Terms: = Skin cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884
131 results:
1. Combined BRAF, MEK, and heat-shock protein 90 inhibition in advanced BRAF V600-mutant melanoma.
Eroglu Z; Chen YA; Smalley I; Li J; Markowitz JK; Brohl AS; Tetteh L; Taylor H; Sondak VK; Khushalani NI; Smalley KSM
Cancer; 2024 Jan; 130(2):232-243. PubMed ID: 37776537
[TBL] [Abstract] [Full Text] [Related]
2. Identification of circRNA-miRNA-mRNA Network Regulated by hsp90 in Human Melanoma A375 Cells.
Fu Q; Gao H; Liu K; Su J; Zhang J; Guo X; Yang F
Comb Chem High Throughput Screen; 2024; 27(2):307-316. PubMed ID: 37303182
[TBL] [Abstract] [Full Text] [Related]
3. In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity.
Ma S; Huis In't Veld RV; Houy A; Stern MH; Rich C; Ossendorp FA; Jager MJ
Invest Ophthalmol Vis Sci; 2023 Jun; 64(7):10. PubMed ID: 37272766
[TBL] [Abstract] [Full Text] [Related]
4. Dose-escalation trial of combination dabrafenib, trametinib, and AT13387 in patients with BRAF-mutant solid tumors.
Mooradian MJ; Cleary JM; Giobbie-Hurder A; Darville LNF; Parikh A; Buchbinder EI; Cohen JV; Lawrence DP; Shapiro GI; Keer H; Chen HX; Ivy SP; Smalley KSM; Koomen JM; Sullivan RJ
Cancer; 2023 Jun; 129(12):1904-1918. PubMed ID: 37042037
[TBL] [Abstract] [Full Text] [Related]
5. FKBP51 plays an essential role in Akt ubiquitination that requires hsp90 and PHLPP.
Tufano M; Marrone L; D'Ambrosio C; Di Giacomo V; Urzini S; Xiao Y; Matuozzo M; Scaloni A; Romano MF; Romano S
Cell Death Dis; 2023 Feb; 14(2):116. PubMed ID: 36781840
[TBL] [Abstract] [Full Text] [Related]
6. The Distinct Assignments for hsp90α and hsp90β: More Than skin Deep.
Chang C; Tang X; Woodley DT; Chen M; Li W
Cells; 2023 Jan; 12(2):. PubMed ID: 36672211
[TBL] [Abstract] [Full Text] [Related]
7. Extracellular Heat Shock Protein-90 (ehsp90): Everything You Need to Know.
Jay D; Luo Y; Li W
Biomolecules; 2022 Jun; 12(7):. PubMed ID: 35883467
[TBL] [Abstract] [Full Text] [Related]
8. SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma Cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib.
Kretschmer N; Durchschein C; Hufner A; Rinner B; Lohberger B; Bauer R
Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628494
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9. hsp90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma.
Sasame J; Ikegaya N; Kawazu M; Natsumeda M; Hayashi T; Isoda M; Satomi K; Tomiyama A; Oshima A; Honma H; Miyake Y; Takabayashi K; Nakamura T; Ueno T; Matsushita Y; Iwashita H; Kanemaru Y; Murata H; Ryo A; Terashima K; Yamanaka S; Fujii Y; Mano H; Komori T; Ichimura K; Cahill DP; Wakimoto H; Yamamoto T; Tateishi K
Clin Cancer Res; 2022 Jun; 28(11):2425-2439. PubMed ID: 35344043
[TBL] [Abstract] [Full Text] [Related]
10. Mechanisms underlying melanoma invasion as a consequence of MLK3 loss.
Balinda HU; Sedgwick A; D'Souza-Schorey C
Exp Cell Res; 2022 Jun; 415(1):113106. PubMed ID: 35307409
[TBL] [Abstract] [Full Text] [Related]
11. hsp90/IKK-rich small extracellular vesicles activate pro-angiogenic melanoma-associated fibroblasts via the NF-κB/CXCL1 axis.
