Terms: = Skin cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
54 results:
1. A co-formulation of interferons alpha2b and gamma distinctively targets cell cycle in the glioblastoma-derived cell line U-87MG.
Miranda J; Vázquez-Blomquist D; Bringas R; Fernandez-de-Cossio J; Palenzuela D; Novoa LI; Bello-Rivero I
BMC Cancer; 2023 Aug; 23(1):806. PubMed ID: 37644431
[TBL] [Abstract] [Full Text] [Related]
2. Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma.
Huang R; Shen G; Ren Y; Zheng K; Wang J; Shi Y; Yin JC; Qin L; Zhang G; Zhao M; Su X; Li L; Wang F; Shao Y; Liu B; Zou Z
J Transl Med; 2023 Feb; 21(1):78. PubMed ID: 36739402
[TBL] [Abstract] [Full Text] [Related]
3. Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms: the KiKme study.
Grandt CL; Brackmann LK; Poplawski A; Schwarz H; Hummel-Bartenschlager W; Hankeln T; Kraemer C; Marini F; Zahnreich S; Schmitt I; Drees P; Mirsch J; Grabow D; Schmidberger H; Binder H; Hess M; Galetzka D; Marron M
Mol Med; 2022 Sep; 28(1):105. PubMed ID: 36068491
[TBL] [Abstract] [Full Text] [Related]
4. Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
Zhou S; Li P; Qin L; Huang S; Dang N
Exp Dermatol; 2022 Oct; 31(10):1563-1578. PubMed ID: 35730240
[TBL] [Abstract] [Full Text] [Related]
5. ROR2 increases the chemoresistance of melanoma by regulating p53 and Bcl2-family proteins via ERK hyperactivation.
Castro MV; Barbero GA; Máscolo P; Ramos R; Quezada MJ; Lopez-Bergami P
Cell Mol Biol Lett; 2022 Mar; 27(1):23. PubMed ID: 35260073
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6.
Merecz-Sadowska A; Sitarek P; Śliwiński T; Zajdel K; Malinowska K; Zielińska-Bliźniewska H; Kucharska E; Zajdel R
Curr Pharm Biotechnol; 2022; 23(11):1383-1395. PubMed ID: 35249478
[TBL] [Abstract] [Full Text] [Related]
7. IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma.
Song D; Cismas S; Crudden C; Trocme E; Worrall C; Suleymanova N; Lin T; Zheng H; Seregard S; Girnita A; Girnita L
Oncogene; 2022 Jan; 41(4):600-611. PubMed ID: 34785779
[TBL] [Abstract] [Full Text] [Related]
8. Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways.
Jamal SME; Alamodi A; Wahl RU; Grada Z; Shareef MA; Hassan SY; Murad F; Hassan SL; Santourlidis S; Gomez CR; Haikel Y; Megahed M; Hassan M
Oncogene; 2020 Aug; 39(32):5468-5478. PubMed ID: 32616888
[TBL] [Abstract] [Full Text] [Related]
9. Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports.
Chen S; Zhang X; Shen L; Qi H; Ma W; Cao F; Xie L; Song Z; Wu Y; Li D; Wen X; Fan W
J Cancer Res Ther; 2020; 16(2):387-392. PubMed ID: 32474528
[TBL] [Abstract] [Full Text] [Related]
10. Targeting p63 Upregulation Abrogates Resistance to MAPK Inhibitors in Melanoma.
Patel A; Garcia LF; Mannella V; Gammon L; Borg TM; Maffucci T; Scatolini M; Chiorino G; Vergani E; Rodolfo M; Maurichi A; Posch C; Matin RN; Harwood CA; Bergamaschi D
Cancer Res; 2020 Jun; 80(12):2676-2688. PubMed ID: 32291316
[TBL] [Abstract] [Full Text] [Related]
11. Metastatic Melanoma Patient-Derived Xenografts Respond to mdm2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition.
