602611
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines.
    Roomi MW; Kalinovsky T; Niedzwiecki A; Rath M
    Int J Oncol; 2013 Oct; 43(4):1027-35. PubMed ID: 23900236
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells.
    Chen HJ; Lin CM; Lee CY; Shih NC; Peng SF; Tsuzuki M; Amagaya S; Huang WW; Yang JS
    Oncol Rep; 2013 Aug; 30(2):925-32. PubMed ID: 23708932
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
    Roomi MW; Kalinovsky T; Niedzwiecki A; Rath M
    Int J Oncol; 2013 Jul; 43(1):39-49. PubMed ID: 23661254
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. upaR mediates anticancer activity of PEDF.
    Dass CR; Choong PF
    Cancer Biol Ther; 2008 Aug; 7(8):1262-70. PubMed ID: 18487955
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins.
    Vial D; McKeown-Longo PJ
    J Cell Sci; 2008 May; 121(Pt 10):1661-70. PubMed ID: 18445685
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation.
    Madsen MA; Deryugina EI; Niessen S; Cravatt BF; Quigley JP
    J Biol Chem; 2006 Jun; 281(23):15997-6005. PubMed ID: 16611636
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Arsenic trioxide (As2O3) inhibits invasion of HT1080 human fibrosarcoma cells: role of nuclear factor-kappaB and reactive oxygen species.
    Park MJ; Lee JY; Kwak HJ; Park CM; Lee HC; Woo SH; Jin HO; Han CJ; An S; Lee SH; Chung HY; Park IC; Hong SI; Rhee CH
    J Cell Biochem; 2005 Aug; 95(5):955-69. PubMed ID: 15962302
    [TBL] [Abstract] [Full Text] [Related]  


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