BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND PTPN11, CFC, Q06124, 5781, ENSG00000179295, SHP2, MGC14433, SHP-2, BPTP3, PTP-1D, SH-PTP3, NS1, SH-PTP2, PTP2C
100 results:

  • 1. Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling.
    Bhattacharyya S; O-Sullivan I; Tu J; Chen Z; Tobacman JK
    Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166913. PubMed ID: 37813168
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Dysregulated ceramides metabolism via ptpn11 exposes a metabolic vulnerability to breast cancer metastasis.
    Qiao S; Wang T; Wang H
    Med Oncol; 2023 Sep; 40(11):310. PubMed ID: 37773553
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Tumor Cell-Autonomous shp2 Contributes to Immune Suppression in Metastatic Breast cancer.
    Chen H; Cresswell GM; Libring S; Ayers MG; Miao J; Zhang ZY; Solorio L; Ratliff TL; Wendt MK
    Cancer Res Commun; 2022 Oct; 2(10):1104-1118. PubMed ID: 36969745
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. ptpn11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma.
    Polubothu S; Bender N; Muthiah S; Zecchin D; Demetriou C; Martin SB; Malhotra S; Travnickova J; Zeng Z; Böhm M; Barbarot S; Cottrell C; Davies O; Baselga E; Burrows NP; Carmignac V; Diaz JS; Fink C; Haenssle HA; Happle R; Harland M; Majerowski J; Vabres P; Vincent M; Newton-Bishop JA; Bishop DT; Siegel D; Patton EE; Topf M; Rajan N; Drolet B; Kinsler VA
    J Invest Dermatol; 2023 Jun; 143(6):1042-1051.e3. PubMed ID: 36566878
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of shp2 phosphatase.
    Ye W; Liu Y; Ren Q; Liao T; Chen Y; Chen D; Wang S; Yao L; Jia Y; Zhao C; Zhou Z
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1495-1513. PubMed ID: 35635145
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Gene Expression Profiling of Mycosis Fungoides in Early and Tumor Stage-A Proof-of-Concept Study Using Laser Capture/Single Cell Microdissection and NanoString Analysis.
    Lai J; Li J; Gniadecki R; Lai R
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831413
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Influenza virus vector ins1 expressing bovine papillomavirus 1 (BPV1) antigens efficiently induces tumour regression in equine sarcoid patients.
    Jindra C; Hainisch EK; Rümmele A; Wolschek M; Muster T; Brandt S
    PLoS One; 2021; 16(11):e0260155. PubMed ID: 34797850
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Leopard syndrome: the potential cardiac defect underlying skin phenotypes.
    Yue X; Zhao X; Dai Y; Yu L
    Hereditas; 2021 Sep; 158(1):34. PubMed ID: 34488904
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genomic data from NSCLC tumors reveals correlation between shp-2 activity and PD-L1 expression and suggests synergy in combining shp-2 and PD-1/PD-L1 inhibitors.
    Toral KJ; Wuenschel MA; Black EP
    PLoS One; 2021; 16(8):e0256416. PubMed ID: 34437586
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3.
    Montaudié H; Sormani L; Dadone-Montaudié B; Heim M; Cardot-Leccia N; Tulic MK; Beranger G; Gay AS; Debayle D; Cheli Y; Raymond JH; Sohier P; Petit V; Rocchi S; Gesbert F; Larue L; Passeron T
    J Invest Dermatol; 2022 Feb; 142(2):425-434. PubMed ID: 34310951
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade.
    Okoye IS; Xu L; Walker J; Elahi S
    Cancer Immunol Immunother; 2020 Aug; 69(8):1423-1436. PubMed ID: 32246174
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. [
    Xu HY; Yuan YY; Dai P
    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2019 Sep; 33(9):830-834. PubMed ID: 31446698
    [No Abstract]    [Full Text] [Related]  

  • 13. Siglec-9 Regulates an Effector Memory CD8
    Haas Q; Boligan KF; Jandus C; Schneider C; Simillion C; Stanczak MA; Haubitz M; Seyed Jafari SM; Zippelius A; Baerlocher GM; Läubli H; Hunger RE; Romero P; Simon HU; von Gunten S
    Cancer Immunol Res; 2019 May; 7(5):707-718. PubMed ID: 30988027
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Trametinib for progressive pediatric low-grade gliomas.
    Kondyli M; Larouche V; Saint-Martin C; Ellezam B; Pouliot L; Sinnett D; Legault G; Crevier L; Weil A; Farmer JP; Jabado N; Perreault S
    J Neurooncol; 2018 Nov; 140(2):435-444. PubMed ID: 30097824
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Synthesis, Characterization, and Initial Biological Evaluation of [
    Gao F; Sihver W; Bergmann R; Belter B; Bolzati C; Salvarese N; Steinbach J; Pietzsch J; Pietzsch HJ
    ChemMedChem; 2018 Jun; 13(11):1146-1158. PubMed ID: 29659163
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. SLAM family member 8 is involved in oncogenic KIT-mediated signalling in human mastocytosis.
    Sugimoto A; Kataoka TR; Ueshima C; Takei Y; Kitamura K; Hirata M; Nomura T; Haga H
    Exp Dermatol; 2018 Jun; 27(6):641-646. PubMed ID: 29498772
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. High response rate to PD-1 blockade in desmoplastic melanomas.
    Eroglu Z; Zaretsky JM; Hu-Lieskovan S; Kim DW; Algazi A; Johnson DB; Liniker E; Ben Kong ; Munhoz R; Rapisuwon S; Gherardini PF; Chmielowski B; Wang X; Shintaku IP; Wei C; Sosman JA; Joseph RW; Postow MA; Carlino MS; Hwu WJ; Scolyer RA; Messina J; Cochran AJ; Long GV; Ribas A
    Nature; 2018 Jan; 553(7688):347-350. PubMed ID: 29320474
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure.
    Haugh AM; Zhang B; Quan VL; Garfield EM; Bubley JA; Kudalkar E; Verzi AE; Walton K; VandenBoom T; Merkel EA; Lee CY; Tan T; Isales MC; Kong BY; Wenzel AT; Bunick CG; Choi J; Sosman J; Gerami P
    J Invest Dermatol; 2018 Feb; 138(2):384-393. PubMed ID: 28870692
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [Multiple granular cell tumours in a patient with Noonan's syndrome and juvenile myelomonocytic leukaemia].
    Castagna J; Clerc J; Dupond AS; Laresche C
    Ann Dermatol Venereol; 2017 Nov; 144(11):705-711. PubMed ID: 28728859
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Familial melanoma-astrocytoma syndrome: synchronous diffuse astrocytoma and pleomorphic xanthoastrocytoma in a patient with germline CDKN2A/B deletion and a significant family history.
    Chan AK; Han SJ; Choy W; Beleford D; Aghi MK; Berger MS; Shieh JT; Bollen AW; Perry A; Phillips JJ; Butowski N; Solomon DA
    Clin Neuropathol; 2017; 36(5):213-221. PubMed ID: 28699883
    [TBL] [Abstract] [Full Text] [Related]  


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