BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
12 results:

  • 1. RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway.
    Guo R; Lu SY; Ma JX; Wang QL; Zhang L; Tang LY; Shen Y; Shen CL; Wang JJ; Lu LM; Wang ZG; Zhang HX
    Hum Cell; 2022 Jul; 35(4):1071-1083. PubMed ID: 35416622
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility.
    Dobson SJ; Anene A; Boyne JR; Mankouri J; Macdonald A; Whitehouse A
    Biochem J; 2020 Jul; 477(14):2721-2733. PubMed ID: 32639530
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells.
    Srivastava RK; Li C; Khan J; Banerjee NS; Chow LT; Athar M
    Proc Natl Acad Sci U S A; 2019 Dec; 116(49):24583-24592. PubMed ID: 31732667
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Metastasis suppressor proteins in cutaneous squamous cell carcinoma.
    Bozdogan O; Vargel I; Cavusoglu T; Karabulut AA; Karahan G; Sayar N; Atasoy P; Yulug IG
    Pathol Res Pract; 2016 Jul; 212(7):608-15. PubMed ID: 27215390
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Differential expression patterns of metastasis suppressor proteins in basal cell carcinoma.
    Bozdogan O; Yulug IG; Vargel I; Cavusoglu T; Karabulut AA; Karahan G; Sayar N
    Int J Dermatol; 2015 Aug; 54(8):905-15. PubMed ID: 25428551
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3K, mkk4, and MKK7 in human melanoma.
    Song NR; Lee E; Byun S; Kim JE; Mottamal M; Park JH; Lim SS; Bode AM; Lee HJ; Lee KW; Dong Z
    Cancer Prev Res (Phila); 2013 Dec; 6(12):1293-303. PubMed ID: 24104352
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin.
    Prickett TD; Zerlanko B; Gartner JJ; Parker SCJ; Dutton-Regester K; Lin JC; Teer JK; Wei X; Jiang J; Nisc Comparative Sequencing Program ; Chen G; Davies MA; Gershenwald JE; Robinson W; Robinson S; Hayward NK; Rosenberg SA; Margulies EH; Samuels Y
    J Invest Dermatol; 2014 Feb; 134(2):452-460. PubMed ID: 24008424
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis.
    Kang NJ; Jung SK; Lee KW; Lee HJ
    Ann N Y Acad Sci; 2011 Jul; 1229():124-32. PubMed ID: 21793847
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Research on functional localization and cloning of metastasis suppressor genes].
    Liu H; Ye SL
    Ai Zheng; 2003 Nov; 22(11):1237-40. PubMed ID: 14613661
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Specific amino acid deficiency alters the expression of genes in human melanoma and other tumor cell lines.
    Meadows GG; Zhang H; Ge X
    J Nutr; 2001 Nov; 131(11 Suppl):3047S-50S. PubMed ID: 11694646
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma.
    Kunz M; Ibrahim S; Koczan D; Thiesen HJ; Köhler HJ; Acker T; Plate KH; Ludwig S; Rapp UR; Bröcker EB; van Muijen GN; Flory E; Gross G
    Cell Growth Differ; 2001 Mar; 12(3):137-45. PubMed ID: 11306514
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.
    Marti A; Luo Z; Cunningham C; Ohta Y; Hartwig J; Stossel TP; Kyriakis JM; Avruch J
    J Biol Chem; 1997 Jan; 272(5):2620-8. PubMed ID: 9006895
    [TBL] [Abstract] [Full Text] [Related]  


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