BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND XPC, XP3, 7508, ENSG00000154767, XPCC AND Treatment
22 results:

  • 1. Successful treatment of non-melanoma skin cancer in three patients with Xeroderma Pigmentosum by modified ALA-PDT.
    Zheng J; Liu W; Zhou Z; Cao Z; Zhao Z; Wang X; Li M; Zhang G
    Photodiagnosis Photodyn Ther; 2023 Sep; 43():103694. PubMed ID: 37422200
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Recurrent squamous cell carcinoma and a novel mutation in a patient with xeroderma pigmentosum: a case report.
    Şahin EA; Taşkıran EZ; Kiper PÖŞ; Aydın B; Utine E
    J Med Case Rep; 2022 Jul; 16(1):306. PubMed ID: 35902966
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Isoconazole and Clemizole Hydrochloride Partially Reverse the Xeroderma Pigmentosum C Phenotype.
    Kobaisi F; Sulpice E; Barette C; Fayyad N; Fauvarque MO; Badran B; Fayyad-Kazan M; Fayyad-Kazan H; Gidrol X; Rachidi W
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360928
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Molecular analysis directs the prognosis, management and treatment of patients with xeroderma pigmentosum.
    Lehmann AR; Fassihi H
    DNA Repair (Amst); 2020 Sep; 93():102907. PubMed ID: 33087273
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Sequential decitabine and carboplatin treatment increases the DNA repair protein xpc, increases apoptosis and decreases proliferation in melanoma.
    Budden T; van der Westhuizen A; Bowden NA
    BMC Cancer; 2018 Jan; 18(1):100. PubMed ID: 29373959
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Identification of four novel xpc mutations in two xeroderma pigmentosum complementation group C patients and functional study of xpc Q320X mutant.
    Gu Y; Chang X; Dai S; Song Q; Zhao H; Lei P
    Gene; 2017 Sep; 628():162-169. PubMed ID: 28669926
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inorganic arsenic inhibits the nucleotide excision repair pathway and reduces the expression of xpc.
    Holcomb N; Goswami M; Han SG; Scott T; D'Orazio J; Orren DK; Gairola CG; Mellon I
    DNA Repair (Amst); 2017 Apr; 52():70-80. PubMed ID: 28237621
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Clinical and molecular epidemiological study of xeroderma pigmentosum in China: A case series of 19 patients.
    Zhou EY; Wang H; Lin Z; Xu G; Ma Z; Zhao J; Feng C; Duo L; Yin J; Yang Y
    J Dermatol; 2017 Jan; 44(1):71-75. PubMed ID: 27607234
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Repair of UVB-induced DNA damage is reduced in melanoma due to low xpc and global genome repair.
    Budden T; Davey RJ; Vilain RE; Ashton KA; Braye SG; Beveridge NJ; Bowden NA
    Oncotarget; 2016 Sep; 7(38):60940-60953. PubMed ID: 27487145
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts.
    Guillermo-Lagae R; Deep G; Ting H; Agarwal C; Agarwal R
    Oncotarget; 2015 Nov; 6(37):39594-606. PubMed ID: 26447614
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Readthrough of stop codons by use of aminoglycosides in cells from xeroderma pigmentosum group C patients.
    Kuschal C; Khan SG; Enk B; DiGiovanna JJ; Kraemer KH
    Exp Dermatol; 2015 Apr; 24(4):296-7. PubMed ID: 25651777
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.
    Dupuy A; Valton J; Leduc S; Armier J; Galetto R; Gouble A; Lebuhotel C; Stary A; Pâques F; Duchateau P; Sarasin A; Daboussi F
    PLoS One; 2013; 8(11):e78678. PubMed ID: 24236034
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Repair of UV photolesions in xeroderma pigmentosum group C cells induced by translational readthrough of premature termination codons.
    Kuschal C; DiGiovanna JJ; Khan SG; Gatti RA; Kraemer KH
    Proc Natl Acad Sci U S A; 2013 Nov; 110(48):19483-8. PubMed ID: 24218596
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Disorders of nucleotide excision repair.
    Rapin I
    Handb Clin Neurol; 2013; 113():1637-50. PubMed ID: 23622385
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/xpc-mediated DNA repair.
    Barckhausen C; Roos WP; Naumann SC; Kaina B
    Oncogene; 2014 Apr; 33(15):1964-74. PubMed ID: 23604128
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Role of AMPK in UVB-induced DNA damage repair and growth control.
    Wu CL; Qiang L; Han W; Ming M; Viollet B; He YY
    Oncogene; 2013 May; 32(21):2682-9. PubMed ID: 22751115
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Preclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells.
    Warrick E; Garcia M; Chagnoleau C; Chevallier O; Bergoglio V; Sartori D; Mavilio F; Angulo JF; Avril MF; Sarasin A; Larcher F; Del Rio M; Bernerd F; Magnaldo T
    Mol Ther; 2012 Apr; 20(4):798-807. PubMed ID: 22068429
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition.
    Kuschal C; Thoms KM; Boeckmann L; Laspe P; Apel A; Schön MP; Emmert S
    Exp Dermatol; 2011 Oct; 20(10):795-9. PubMed ID: 21707758
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. xpc silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species.
    Rezvani HR; Rossignol R; Ali N; Benard G; Tang X; Yang HS; Jouary T; de Verneuil H; Taïeb A; Kim AL; Mazurier F
    Biochim Biophys Acta; 2011 Jun; 1807(6):609-19. PubMed ID: 21167810
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Psoralen-induced DNA interstrand cross-links block transcription and induce p53 in an ataxia-telangiectasia and rad3-related-dependent manner.
    Derheimer FA; Hicks JK; Paulsen MT; Canman CE; Ljungman M
    Mol Pharmacol; 2009 Mar; 75(3):599-607. PubMed ID: 19064630
    [TBL] [Abstract] [Full Text] [Related]  


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