BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
44 results:

  • 1. Sunset Yellow protects against oxidative damage and exhibits chemoprevention in chemically induced skin cancer model.
    Singh S; Yadav S; Cavallo C; Mourya D; Singh I; Kumar V; Shukla S; Shukla P; Chaudhary R; Maurya GP; Müller RLJ; Rohde L; Mishra A; Wolkenhauer O; Gupta S; Tripathi A
    NPJ Syst Biol Appl; 2024 Mar; 10(1):23. PubMed ID: 38431714
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. keap1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance.
    Zavitsanou AM; Pillai R; Hao Y; Wu WL; Bartnicki E; Karakousi T; Rajalingam S; Herrera A; Karatza A; Rashidfarrokhi A; Solis S; Ciampricotti M; Yeaton AH; Ivanova E; Wohlhieter CA; Buus TB; Hayashi M; Karadal-Ferrena B; Pass HI; Poirier JT; Rudin CM; Wong KK; Moreira AL; Khanna KM; Tsirigos A; Papagiannakopoulos T; Koralov SB
    Cell Rep; 2023 Nov; 42(11):113295. PubMed ID: 37889752
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Nrf2 protein in melanoma progression, as a new means of treatment.
    Feng Q; Xu X; Zhang S
    Pigment Cell Melanoma Res; 2024 Mar; 37(2):247-258. PubMed ID: 37777339
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
    Weiss-Sadan T; Ge M; Hayashi M; Gohar M; Yao CH; de Groot A; Harry S; Carlin A; Fischer H; Shi L; Wei TY; Adelmann CH; Wolf K; Vornbäumen T; Dürr BR; Takahashi M; Richter M; Zhang J; Yang TY; Vijay V; Fisher DE; Hata AN; Haigis MC; Mostoslavsky R; Bardeesy N; Papagiannakopoulos T; Bar-Peled L
    Cell Metab; 2023 Mar; 35(3):487-503.e7. PubMed ID: 36841242
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Clinical Next-Generation Sequencing Panels Reveal Molecular Differences Between Merkel Cell Polyomavirus-Negative Merkel Cell Carcinomas and Neuroendocrine Carcinomas.
    Hartsough E; Mino-Kenudson M; Lennerz JK; Dias-Santagata D; Hoang MP
    Am J Clin Pathol; 2023 Apr; 159(4):395-406. PubMed ID: 36812363
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. NRF2 Enables EGFR Signaling in Melanoma Cells.
    Kreß JKC; Jessen C; Marquardt A; Hufnagel A; Meierjohann S
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33916908
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells.
    Schmidlin CJ; Tian W; Dodson M; Chapman E; Zhang DD
    Mol Carcinog; 2021 May; 60(5):331-341. PubMed ID: 33684228
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors.
    Rinaldi J; Sokol ES; Hartmaier RJ; Trabucco SE; Frampton GM; Goldberg ME; Albacker LA; Daemen A; Manning G
    PLoS One; 2020; 15(5):e0231999. PubMed ID: 32374727
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Electrophiles Against (skin) Diseases: More Than Nrf2.
    Hennig P; Fenini G; Di Filippo M; Beer HD
    Biomolecules; 2020 Feb; 10(2):. PubMed ID: 32053878
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Zerumbone Exhibits Antiphotoaging and Dermatoprotective Properties in Ultraviolet A-Irradiated Human skin Fibroblast Cells via the Activation of Nrf2/ARE Defensive Pathway.
    Hseu YC; Chang CT; Gowrisankar YV; Chen XZ; Lin HC; Yen HR; Yang HL
    Oxid Med Cell Longev; 2019; 2019():4098674. PubMed ID: 31814875
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Advances in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) research.
    Ooi A
    Semin Cancer Biol; 2020 Apr; 61():158-166. PubMed ID: 31689495
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. 17-Oxo-docosahexaenoic acid induces Nrf2-mediated expression of heme oxygenase-1 in mouse skin in vivo and in cultured murine epidermal cells.
    Jamil MU; Kim J; Yum HW; Kim SH; Kim SJ; Kim DH; Cho NC; Na HK; Surh YJ
    Arch Biochem Biophys; 2020 Jan; 679():108156. PubMed ID: 31629711
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity.
    Sobh A; Loguinov A; Yazici GN; Zeidan RS; Tagmount A; Hejazi NS; Hubbard AE; Zhang L; Vulpe CD
    Toxicol Sci; 2019 May; 169(1):108-121. PubMed ID: 30815697
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Sulforaphane as anticancer agent: A double-edged sword? Tricky balance between effects on tumor cells and immune cells.
    Liang J; Hänsch GM; Hübner K; Samstag Y
    Adv Biol Regul; 2019 Jan; 71():79-87. PubMed ID: 30528536
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of keap1-Nrf2 binding.
    Gacesa R; Lawrence KP; Georgakopoulos ND; Yabe K; Dunlap WC; Barlow DJ; Wells G; Young AR; Long PF
    Biochimie; 2018 Nov; 154():35-44. PubMed ID: 30071261
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Epigallocatechin-3-gallate partially restored redox homeostasis in arsenite-stressed keratinocytes.
    Sarkar N; Sinha D
    J Appl Toxicol; 2018 Aug; 38(8):1071-1080. PubMed ID: 29572906
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Marliolide inhibits skin carcinogenesis by activating NRF2/ARE to induce heme oxygenase-1.
    Lee J; Mailar K; Yoo OK; Choi WJ; Keum YS
    Eur J Med Chem; 2018 Apr; 150():113-126. PubMed ID: 29525432
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Curcumin Protects skin against UVB-Induced Cytotoxicity via the keap1-Nrf2 Pathway: The Use of a Microemulsion Delivery System.
    Ben Yehuda Greenwald M; Frušić-Zlotkin M; Soroka Y; Ben Sasson S; Bitton R; Bianco-Peled H; Kohen R
    Oxid Med Cell Longev; 2017; 2017():5205471. PubMed ID: 28757910
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Nrf2 activation as a key event triggered by skin sensitisers: The development of the stable KeratinoSens reporter gene assay.
    Natsch A; Emter R
    Altern Lab Anim; 2016 Oct; 44(5):443-451. PubMed ID: 27805827
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. An immunohistochemical study of NFE2L2, keap1 and 8-hydroxy-2'-deoxyguanosine and the EMT markers SNAI2, ZEB1 and TWIST1 in metastatic melanoma.
    Hintsala HR; Haapasaari KM; Soini Y; Karihtala P
    Histol Histopathol; 2017 Feb; 32(2):129-136. PubMed ID: 27170270
    [TBL] [Abstract] [Full Text] [Related]  


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