Terms: = Skin cancer AND PLCG1, PLC1, 5335, ENSG00000124181, PLC-II, Plcg1, PLCgamma1, PLC148
20 results:
1. Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases.
Peng WY; Abere B; Shi H; Toland S; Smithgall TE; Moore PS; Chang Y
Proc Natl Acad Sci U S A; 2023 Dec; 120(51):e2316467120. PubMed ID: 38079542
[TBL] [Abstract] [Full Text] [Related]
2. Primary cutaneous peripheral T-cell lymphomas with a T-follicular helper phenotype: an integrative clinical, pathological and molecular case series study.
Wang L; Rocas D; Dalle S; Sako N; Pelletier L; Martin N; Dupuy A; Tazi N; Balme B; Vergier B; Beylot-Barry M; Carlotti A; Bagot M; Battistella M; Chaby G; Ingen-Housz-Oro S; Gaulard P; Ortonne N
Br J Dermatol; 2022 Dec; 187(6):970-980. PubMed ID: 35895386
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3. EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines.
Te Molder L; Kreft M; Heemskerk N; Schuring J; de Pereda JM; Wilhelmsen K; Sonnenberg A
Sci Rep; 2021 Apr; 11(1):8675. PubMed ID: 33883672
[TBL] [Abstract] [Full Text] [Related]
4. Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group.
Beltzung F; Ortonne N; Pelletier L; Beylot-Barry M; Ingen-Housz-Oro S; Franck F; Pereira B; Godfraind C; Delfau MH; D'Incan M; Vergier B
Am J Surg Pathol; 2020 Jul; 44(7):862-872. PubMed ID: 32271188
[TBL] [Abstract] [Full Text] [Related]
5. High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations.
Fernandez-Pol S; Costa HA; Steiner DF; Ma L; Merker JD; Kim YH; Arber DA; Kim J
Appl Immunohistochem Mol Morphol; 2019; 27(10):740-748. PubMed ID: 31702703
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6. Frequent and Persistent plcg1 Mutations in Sézary Cells Directly Enhance PLCγ1 Activity and Stimulate NFκB, AP-1, and NFAT Signaling.
Patel VM; Flanagan CE; Martins M; Jones CL; Butler RM; Woollard WJ; Bakr FS; Yoxall A; Begum N; Katan M; Whittaker SJ; Mitchell TJ
J Invest Dermatol; 2020 Feb; 140(2):380-389.e4. PubMed ID: 31376383
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7. Advanced-stage mycosis fungoides: role of the signal transducer and activator of transcription 3, nuclear factor-κB and nuclear factor of activated T cells pathways.
Pérez C; Mondéjar R; García-Díaz N; Cereceda L; León A; Montes S; Durán Vian C; Pérez Paredes MG; González-Morán A; Alegre de Miguel V; Sanz Anquela JM; Frias J; Limeres MA; González LM; Martín Dávila F; Beltrán M; Mollejo M; Méndez JR; González MA; González García J; López R; Gómez A; Izquierdo F; Ramos R; Camacho C; Rodriguez-Pinilla SM; Martínez N; Vaqué JP; Ortiz-Romero PL; Piris MA
Br J Dermatol; 2020 Jan; 182(1):147-155. PubMed ID: 31049933
[TBL] [Abstract] [Full Text] [Related]
8. Cost Estimate of Immune-Related Adverse Reactions Associated with Innovative Treatments of Metastatic Melanoma.
Mennini FS; Bini C; Marcellusi A; Del Vecchio M
Clin Drug Investig; 2018 Oct; 38(10):967-976. PubMed ID: 30143953
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9. Oncogenomic analysis identifies novel biomarkers for tumor stage mycosis fungoides.
Dong Z; Zhu X; Li Y; Gan L; Chen H; Zhang W; Sun J
Medicine (Baltimore); 2018 May; 97(21):e10871. PubMed ID: 29794791
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10. UCP2 upregulation promotes PLCγ-1 signaling during skin cell transformation.
Sreedhar A; Lefort J; Petruska P; Gu X; Shi R; Miriyala S; Panchatcharam M; Zhao Y
Mol Carcinog; 2017 Oct; 56(10):2290-2300. PubMed ID: 28574619
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11. Sézary Syndrome: Translating Genetic Diversity into Personalized Medicine.
Chevret E; Merlio JP
J Invest Dermatol; 2016 Jul; 136(7):1319-1324. PubMed ID: 27342034
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12. A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma cancer Cell Invasion.
Raimondi C; Calleja V; Ferro R; Fantin A; Riley AM; Potter BV; Brennan CH; Maffucci T; Larijani B; Falasca M
Sci Rep; 2016 May; 6():26142. PubMed ID: 27199173
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13. Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes.
Wang L; Ni X; Covington KR; Yang BY; Shiu J; Zhang X; Xi L; Meng Q; Langridge T; Drummond J; Donehower LA; Doddapaneni H; Muzny DM; Gibbs RA; Wheeler DA; Duvic M
Nat Genet; 2015 Dec; 47(12):1426-34. PubMed ID: 26551670
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14. Phospholipase C gamma 1 (plcg1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma.
Prenen H; Smeets D; Mazzone M; Lambrechts D; Sagaert X; Sciot R; Debiec-Rychter M
Oncotarget; 2015 Nov; 6(34):36418-25. PubMed ID: 26474454
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15. plcg1 Gene Mutations in Cutaneous T-Cell Lymphomas Revisited.
Tensen CP
J Invest Dermatol; 2015 Sep; 135(9):2153-2154. PubMed ID: 26269406
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16. c-CBL E3 ubiquitin ligase is overexpressed in cutaneous T-cell lymphoma: its inhibition promotes activation-induced cell death.
Wu J; Salva KA; Wood GS
J Invest Dermatol; 2015 Mar; 135(3):861-868. PubMed ID: 25140833
[TBL] [Abstract] [Full Text] [Related]
17. plcg1 mutations in cutaneous T-cell lymphomas.
Vaqué JP; Gómez-López G; Monsálvez V; Varela I; Martínez N; Pérez C; Domínguez O; Graña O; Rodríguez-Peralto JL; Rodríguez-Pinilla SM; González-Vela C; Rubio-Camarillo M; Martín-Sánchez E; Pisano DG; Papadavid E; Papadaki T; Requena L; García-Marco JA; Méndez M; Provencio M; Hospital M; Suárez-Massa D; Postigo C; San Segundo D; López-Hoyos M; Ortiz-Romero PL; Piris MA; Sánchez-Beato M
Blood; 2014 Mar; 123(13):2034-43. PubMed ID: 24497536
[TBL] [Abstract] [Full Text] [Related]
18. CXCR4 pathway associated with family history of melanoma.
Li WQ; Han J; Widlund HR; Correll M; Wang YE; Quackenbush J; Mihm MC; Canales AL; Wu S; Golub T; Hoshida Y; Hunter DJ; Murphy G; Kupper TS; Qureshi AA
Cancer Causes Control; 2014 Jan; 25(1):125-32. PubMed ID: 24158781
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19. Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death.
Klemke CD; Brenner D; Weiss EM; Schmidt M; Leverkus M; Gülow K; Krammer PH
Cancer Res; 2009 May; 69(10):4175-83. PubMed ID: 19435902
[TBL] [Abstract] [Full Text] [Related]
20. Ircinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells.
Choi HJ; Choi YH; Yee SB; Im E; Jung JH; Kim ND
Mol Carcinog; 2005 Nov; 44(3):162-73. PubMed ID: 16163705
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