Terms: = Skin cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
275 results:
1. Immunohistochemical and Molecular Characteristics of Anogenital Papillary Hidradenomas.
Karpathiou G; Sim A; Picot T; Mekhzoumi K; Chauleur C; Péoc'h M
Am J Dermatopathol; 2024 Feb; 46(2):79-82. PubMed ID: 38055985
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2. Clinical, Morphologic, and Molecular Features of Benign and Intermediate-grade Melanocytic Tumors With Activating Mutations in map2k1.
Fumero-Velázquez M; Hagstrom M; Dhillon S; Geraminejad T; Olivares S; Donati M; Nosek D; Waldenbäck P; Kazakov D; Sheffield BS; Tron VA; Gerami P
Am J Surg Pathol; 2023 Dec; 47(12):1438-1448. PubMed ID: 37773074
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3. Determination of T-cell clonality and expression profiles of Toll-like receptors signaling pathway genes and related miRNAs in patients with mycosis fungoides.
Seçme M; Dodurga Y; Demirkan NÇ; Kaçar N; Günel NS; Açıkbaş İ
Gene; 2024 Jan; 891():147825. PubMed ID: 37748629
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4. Computational biology and in vitro studies for anticipating cancer-related molecular targets of sweet wormwood (Artemisia annua).
Dawood H; Celik I; Ibrahim RS
BMC Complement Med Ther; 2023 Sep; 23(1):312. PubMed ID: 37684586
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5. NTRK expression is common in xanthogranuloma and is associated with the solitary variant.
Umphress B; Kuhar M; Kowal R; Alomari AK; Baldridge LA; Ross AJ; Warren SJ
J Cutan Pathol; 2023 Nov; 50(11):991-1000. PubMed ID: 37580954
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6. map2k1-mutated melanocytic tumors have reproducible histopathologic features and share similarities with melanocytic tumors with BRAF V600E mutations.
Alomari AK; Harms PW; Andea AA; Warren SJ
J Cutan Pathol; 2023 Dec; 50(12):1083-1093. PubMed ID: 37565534
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7. Treatment experience with encorafenib plus binimetinib for BRAF V600-mutant metastatic melanoma: management insights for clinical practice.
Augustyn K; Joseph J; Patel AB; Razmandi A; Ali AN; Tawbi HA
Melanoma Res; 2023 Oct; 33(5):406-416. PubMed ID: 37534686
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8. Protein phosphatase 6 regulates trametinib sensitivity, a mitogen-activated protein kinase kinase (MEK) inhibitor, by regulating mek1/2-ERK1/2 signaling in canine melanoma cells.
Yamamoto M; Fujiwara N
J Vet Med Sci; 2023 Sep; 85(9):977-984. PubMed ID: 37495516
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9. Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Randic T; Magni S; Philippidou D; Margue C; Grzyb K; Preis JR; Wroblewska JP; Nazarov PV; Mittelbronn M; Frauenknecht KBM; Skupin A; Kreis S
Cell Rep; 2023 Jul; 42(7):112696. PubMed ID: 37379213
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10. Computational pharmacology profiling of borapetoside C against melanoma.
Bhattacharya K; Khanal P; Patil VS; Dwivedi PSR; Chanu NR; Chaudhary RK; Deka S; Chakraborty A
J Biomol Struct Dyn; 2024 Apr; 42(6):3233-3248. PubMed ID: 37203884
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11. Trametinib in Patients With
Wisinski KB; Flamand Y; Wilson MA; Luke JJ; Tawbi HA; Hong F; Mitchell EP; Zwiebel JA; Chen H; Gray RJ; Li S; McShane LM; Rubinstein LV; Patton D; Williams PM; Hamilton SR; Behrens RJ; Pennington KP; Conley BA; Arteaga CL; Harris LN; O'Dwyer PJ; Chen AP; Flaherty KT
JCO Precis Oncol; 2023 Apr; 7():e2200421. PubMed ID: 37053535
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12. Natural killer cells suppress human cutaneous squamous cell carcinoma cancer cell survival and tumor growth.
Adhikary G; Heipertz EL; Preradovic M; Chen X; Xu W; Newland JJ; Kaur N; Vemuri MC; Eckert RL
Mol Carcinog; 2023 Jun; 62(6):845-854. PubMed ID: 36994661
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13. Spitz Tumor With SQSTM1::NTRK2 Fusion: A Clinicopathological Study of 5 Cases.
Mansour B; Vanecek T; Kastnerova L; Nosek D; Kazakov DV; Donati M
Am J Dermatopathol; 2023 May; 45(5):306-310. PubMed ID: 36939120
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14. Optically activated mek1/2 inhibitors (Opti-MEKi) as potential antimelanoma agents.
Hao C; Li X; Wang Z; Liu L; He F; Pan Z
Eur J Med Chem; 2023 May; 251():115236. PubMed ID: 36924668
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15. Response and Resistance to Trametinib in map2k1-Mutant Triple-Negative Melanoma.
Krebs FS; Moura B; Missiaglia E; Aedo-Lopez V; Michielin O; Tsantoulis P; Bisig B; Trimech M; Zoete V; Homicsko K
Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901951
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16. Dabrafenib, alone or in combination with trametinib, in BRAF V600-mutated pediatric Langerhans cell histiocytosis.
Whitlock JA; Geoerger B; Dunkel IJ; Roughton M; Choi J; Osterloh L; Russo M; Hargrave D
Blood Adv; 2023 Aug; 7(15):3806-3815. PubMed ID: 36884302
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17. Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and mek1/2.
Wang P; Jia X; Lu B; Huang H; Liu J; Liu X; Wu Q; Hu Y; Li P; Wei H; Liu T; Zhao D; Zhang L; Tian X; Jiang Y; Qiao Y; Nie W; Ma X; Bai R; Peng C; Dong Z; Liu K
Signal Transduct Target Ther; 2023 Mar; 8(1):96. PubMed ID: 36872366
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18. An update on genomic aberrations in Spitz naevi and tumours.
Hagstrom M; Fumero-Velázquez M; Dhillon S; Olivares S; Gerami P
Pathology; 2023 Mar; 55(2):196-205. PubMed ID: 36631338
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19. Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma.
Takano K; Munehira Y; Hatanaka M; Murakami R; Shibata Y; Shida T; Takeuchi K; Takechi S; Tabata T; Shimada T; Kishikawa S; Matsui Y; Ubukata O; Seki T; Kaneta Y
Mol Cancer Ther; 2023 Mar; 22(3):317-332. PubMed ID: 36622773
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20. Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
Zob DL; Augustin I; Caba L; Panzaru MC; Popa S; Popa AD; Florea L; Gorduza EV
Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36614156
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