Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Small Cell Lung Cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207
3156 results:

  • 1. Exosome miR-101-3p derived from bone marrow mesenchymal stem cells promotes radiotherapy sensitivity in non-small cell lung cancer by regulating DNA damage repair and autophagy levels through EZH2.
    Sun H; Zhu R; Guo X; Zhao P; Zhang R; Zhao Z; Zhou H
    Pathol Res Pract; 2024 Apr; 256():155271. PubMed ID: 38574630
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/akt pathway.
    Yang F; Zheng Y; Luo Q; Zhang S; Yang S; Chen X
    BMC Cancer; 2024 Apr; 24(1):408. PubMed ID: 38566039
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Predictive value of immediate early response 5 like (IER5L) in the prognosis and immune checkpoint blockade therapy of non-small cell lung cancer patients.
    Wang N; Tan X; Cao S; Liu M
    Pathol Res Pract; 2024 Apr; 256():155270. PubMed ID: 38552564
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Suppression of NSCLC progression via the co-administration of Danusertib, an AURK inhibitor, and KRIBB11, an HSF1 inhibitor.
    Zhang X; Lei Y; Chen X; He J; Liu Z; Zhu W; Xu Y; Jin X
    Biochem Pharmacol; 2024 May; 223():116155. PubMed ID: 38521474
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Discovery of Novel 5,6-Dihydro-4
    Yang L; Li Y; Du Y; Guo Y; Guo Z; Liu B; Liu J; Liu Y; Niu H; Sun Y; Yan H; Yang Y; Yu S; Zhang Y; Zhang Y; Zheng K; Zheng N; Zhang X; Zhang Q; Hu L
    J Med Chem; 2024 Apr; 67(7):5662-5682. PubMed ID: 38518121
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by akt inhibition.
    Deben C; Boullosa LF; Fortes FR; De La Hoz EC; Le Compte M; Seghers S; Peeters M; Vanlanduit S; Lin A; Dijkstra KK; Van Schil P; Hendriks JMH; Prenen H; Roeyen G; Lardon F; Smits E
    J Exp Clin Cancer Res; 2024 Mar; 43(1):88. PubMed ID: 38515178
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. [Demethylzeylasteral inhibits proliferation, migration and invasion and promotes apoptosis of non-small cell lung cancer cells by inhibiting the akt/CREB signaling pathway].
    Han Q; Ye M; Jin Q
    Nan Fang Yi Ke Da Xue Xue Bao; 2024 Feb; 44(2):280-288. PubMed ID: 38501413
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer.
    Han F; Chen S; Zhang K; Zhang K; Wang M; Wang P
    J Transl Med; 2024 Mar; 22(1):288. PubMed ID: 38493128
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via akt/FoxO3a/Puma axis.
    Shanshan W; Hongying M; Jingjing F; Rui Y
    Toxicol In Vitro; 2024 May; 97():105801. PubMed ID: 38479708
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Anlotinib Inhibits Cisplatin Resistance in Non-small-cell lung cancer cells by Inhibiting MCL-1 Expression via MET/STAT3/akt Pathway.
    Wang L; Xu L; Han S; Zhu X
    Can Respir J; 2024; 2024():2632014. PubMed ID: 38468814
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Corynoxine triggers cell death via activating PP2A and regulating akt-mTOR/GSK3β axes in NSCLC.
    Hou G; Hu W; Sang Y; Gan X; Xu H; Hu Q; Cao X
    Biochem Pharmacol; 2024 Apr; 222():116110. PubMed ID: 38460908
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. PIK3CA mutation as an acquired resistance driver to EGFR-TKIs in non-small cell lung cancer: Clinical challenges and opportunities.
    Liu X; Mei W; Zhang P; Zeng C
    Pharmacol Res; 2024 Apr; 202():107123. PubMed ID: 38432445
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Synergistic anti-tumor effects of lenalidomide and gefitinib by upregulating ADRB2 and inactivating the mTOR/PI3K/akt signaling pathway in lung adenocarcinoma.
    Zhou S; Deng M; Bian X; Shi J; Liang R; Tao M
    Cell Mol Biol (Noisy-le-grand); 2024 Feb; 70(2):120-127. PubMed ID: 38430032
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Exploration of Ginkgo biloba leaves on non-small cell lung cancer based on network pharmacology and molecular docking.
    Wang M; Li R; Bai M; Zhou X
    Medicine (Baltimore); 2024 Mar; 103(9):e37218. PubMed ID: 38428907
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Modulation of cellular metabolism and alleviation of bacterial dysbiosis by Aconiti Lateralis Radix Praeparata in non-small cell lung cancer treatment.
    Zhang W; Ding M; Feng Y; Cai S; Luo Z; Shan J; Di L
    Phytomedicine; 2024 Apr; 126():155099. PubMed ID: 38412665
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. [Mechanism of n-butanol fraction of Wenxia Formula combining with gefitinib in treating non-small cell lung cancer based on network pharmacology and in vitro experiment].
    Chen RJ; Bi QY; Shi JM; Zhong J; Han JT; Ji XM
    Zhongguo Zhong Yao Za Zhi; 2024 Jan; 49(2):471-486. PubMed ID: 38403323
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Discriminative and prognostic significance of LINC00623 for lung adenocarcinoma.
    Lin Y; Dong C; Zhang J; Zhu Y
    Ann Biol Clin (Paris); 2024 Feb; 81(6):591-601. PubMed ID: 38391164
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy.
    Raskova Kafkova L; Mierzwicka JM; Chakraborty P; Jakubec P; Fischer O; Skarda J; Maly P; Raska M
    Front Immunol; 2024; 15():1342086. PubMed ID: 38384472
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. G protein-coupled estrogen receptor activates PI3K/akt/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis.
    Chen J; Zhao R; Wang Y; Xiao H; Lin W; Diao M; He S; Mei P; Liao Y
    Mol Med; 2024 Feb; 30(1):28. PubMed ID: 38383297
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. small Molecule SHP2 Inhibitor LXQ-217 Affects lung cancer cell Proliferation in Vitro and in Vivo.
    Sun H; Bai X; Zhang Y; Gao Y; Dai J; Xing P; Zhu J; Liu R; Wang Z; Li X
    Chem Biodivers; 2024 Apr; 21(4):e202301610. PubMed ID: 38379194
    [TBL] [Abstract] [Full Text] [Related]  


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