Shattuck-Brandt RL; Chen SC; Murray E; Johnson CA; Crandall H; O'Neal JF; Al-Rohil RN; Nebhan CA; Bharti V; Dahlman KB; Ayers GD; Yan C; Kelley MC; Kauffmann RM; Hooks M; Grau A; Johnson DB; Vilgelm AE; Richmond A
Clin Cancer Res; 2020 Jul; 26(14):3803-3818. PubMed ID: 32234759
[TBL] [Abstract] [Full Text] [Related]
12. WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5-mdm2-p53 pathway.
Li Y; Zhou Y; Li B; Chen F; Shen W; Lu Y; Zhong C; Zhang C; Xie H; Katanaev VL; Jia L
Oncogene; 2020 Mar; 39(13):2741-2755. PubMed ID: 32005977
[TBL] [Abstract] [Full Text] [Related]
13. Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and mdm2 as a potential therapy in uveal melanoma.
Decaudin D; Frisch Dit Leitz E; Nemati F; Tarin M; Naguez A; Zerara M; Marande B; Vivet-Noguer R; Halilovic E; Fabre C; Jochemsen A; Roman-Roman S; Alsafadi S
Eur J Cancer; 2020 Feb; 126():93-103. PubMed ID: 31927215
[TBL] [Abstract] [Full Text] [Related]
14. Immunogenetic effects of low dose (CEM43 30) magnetic nanoparticle hyperthermia and radiation in melanoma cells.
Duval KEA; Vernice NA; Wagner RJ; Fiering SN; Petryk JD; Lowry GJ; Tau SS; Yin J; Houde GR; Chaudhry AS; Hoopes PJ
Int J Hyperthermia; 2019 Nov; 36(sup1):37-46. PubMed ID: 31795829
[No Abstract] [Full Text] [Related]
15. Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53.
Park KH; Choi JH; Song YS; Kim GC; Hong JW
BMC Complement Altern Med; 2019 Aug; 19(1):231. PubMed ID: 31462222
[TBL] [Abstract] [Full Text] [Related]
16. Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3.
Park JE; Kim DH; Ha E; Choi SM; Choi JS; Chun KS; Joo SH
Chem Biol Interact; 2019 Oct; 312():108799. PubMed ID: 31433961
[TBL] [Abstract] [Full Text] [Related]
17. mdm2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Vilgelm AE; Saleh N; Shattuck-Brandt R; Riemenschneider K; Slesur L; Chen SC; Johnson CA; Yang J; Blevins A; Yan C; Johnson DB; Al-Rohil RN; Halilovic E; Kauffmann RM; Kelley M; Ayers GD; Richmond A
Sci Transl Med; 2019 Aug; 11(505):. PubMed ID: 31413145
[TBL] [Abstract] [Full Text] [Related]
18. Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells.
Proto MC; Fiore D; Forte G; Cuozzo P; Ramunno A; Fattorusso C; Gazzerro P; Pascale M; Franceschelli S
Invest New Drugs; 2020 Jun; 38(3):634-649. PubMed ID: 31240514
[TBL] [Abstract] [Full Text] [Related]
19. Benzimidazoles Downregulate mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells.
Mrkvová Z; Uldrijan S; Pombinho A; Bartůněk P; Slaninová I
Molecules; 2019 Jun; 24(11):. PubMed ID: 31181622
[TBL] [Abstract] [Full Text] [Related]
20. Analysis of Mucosal Melanoma Whole-Genome Landscapes Reveals Clinically Relevant Genomic Aberrations.
Zhou R; Shi C; Tao W; Li J; Wu J; Han Y; Yang G; Gu Z; Xu S; Wang Y; Wang L; Wang Y; Zhou G; Zhang C; Zhang Z; Sun S
Clin Cancer Res; 2019 Jun; 25(12):3548-3560. PubMed ID: 30782616
[TBL] [Abstract] [Full Text] [Related]
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