BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND HER1, YOR227W
34 results:

  • 1. First-in-human trial exploring safety, antitumor activity, and pharmacokinetics of Sym013, a recombinant pan-HER antibody mixture, in advanced epithelial malignancies.
    Berlin J; Tolcher AW; Ding C; Whisenant JG; Horak ID; Wood DL; Nadler PI; Hansen UH; Lantto J; Skartved NJØ; Pedersen MW; Patnaik A
    Invest New Drugs; 2022 Jun; 40(3):586-595. PubMed ID: 35113285
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The Yin and Yang of ERBB4: Tumor Suppressor and Oncoprotein.
    Lucas LM; Dwivedi V; Senfeld JI; Cullum RL; Mill CP; Piazza JT; Bryant IN; Cook LJ; Miller ST; Lott JH; Kelley CM; Knerr EL; Markham JA; Kaufmann DP; Jacobi MA; Shen J; Riese DJ
    Pharmacol Rev; 2022 Jan; 74(1):18-47. PubMed ID: 34987087
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Radiolabeled F(ab')
    Bellaye PS; Moreau M; Raguin O; Oudot A; Bernhard C; Vrigneaud JM; Dumont L; Vandroux D; Denat F; Cochet A; Brunotte F; Collin B
    Clin Transl Oncol; 2018 Dec; 20(12):1557-1570. PubMed ID: 29777377
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.
    Beretta GL; De Cesare M; Albano L; Magnifico A; Carenini N; Corna E; Perego P; Gatti L
    Tumori; 2016; 102(2):144-9. PubMed ID: 26917410
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A phase 1 study of intermittently administered pazopanib in combination with continuous daily dosing of lapatinib in patients with solid tumors.
    Henary H; George GC; Wheler J; Naing A; Piha-Paul S; Fu S; Mistry R; Zinner R; Kurzrock R; Hong DS
    Cancer Chemother Pharmacol; 2015 Sep; 76(3):597-603. PubMed ID: 26210681
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Dual targeting of her1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the "THERAPY"phase 1-2 trial.
    Assenat E; Azria D; Mollevi C; Guimbaud R; Tubiana-Mathieu N; Smith D; Delord JP; Samalin E; Portales F; Larbouret C; Robert B; Bibeau F; Bleuse JP; Crapez E; Ychou M; Pèlegrin A
    Oncotarget; 2015 May; 6(14):12796-808. PubMed ID: 25918250
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Preclinical pharmacokinetics, pharmacodynamics, and efficacy of RG7116: a novel humanized, glycoengineered anti-HER3 antibody.
    Meneses-Lorente G; Friess T; Kolm I; Hölzlwimmer G; Bader S; Meille C; Thomas M; Bossenmaier B
    Cancer Chemother Pharmacol; 2015 Apr; 75(4):837-50. PubMed ID: 25702049
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Ectodomain-specific E-cadherin antibody suppresses skin SCC growth and reduces tumor grade: a multitargeted therapy modulating RTKs and the PTEN-p53-MDM2 axis.
    Brouxhon SM; Kyrkanides S; Raja V; Silberfeld A; Teng X; Trochesset D; Cohen J; Ma L
    Mol Cancer Ther; 2014 Jul; 13(7):1791-802. PubMed ID: 24748654
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A phase 2 trial of dacomitinib (PF-00299804), an oral, irreversible pan-HER (human epidermal growth factor receptor) inhibitor, in patients with advanced non-small cell lung cancer after failure of prior chemotherapy and erlotinib.
    Reckamp KL; Giaccone G; Camidge DR; Gadgeel SM; Khuri FR; Engelman JA; Koczywas M; Rajan A; Campbell AK; Gernhardt D; Ruiz-Garcia A; Letrent S; Liang J; Taylor I; O'Connell JP; Jänne PA
    Cancer; 2014 Apr; 120(8):1145-54. PubMed ID: 24501009
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Non-clinical immuno-toxicological evaluation of her1 cancer vaccine in non-human primates: a 12-month study.
    Barro AM; Rivero AI; Goñi AL; Navarro BO; Angarica MM; Ramírez BS; Bedoya DM; Triana CG; Rodríguez AM; Parada ÁC
    Vaccine; 2012 Dec; 31(1):89-95. PubMed ID: 23142132
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Subacute transient encephalopathy induced by erlotinib.
    Okyuama T; Akazawa Y; Uchida J; Nishino K; Kumagai T; Imamura F
    Oncol Res; 2011; 19(8-9):399-402. PubMed ID: 22329199
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Phase I study of continuous afatinib (BIBW 2992) in patients with advanced non-small cell lung cancer after prior chemotherapy/erlotinib/gefitinib (LUX-Lung 4).
    Murakami H; Tamura T; Takahashi T; Nokihara H; Naito T; Nakamura Y; Nishio K; Seki Y; Sarashina A; Shahidi M; Yamamoto N
    Cancer Chemother Pharmacol; 2012 Apr; 69(4):891-9. PubMed ID: 22071596
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Objective response with lapatinib in patients with meningitis carcinomatosa derived from HER2/her1-negative breast cancer.
    Onishi H; Morisaki T; Nakafusa Y; Nakashima Y; Yokohata K; Katano M
    Int J Clin Oncol; 2011 Dec; 16(6):718-21. PubMed ID: 21327450
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Tufted hair folliculitis in a woman treated with trastuzumab.
    Rosman IS; Anadkat MJ
    Target Oncol; 2010 Dec; 5(4):295-6. PubMed ID: 20949375
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. [Current options and principles of pathomorphology-based tumour diagnostics].
    Povýsil C
    Vnitr Lek; 2010 Jul; 56(7):709-14. PubMed ID: 20842917
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Histopathologic and immunohistochemical characterization of rash to human epidermal growth factor receptor 1 (her1) and her1/2 inhibitors in cancer patients.
    Nardone B; Nicholson K; Newman M; Guitart J; Gerami P; Talarico N; Yang XJ; Rademaker A; West DP; Lacouture ME
    Clin Cancer Res; 2010 Sep; 16(17):4452-60. PubMed ID: 20732960
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. ErbB receptor tyrosine kinases contribute to proliferation of malignant melanoma cells: inhibition by gefitinib (ZD1839).
    Djerf EA; Trinks C; Abdiu A; Thunell LK; Hallbeck AL; Walz TM
    Melanoma Res; 2009 Jun; 19(3):156-66. PubMed ID: 19434003
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer.
    Dickler MN; Rugo HS; Eberle CA; Brogi E; Caravelli JF; Panageas KS; Boyd J; Yeh B; Lake DE; Dang CT; Gilewski TA; Bromberg JF; Seidman AD; D'Andrea GM; Moasser MM; Melisko M; Park JW; Dancey J; Norton L; Hudis CA
    Clin Cancer Res; 2008 Dec; 14(23):7878-83. PubMed ID: 19047117
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Epidermal growth factor receptor inhibitor-related skin toxicity: mechanisms, treatment, and its potential role as a predictive marker.
    Bianchini D; Jayanth A; Chua YJ; Cunningham D
    Clin Colorectal Cancer; 2008 Jan; 7(1):33-43. PubMed ID: 18279575
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting.
    Gridelli C; Maione P; Amoroso D; Baldari M; Bearz A; Bettoli V; Cammilluzzi E; Crinò L; De Marinis F; Di Pietro FA; Grossi F; Innocenzi D; Micali G; Piantedosi FV; Scartozzi M
    Crit Rev Oncol Hematol; 2008 May; 66(2):155-62. PubMed ID: 18083041
    [TBL] [Abstract] [Full Text] [Related]  


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