Terms: = Skin cancer AND MAPK1, MAPK2, 5594, ENSG00000100030, P28482, ERK2, p40, PRKM1, p38, p41, ERT1, p41mapk, PRKM2, P42MAPK, ERK AND Treatment
763 results:
1. Effect of NFX-179 MEK inhibitor on cutaneous neurofibromas in persons with neurofibromatosis type 1.
Sarin KY; Bradshaw M; O'Mara C; Shahryari J; Kincaid J; Kempers S; Tu JH; Dhawan S; DuBois J; Wilson D; Horwath P; de Souza MP; Powala C; Kochendoerfer GG; Plotkin SR; Webster GF; Le LQ
Sci Adv; 2024 May; 10(18):eadk4946. PubMed ID: 38691597
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2. ACA-28, an erk MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic cancer Cells.
Takasaki T; Hamabe Y; Touchi K; Khandakar GI; Ueda T; Okada H; Sakai K; Nishio K; Tanabe G; Sugiura R
Oxid Med Cell Longev; 2024; 2024():7683793. PubMed ID: 38500550
[TBL] [Abstract] [Full Text] [Related]
3. Antibody targeting of surface P-selectin glycoprotein ligand 1 leads to lymphoma apoptosis and tumorigenesis inhibition.
Pereira JL; Ferreira F; Dos Santos NR
Hematol Oncol; 2024 Mar; 42(2):e3257. PubMed ID: 38415859
[TBL] [Abstract] [Full Text] [Related]
4. A novel NIR fluorescent probe inhibits melanoma progression through apoptosis and erk/DRP1-mediated mitochondrial fission.
He Q; Li C; Ou Y; Pan Y; Yang X; Wang J; Liao H; Xiong X; Liu L; Sun C
Bioorg Chem; 2024 Apr; 145():107218. PubMed ID: 38377820
[TBL] [Abstract] [Full Text] [Related]
5. The CoREST repressor complex mediates phenotype switching and therapy resistance in melanoma.
Wu M; Hanly A; Gibson F; Fisher R; Rogers S; Park K; Zuger A; Kuang K; Kalin JH; Nocco S; Cole M; Xiao A; Agus F; Labadorf A; Beck S; Collard M; Cole PA; Alani RM
J Clin Invest; 2024 Feb; 134(6):. PubMed ID: 38300709
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6. Sanguinarine Triggers Apoptosis in Cutaneous Squamous Cell Carcinoma Cells through Reactive Oxygen Species-Dependent c-Jun N-Terminal Kinase Signaling Pathway.
Patil K; Khan AQ; Ahmad F; Kuttikrishnan S; Anver R; Mateo JM; Ahmad A; Bhat AA; Buddenkotte J; Steinhoff M; Uddin S
Front Biosci (Landmark Ed); 2024 Jan; 29(1):40. PubMed ID: 38287817
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7. Transcriptomic and proteomic analysis of tumor suppressive effects of GZ17-6.02 against mycosis fungoides.
Bordeaux ZA; Reddy SV; Choi J; Braun G; McKeel J; Lu W; Yossef SM; Ma EZ; West CE; Kwatra SG; Kwatra MM
Sci Rep; 2024 Jan; 14(1):1955. PubMed ID: 38263212
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8. Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies.
Bahar ME; Kim HJ; Kim DR
Signal Transduct Target Ther; 2023 Dec; 8(1):455. PubMed ID: 38105263
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9. STING promotes invasion and migration of uveal melanoma through p38‑MAPK signaling.
Zhou X; Meng F; Xu B; Ma R; Cheng Y; Wu J; Qian J
Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38099424
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10. erk hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma.
Jagirdar K; Portuallo ME; Wei M; Wilhide M; Bravo Narula JA; Robertson BM; Alicea GM; Aguh C; Xiao M; Godok T; Fingerman D; Brown GS; Herlyn M; Elad VM; Guo X; Toska E; Zabransky DJ; Wubbenhorst B; Nathanson KL; Kwatra S; Goyal Y; Ji H; Liu Q; Rebecca VW
Oncogene; 2024 Feb; 43(6):395-405. PubMed ID: 38066089
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11. Drug dependence in cancer is exploitable by optimally constructed treatment holidays.
Maltas J; Killarney ST; Singleton KR; Strobl MAR; Washart R; Wood KC; Wood KB
Nat Ecol Evol; 2024 Jan; 8(1):147-162. PubMed ID: 38012363
[TBL] [Abstract] [Full Text] [Related]
12. Preparation of
Qi J; Qi X; Chen H; Rui W
Anticancer Agents Med Chem; 2024; 24(2):132-145. PubMed ID: 37957869
[TBL] [Abstract] [Full Text] [Related]
13. Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
Wang R; Li J; Fu Y; Li Y; Qi Y; Li C; Gao F; Li C
Biochem Pharmacol; 2023 Dec; 218():115874. PubMed ID: 37866802
[TBL] [Abstract] [Full Text] [Related]
14. Viaminate Inhibits
Cao J; Xu M; Zhu L; Xiao S
Curr Drug Targets; 2023; 24(13):1055-1065. PubMed ID: 37861037
[TBL] [Abstract] [Full Text] [Related]
15. Piperlongumine induces apoptosis via the MAPK pathway and erk‑mediated autophagy in human melanoma cells.
Jeon SJ; Choi EY; Han EJ; Lee SW; Moon JM; Jung SH; Jung JY
Int J Mol Med; 2023 Dec; 52(6):. PubMed ID: 37830157
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16. Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling.
Bhattacharyya S; O-Sullivan I; Tu J; Chen Z; Tobacman JK
Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166913. PubMed ID: 37813168
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17. Biomineralized Polydopamine Nanoparticle-Based Sodium Alginate Hydrogels for Delivery of Anti-serine/Threonine Protein Kinase B-Rapidly Accelerated Fibrosarcoma siRNA for Metastatic Melanoma Therapy.
Lu J; Song J; Zhang P; Huang Y; Lu X; Dai H; Xi J
ACS Nano; 2023 Sep; 17(18):18318-18331. PubMed ID: 37690074
[TBL] [Abstract] [Full Text] [Related]
18. Ferulic Acid Induces Autophagy and Apoptosis in Colon cancer CT26 Cells via the MAPK Pathway.
Chen S; Zhao D; Luan C; Zheng J; Liu W; Feng Z; Luo R; Han X; Wang D
Molecules; 2023 Aug; 28(16):. PubMed ID: 37630266
[TBL] [Abstract] [Full Text] [Related]
19. Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced cancers.
Rustgi N; Maria A; Toumbacaris N; Zhao H; Kargus K; Bryant M; Waksmundzki A; Aricescu I; Lefkowitz RA; Li BT; Chou J; Capanu M; de Stanchina E; Misale S; Shia J; Yaeger R
Oncologist; 2024 Jan; 29(1):15-24. PubMed ID: 37616543
[TBL] [Abstract] [Full Text] [Related]
20. miR-224-5p acts as a tumour suppressor and reverses the resistance to BRAF inhibitor in melanoma through directly targeting PAK4 to block the MAPK pathway.
Liu Y; Ruan H; Lu F; Peng H; Luan W
Pathol Res Pract; 2023 Sep; 249():154772. PubMed ID: 37611431
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