Tang H; Zhou X; Zhao X; Luo X; Luo T; Chen Y; Liang W; Jiang E; Liu K; Shao Z; Shang Z
Cancer Sci; 2022 Apr; 113(4):1168-1181. PubMed ID: 35043517
[TBL] [Abstract] [Full Text] [Related]
12. Quercetin increases mitochondrial proteins (VDAC and SDH) and downmodulates AXL and PIM-1 tyrosine kinase receptors in NRAS melanoma cells.
Rocha-Brito KJP; Clerici SP; Cordeiro HG; Scotá Ferreira AP; Barreto Fonseca EM; Gonçalves PR; Abrantes JLF; Milani R; Massaro RR; Maria-Engler SS; Ferreira-Halder CV
Biol Chem; 2022 Feb; 403(3):293-303. PubMed ID: 34854272
[TBL] [Abstract] [Full Text] [Related]
13. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) sensitize melanoma cells to MEK inhibition and inhibit metastasis and relapse by inducing degradation of AXL.
Chen Y; Zhang Y; Chen S; Liu W; Lin Y; Zhang H; Yu F
Pigment Cell Melanoma Res; 2022 Mar; 35(2):238-251. PubMed ID: 34748282
[TBL] [Abstract] [Full Text] [Related]
14. Circ_NCKAP1 promotes skin basal cell carcinoma progression by sponging the miR-148b-5p/hsp90 axis.
Fan ZX; Xi W; Miao XY; Li LY; Miao GY
Eur Rev Med Pharmacol Sci; 2021 Sep; 25(17):5355-5364. PubMed ID: 34533810
[TBL] [Abstract] [Full Text] [Related]
15. hsp90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts.
Pipalia NH; Saad SZ; Subramanian K; Cross A; Al-Motawa A; Garg K; Blagg BSJ; Neckers L; Helquist P; Wiest O; Ory DS; Maxfield FR
J Lipid Res; 2021; 62():100114. PubMed ID: 34481829
[TBL] [Abstract] [Full Text] [Related]
16. A novel C-terminal hsp90 inhibitor KU758 synergizes efficacy in combination with BRAF or MEK inhibitors and targets drug-resistant pathways in BRAF-mutant melanomas.
Sanchez JN; Subramanian C; Chanda M; Shanguan G; Zhang N; Wang T; Timmermann BN; Blagg BSJ; Cohen MS
Melanoma Res; 2021 Jun; 31(3):197-207. PubMed ID: 33904516
[TBL] [Abstract] [Full Text] [Related]
17. Glucocorticoid receptor-targeted liposomal delivery system for delivering small molecule ESC8 and anti-miR-hsp90 gene construct to combat colon cancer.
Jinka S; Rachamalla HK; Bhattacharyya T; Sridharan K; Sekhar Jaggarapu MMC; Yakati V; Banerjee R
Biomed Mater; 2021 Feb; 16(2):024105. PubMed ID: 33434900
[TBL] [Abstract] [Full Text] [Related]
18. Tyrosinase-mediated melanogenesis in melanoma cells: Array comparative genome hybridization integrating proteomics and bioinformatics studies.
Yin SJ; Lee JR; Hahn MJ; Yang JM; Qian GY; Park YD
Int J Biol Macromol; 2021 Feb; 170():150-163. PubMed ID: 33359255
[TBL] [Abstract] [Full Text] [Related]
19. Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines.
Close DA; Kirkwood JM; Fecek RJ; Storkus WJ; Johnston PA
SLAS Discov; 2021 Jun; 26(5):712-729. PubMed ID: 33208016
[TBL] [Abstract] [Full Text] [Related]
20. Sulfoxythiocarbamate S-4 inhibits hsp90 in human cutaneous squamous cell carcinoma cells.
Zhang Y; VanHecke GC; Ahn YH; Proby CM; Dinkova-Kostova AT
Eur J Pharmacol; 2020 Dec; 889():173609. PubMed ID: 33031796
[TBL] [Abstract] [Full Text] [Related]
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