BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Skin cancer AND uPA AND Treatment
20 results:

  • 1. upaR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and upaR overexpression and rise of ERK1,2 signaling in endothelial cells.
    Biagioni A; Laurenzana A; Menicacci B; Peppicelli S; Andreucci E; Bianchini F; Guasti D; Paoli P; Serratì S; Mocali A; Calorini L; Del Rosso M; Fibbi G; Chillà A; Margheri F
    Cell Mol Life Sci; 2021 Mar; 78(6):3057-3072. PubMed ID: 33237352
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Chrysin inhibit human melanoma A375.S2 cell migration and invasion via affecting MAPK signaling and NF-κB signaling pathway in vitro.
    Chen HY; Jiang YW; Kuo CL; Way TD; Chou YC; Chang YS; Chung JG
    Environ Toxicol; 2019 Apr; 34(4):434-442. PubMed ID: 30578657
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, upa, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro.
    Liu JF; Lai KC; Peng SF; Maraming P; Huang YP; Huang AC; Chueh FS; Huang WW; Chung JG
    Molecules; 2018 Aug; 23(8):. PubMed ID: 30104528
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cold atmospheric plasma (CAP) activates angiogenesis-related molecules in skin keratinocytes, fibroblasts and endothelial cells and improves wound angiogenesis in an autocrine and paracrine mode.
    Arndt S; Unger P; Berneburg M; Bosserhoff AK; Karrer S
    J Dermatol Sci; 2018 Feb; 89(2):181-190. PubMed ID: 29191392
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Chronic Resveratrol treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.
    Menicacci B; Laurenzana A; Chillà A; Margheri F; Peppicelli S; Tanganelli E; Fibbi G; Giovannelli L; Del Rosso M; Mocali A
    J Gerontol A Biol Sci Med Sci; 2017 Sep; 72(9):1187-1195. PubMed ID: 28329136
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. The receptor for urokinase-plasminogen activator (upaR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.
    Margheri F; Luciani C; Taddei ML; Giannoni E; Laurenzana A; Biagioni A; Chillà A; Chiarugi P; Fibbi G; Del Rosso M
    Oncotarget; 2014 Mar; 5(6):1538-53. PubMed ID: 24681666
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Holothurian glycosaminoglycan inhibits metastasis and thrombosis via targeting of nuclear factor-κB/tissue factor/Factor Xa pathway in melanoma B16F10 cells.
    Zhao Y; Zhang D; Wang S; Tao L; Wang A; Chen W; Zhu Z; Zheng S; Gao X; Lu Y
    PLoS One; 2013; 8(2):e56557. PubMed ID: 23437168
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Selective photodetection and photodynamic therapy for prostate cancer through targeting of proteolytic activity.
    Zuluaga MF; Sekkat N; Gabriel D; van den Bergh H; Lange N
    Mol Cancer Ther; 2013 Mar; 12(3):306-13. PubMed ID: 23270928
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity.
    Jiang J; Eliaz I; Sliva D
    Int J Oncol; 2011 Jun; 38(6):1675-82. PubMed ID: 21468543
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Suppression of upa and upaR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.
    Raghu H; Lakka SS; Gondi CS; Mohanam S; Dinh DH; Gujrati M; Rao JS
    PLoS One; 2010 Aug; 5(8):e12458. PubMed ID: 20805979
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The upa receptor and the somatomedin B region of vitronectin direct the localization of upa to focal adhesions in microvessel endothelial cells.
    Salasznyk RM; Zappala M; Zheng M; Yu L; Wilkins-Port C; McKeown-Longo PJ
    Matrix Biol; 2007 Jun; 26(5):359-70. PubMed ID: 17344041
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. U0126, a mitogen-activated protein kinase kinase inhibitor, inhibits the invasion of human A375 melanoma cells.
    Ge X; Fu YM; Meadows GG
    Cancer Lett; 2002 May; 179(2):133-40. PubMed ID: 11888667
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Antibodies to PAI-1 alter the invasive and migratory properties of human tumour cells in vitro.
    Brooks TD; Slomp J; Quax PH; De Bart AC; Spencer MT; Verheijen JH; Charlton PA
    Clin Exp Metastasis; 2000; 18(6):445-53. PubMed ID: 11592301
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor alphaVbeta3.
    Khatib AM; Nip J; Fallavollita L; Lehmann M; Jensen G; Brodt P
    Int J Cancer; 2001 Feb; 91(3):300-8. PubMed ID: 11169951
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. High tPA-expression in primary melanoma of the limb correlates with good prognosis.
    Ferrier CM; Suciu S; van Geloof WL; Straatman H; Eggermont AM; Koops HS; Kroon BB; Lejeune FJ; Kleeberg UR; van Muijen GN; Ruiter DJ
    Br J Cancer; 2000 Nov; 83(10):1351-9. PubMed ID: 11044361
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Effect of hyperthermia on the viability and the fibrinolytic potential of human cancer cell lines.
    Fukao H; Ikeda M; Ichikawa T; Inufusa H; Okada K; Ueshima S; Matsuo O
    Clin Chim Acta; 2000 Jun; 296(1-2):17-33. PubMed ID: 10807968
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Effect of retinoic acid on plasminogen activator expression in human melanoma cells.
    Alexander CL; Edward M; MacKie RM
    Melanoma Res; 1999 Aug; 9(4):360-7. PubMed ID: 10504054
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Receptor-mediated endocytosis of urokinase-type plasminogen activator is regulated by cAMP-dependent protein kinase.
    Goretzki L; Mueller BM
    J Cell Sci; 1997 Jun; 110 ( Pt 12)():1395-402. PubMed ID: 9217325
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Melanocyte mediated paracrine induction of extracellular matrix degrading proteases in squamous cell carcinoma cells.
    Borchers AH; Sanders LA; Powell MB; Bowden GT
    Exp Cell Res; 1997 Feb; 231(1):61-5. PubMed ID: 9056412
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae.
    Stahl A; Mueller BM
    J Cell Biol; 1995 Apr; 129(2):335-44. PubMed ID: 7721938
    [TBL] [Abstract] [Full Text] [Related]  


    of 1.