BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND SYK, P43405, 6850, ENSG00000165025
24 results:

  • 1. Immunomodulatory role of spleen tyrosine kinase in chronic inflammatory and autoimmune diseases.
    Zhou Y; Zhang Y; Yu W; Qin Y; He H; Dai F; Wang Y; Zhu F; Zhou G
    Immun Inflamm Dis; 2023 Jul; 11(7):e934. PubMed ID: 37506139
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition.
    Ferguson R; Chat V; Morales L; Simpson D; Monson KR; Cohen E; Zusin S; Madonna G; Capone M; Simeone E; Pavlick A; Luke JJ; Gajewski TF; Osman I; Ascierto P; Weber J; Kirchhoff T
    Eur J Cancer; 2023 Aug; 189():112923. PubMed ID: 37301715
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms.
    Jaeger A; Gambheer SMM; Sun X; Chernyakov D; Skorobohatko O; Mack T; Kissel S; Pfeifer D; Zeiser R; Fisch P; Andrieux G; Bräuer-Hartmann D; Bauer M; Schulze S; Follo M; Boerries M; von Bubnoff N; Miething C; Hidalgo JV; Klein C; Weber T; Wickenhauser C; Binder M; Dierks C
    Blood; 2023 Jun; 141(23):2824-2840. PubMed ID: 36696631
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Loss of NF1 in Melanoma Confers Sensitivity to syk Kinase Inhibition.
    Abecunas C; Whitehead CE; Ziemke EK; Baumann DG; Frankowski-McGregor CL; Sebolt-Leopold JS; Fallahi-Sichani M
    Cancer Res; 2023 Jan; 83(2):316-331. PubMed ID: 36409827
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Cartilage oligomeric matrix protein acts as a molecular biomarker in multiple cancer types.
    Guo B; Wang Y; Liu W; Zhang S
    Clin Transl Oncol; 2023 Feb; 25(2):535-554. PubMed ID: 36255654
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. American Joint Committee on cancer Tumor Staging System Predicts the Outcome and Metastasis Pattern in Conjunctival Melanoma.
    Jia S; Zhu T; Shi H; Zong C; Bao Y; Wen X; Ge S; Ruan J; Xu S; Jia R; Fan X
    Ophthalmology; 2022 Jul; 129(7):771-780. PubMed ID: 35245602
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Kinase Inhibition as Treatment for Acute and Chronic Graft-
    Braun LM; Zeiser R
    Front Immunol; 2021; 12():760199. PubMed ID: 34868001
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of
    Walker AR; Byrd JC; Blachly JS; Bhatnagar B; Mims AS; Orwick S; Lin TL; Crosswell HE; Zhang D; Minden MD; Munugalavadla V; Long L; Liu J; Pan Y; Oellerich T; Serve H; Rao AV; Blum WG
    Clin Cancer Res; 2020 Nov; 26(22):5852-5859. PubMed ID: 32820015
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The Mincle/syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages.
    Li C; Xue VW; Wang QM; Lian GY; Huang XR; Lee TL; To KF; Tang PM; Lan HY
    Cancer Immunol Res; 2020 Aug; 8(8):1004-1017. PubMed ID: 32532809
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The suppressive effect of dabrafenib, a therapeutic agent for metastatic melanoma, in IgE-mediated allergic inflammation.
    Choi YA; Lee S; Choi JK; Kang BC; Kim MJ; Dhakal H; Kwon TK; Khang D; Kim SH
    Int Immunopharmacol; 2020 Jun; 83():106398. PubMed ID: 32197228
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Silencing of microRNA-27a facilitates autophagy and apoptosis of melanoma cells through the activation of the syk-dependent mTOR signaling pathway.
    Tang H; Xu X; Xiao W; Liao Y; Xiao X; Li L; Li K; Jia X; Feng H
    J Cell Biochem; 2019 Aug; 120(8):13262-13274. PubMed ID: 30994959
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Biologics for chronic inflammatory skin diseases: an update for the clinician.
    Yao Y; Ravn Jørgensen AH; Thomsen SF
    J Dermatolog Treat; 2020 Mar; 31(2):108-130. PubMed ID: 30827126
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Loss of SLC25A11 causes suppression of NSCLC and melanoma tumor formation.
    Lee JS; Lee H; Lee S; Kang JH; Lee SH; Kim SG; Cho ES; Kim NH; Yook JI; Kim SY
    EBioMedicine; 2019 Feb; 40():184-197. PubMed ID: 30686754
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. RAC1 P29S regulates PD-L1 expression in melanoma.
    Vu HL; Rosenbaum S; Purwin TJ; Davies MA; Aplin AE
    Pigment Cell Melanoma Res; 2015 Sep; 28(5):590-8. PubMed ID: 26176707
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. BRAF inhibitor-associated ERK activation drives development of chronic lymphocytic leukemia.
    Yaktapour N; Meiss F; Mastroianni J; Zenz T; Andrlova H; Mathew NR; Claus R; Hutter B; Fröhling S; Brors B; Pfeifer D; Pantic M; Bartsch I; Spehl TS; Meyer PT; Duyster J; Zirlik K; Brummer T; Zeiser R
    J Clin Invest; 2014 Nov; 124(11):5074-84. PubMed ID: 25329694
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.
    Xia J; Jia P; Hutchinson KE; Dahlman KB; Johnson D; Sosman J; Pao W; Zhao Z
    Mol Cancer Ther; 2014 Jul; 13(7):1918-28. PubMed ID: 24755198
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Migration inhibition of mammary epithelial cells by syk is blocked in the presence of DDR1 receptors.
    Neuhaus B; Bühren S; Böck B; Alves F; Vogel WF; Kiefer F
    Cell Mol Life Sci; 2011 Nov; 68(22):3757-70. PubMed ID: 21499918
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The ITK-syk fusion oncogene induces a T-cell lymphoproliferative disease in mice mimicking human disease.
    Dierks C; Adrian F; Fisch P; Ma H; Maurer H; Herchenbach D; Forster CU; Sprissler C; Liu G; Rottmann S; Guo GR; Katja Z; Veelken H; Warmuth M
    Cancer Res; 2010 Aug; 70(15):6193-204. PubMed ID: 20670954
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.
    Bailet O; Fenouille N; Abbe P; Robert G; Rocchi S; Gonthier N; Denoyelle C; Ticchioni M; Ortonne JP; Ballotti R; Deckert M; Tartare-Deckert S
    Cancer Res; 2009 Apr; 69(7):2748-56. PubMed ID: 19293188
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells.
    Radhakrishnan S; Arneson LN; Upshaw JL; Howe CL; Felts SJ; Colonna M; Leibson PJ; Rodriguez M; Pease LR
    J Immunol; 2008 Dec; 181(11):7863-72. PubMed ID: 19017976
    [TBL] [Abstract] [Full Text] [Related]  


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