Terms: = Skin cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
43 results:
1. Taxifolin inhibits melanoma proliferation/migration impeding USP18/rac1/JNK/β-catenin oncogenic signaling.
Xu L; Zhang L; Zhang S; Yang J; Zhu A; Sun J; Kalvakolanu DV; Cong X; Zhang J; Tang J; Guo B
Phytomedicine; 2024 Jan; 123():155199. PubMed ID: 37995531
[TBL] [Abstract] [Full Text] [Related]
2. Primary mucosal melanomas of the urogenital tract: a clinical, pathological, and genetic nationwide survey of Danish patients 1990-2019.
Znaider VK; Mikkelsen LH; Jensen CFS; Sønksen J; Heegaard S
Scand J Urol; 2023 Aug; 58():52-59. PubMed ID: 37635444
[TBL] [Abstract] [Full Text] [Related]
3. A comprehensive signature based on endoplasmic reticulum stress-related genes in predicting prognosis and immunotherapy response in melanoma.
Liu L; Yao D; Chen Z; Duan S
Sci Rep; 2023 May; 13(1):8232. PubMed ID: 37217516
[TBL] [Abstract] [Full Text] [Related]
4. Whole-Exome Sequencing and cfDNA Analysis Uncover Genetic Determinants of Melanoma Therapy Response in a Real-World Setting.
Vanni I; Pastorino L; Tanda ET; Andreotti V; Dalmasso B; Solari N; Mascherini M; Cabiddu F; Guadagno A; Coco S; Allavena E; Bruno W; Pietra G; Croce M; Gangemi R; Piana M; Zoppoli G; Ferrando L; Spagnolo F; Queirolo P; Ghiorzo P
Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901733
[TBL] [Abstract] [Full Text] [Related]
5. Characterisation and outcome of rac1 mutated melanoma.
Lodde GC; Jansen P; Herbst R; Terheyden P; Utikal J; Pföhler C; Ulrich J; Kreuter A; Mohr P; Gutzmer R; Meier F; Dippel E; Weichenthal M; Sucker A; Placke JM; Zaremba A; Albrecht LJ; Kowall B; Galetzka W; Becker JC; Tasdogan A; Zimmer L; Livingstone E; Hadaschik E; Schadendorf D; Ugurel S; Griewank K
Eur J Cancer; 2023 Apr; 183():1-10. PubMed ID: 36773463
[TBL] [Abstract] [Full Text] [Related]
6. Cutaneous squamous cell carcinoma in an autosomal-recessive Adams-Oliver syndrome patient with a novel frameshift pathogenic variant in the EOGT gene.
Lukas ML; Harald G; Sanz J; Trippel M; Sabina G; Jochen R
Am J Med Genet A; 2022 Nov; 188(11):3318-3323. PubMed ID: 36059114
[TBL] [Abstract] [Full Text] [Related]
7. A distinct pattern of growth and rac1 signaling in melanoma brain metastasis cells.
Stejerean-Todoran I; Gimotty PA; Watters A; Brafford P; Krepler C; Godok T; Li H; Bonilla Del Rio Z; Zieseniss A; Katschinski DM; Sertel SM; Rizzoli SO; Garman B; Nathanson KL; Xu X; Chen Q; Oswald JH; Lotem M; Mills GB; Davies MA; Schön MP; Bogeski I; Herlyn M; Vultur A
Neuro Oncol; 2023 Apr; 25(4):674-686. PubMed ID: 36054930
[TBL] [Abstract] [Full Text] [Related]
8. Monensin synergizes with chemotherapy in uveal melanoma through suppressing RhoA.
Zeng C; Long M; Lu Y
Immunopharmacol Immunotoxicol; 2023 Feb; 45(1):35-42. PubMed ID: 36043455
[TBL] [Abstract] [Full Text] [Related]
9. FMRP ligand circZNF609 destabilizes rac1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma.
Shang Q; Du H; Wu X; Guo Q; Zhang F; Gong Z; Jiao T; Guo J; Kong Y
J Exp Clin Cancer Res; 2022 May; 41(1):170. PubMed ID: 35534866
[TBL] [Abstract] [Full Text] [Related]
10. Fermitin family member 2 promotes melanoma progression by enhancing the binding of p-α-Pix to rac1 to activate the MAPK pathway.
Huang S; Deng W; Wang P; Yan Y; Xie C; Cao X; Chen M; Zhang C; Shi D; Dong Y; Cheng P; Xu H; Zhu W; Hu Z; Tang B; Zhu J
Oncogene; 2021 Sep; 40(37):5626-5638. PubMed ID: 34321603
[TBL] [Abstract] [Full Text] [Related]
11. High tumour mutational burden and EGFR/MAPK pathway activation are therapeutic targets in metastatic porocarcinoma.
Westphal D; Garzarolli M; Sergon M; Horak P; Hutter B; Becker JC; Wiegel M; Maczey E; Blum S; Grosche-Schlee S; Rütten A; Ugurel S; Stenzinger A; Glimm H; Aust D; Baretton G; Beissert S; Fröhling S; Redler S; Surowy H; Meier F
Br J Dermatol; 2021 Dec; 185(6):1186-1199. PubMed ID: 34185311
[TBL] [Abstract] [Full Text] [Related]
12. A new synthetic antitumor naphthoquinone induces ROS-mediated apoptosis with activation of the JNK and p38 signaling pathways.
de Almeida PDO; Dos Santos Barbosa Jobim G; Dos Santos Ferreira CC; Rocha Bernardes L; Dias RB; Schlaepfer Sales CB; Valverde LF; Rocha CAG; Soares MBP; Bezerra DP; de Carvalho da Silva F; Cardoso MFDC; Ferreira VF; Brito LF; Pires de Sousa L; de Vasconcellos MC; Lima ES
Chem Biol Interact; 2021 Jul; 343():109444. PubMed ID: 33939975
[TBL] [Abstract] [Full Text] [Related]
13. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation.
Amado-Azevedo J; van Stalborch AD; Valent ET; Nawaz K; van Bezu J; Eringa EC; Hoevenaars FPM; De Cuyper IM; Hordijk PL; van Hinsbergh VWM; van Nieuw Amerongen GP; Aman J; Margadant C
Angiogenesis; 2021 Aug; 24(3):677-693. PubMed ID: 33770321
[TBL] [Abstract] [Full Text] [Related]
14. Anticancer Potential of Aguerin B, a Sesquiterpene Lactone Isolated from
Amini E; Nabiuni M; Behzad SB; Seyfi D; Eisvand F; Sahebkar A; Shakeri A
Recent Pat Anticancer Drug Discov; 2020; 15(2):165-173. PubMed ID: 32660408
[TBL] [Abstract] [Full Text] [Related]
15. Verification of EZH2 as a druggable target in metastatic uveal melanoma.
Jin B; Zhang P; Zou H; Ye H; Wang Y; Zhang J; Yang H; Pan J
Mol Cancer; 2020 Mar; 19(1):52. PubMed ID: 32127003
[TBL] [Abstract] [Full Text] [Related]
16. Genetic Profiling of Advanced Melanoma: Candidate Mutations for Predicting Sensitivity and Resistance to Targeted Therapy.
Olbryt M; Pigłowski W; Rajczykowski M; Pfeifer A; Student S; Fiszer-Kierzkowska A
Target Oncol; 2020 Feb; 15(1):101-113. PubMed ID: 31980996
[TBL] [Abstract] [Full Text] [Related]
17. Resveratrol inhibits the proliferation of melanoma cells by modulating cell cycle.
Yang HZ; Zhang J; Zeng J; Liu S; Zhou F; Zhang F; Giampieri F; Cianciosi D; Forbes-Hernandez TY; Ansary J; Gil E; Chen R; Battino M
Int J Food Sci Nutr; 2020 Feb; 71(1):84-93. PubMed ID: 31154861
[TBL] [Abstract] [Full Text] [Related]
18. Cellular and molecular mechanisms of curcumin in prevention and treatment of disease.
Patel SS; Acharya A; Ray RS; Agrawal R; Raghuwanshi R; Jain P
Crit Rev Food Sci Nutr; 2020; 60(6):887-939. PubMed ID: 30632782
[TBL] [Abstract] [Full Text] [Related]
19. Chemotherapy induced PRL3 expression promotes cancer growth via plasma membrane remodeling and specific alterations of caveolae-associated signaling.
Csoboz B; Gombos I; Tatrai E; Tovari J; Kiss AL; Horvath I; Vigh L
Cell Commun Signal; 2018 Aug; 16(1):51. PubMed ID: 30157875
[TBL] [Abstract] [Full Text] [Related]
20. The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations.
Berger M; Richtig G; Kashofer K; Aigelsreiter A; Richtig E
G Ital Dermatol Venereol; 2018 Jun; 153(3):349-360. PubMed ID: 29600692
[TBL] [Abstract] [Full Text] [Related]
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