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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Small Cell Lung Cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207
3195 results:

  • 1. ENDOlung trial. A phase 1/2 study of the akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer.
    Leary A; Estévez-García P; Sabatier R; Ray-Coquard I; Romeo M; Barretina-Ginesta P; Gil-Martin M; Garralda E; Bosch-Barrera J; Morán T; Martin-Martorell P; Nadal E; Gascón P; Rodon J; Lizcano JM; Muñoz-Guardiola P; Fierro-Durán G; Pedrós-Gámez O; Pérez-Montoyo H; Yeste-Velasco M; Cortal M; Pérez-Campos A; Alfon J; Domenech C; Pérez-Fidalgo A; Oaknin A
    BMC Cancer; 2024 Jul; 24(1):876. PubMed ID: 39039449
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Hypoxia-enhanced YAP1-EIF4A3 interaction drives circ_0007386 circularization by competing with CRIM1 pre-mRNA linear splicing and promotes non-small cell lung cancer progression.
    Li L; Liu D; Chen T; Wei C; Qiao Y; Liu W; Liang Y; Liang Z; Chen C; Li D; Wu B; Zhao X; Huang D; Wu D
    J Exp Clin Cancer Res; 2024 Jul; 43(1):200. PubMed ID: 39030638
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. [Solasonine promotes apoptosis of non-small cell lung cancer cells by regulating the Bcl-2/Bax/caspase-3 pathway].
    Chen G; Liao X; Sun P; Cen H; Shu S; Li B; Li J
    Nan Fang Yi Ke Da Xue Xue Bao; 2024 Jun; 44(6):1109-1116. PubMed ID: 38977340
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/akt pathway.
    He L; Chen H; Ruan B; He L; Luo M; Fu Y; Zou R
    J Cancer Res Clin Oncol; 2024 Jul; 150(7):335. PubMed ID: 38969831
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integration of Electrospun Scaffolds and Biological Polymers for Enhancing the Delivery and Efficacy of Mesenchymal Stem/Stromal cell Therapies.
    Barcena AJR; Mishra A; Bolinas DKM; Martin BM; Melancon MP
    Front Biosci (Landmark Ed); 2024 Jun; 29(6):228. PubMed ID: 38940050
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. 5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/akt inhibition by in vitro and in silico approaches.
    Ginovyan M; Javrushyan H; Hovhannisyan S; Nadiryan E; Sevoyan G; Harutyunyan T; Gevorgyan S; Karabekian Z; Maloyan A; Avtandilyan N
    Sci Rep; 2024 Jun; 14(1):14676. PubMed ID: 38918540
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Antibody nanoparticle conjugate-based targeted immunotherapy for non-small cell lung cancer.
    Saha T; Fojtů M; Nagar AV; Thurakkal L; Srinivasan BB; Mukherjee M; Sibiyon A; Aggarwal H; Samuel A; Dash C; Jang HL; Sengupta S
    Sci Adv; 2024 Jun; 10(24):eadi2046. PubMed ID: 38875335
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Iridium(III) carbene complexes as potent girdin inhibitors against metastatic cancers.
    Ruan ML; Ni WX; Chu JCH; Lam TL; Law KC; Zhang Y; Yang G; He Y; Zhang C; Fung YME; Liu T; Huang T; Lok CN; Chan SL; Che CM
    Proc Natl Acad Sci U S A; 2024 Jun; 121(25):e2316615121. PubMed ID: 38861602
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Evaluating the Clinical Characteristics and Prognosis of Advanced Non-small cell lung cancer with Exon 20 Insertions.
    Wang H; Xu Y; Lin J; Huang Y
    Cancer Control; 2024; 31():10732748241262190. PubMed ID: 38857163
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. PCK2 induces gefitinib resistance by suppresses ferroptosis in non-small cell lung cancer.
    Yan T; Zhang N; Liu F; Wang H; Zhang J; Jin X; Jiang S
    Biochem Biophys Res Commun; 2024 Sep; 723():150200. PubMed ID: 38850814
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Juglone triggers apoptosis of non-small cell lung cancer through the reactive oxygen species -mediated PI3K/akt pathway.
    Zhong J; Hua Y; Zou S; Wang B
    PLoS One; 2024; 19(5):e0299921. PubMed ID: 38814975
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Non-small cell lung carcinoma with clear cell features: a clinicopathologic, immunohistochemical, and molecular study of 31 cases.
    Suster DI; Ronen N; Mejbel HA; Harada S; Mackinnon AC; Suster S
    Virchows Arch; 2024 Jul; 485(1):83-96. PubMed ID: 38814477
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.
    Bhusare N; Yadav T; Nandave M; Gadade A; Dighe V; Peters GJ; Kumar MS; Yergeri MC
    Drug Dev Res; 2024 Jun; 85(4):e22212. PubMed ID: 38798193
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP.
    Wu W; Li J; Yin Y; Zhou Y; Huang X; Cao Y; Chen X; Zhou Y; Du J; Xu Z; Yang B; He Q; Yang X; Hu Y; Yan H; Luo P
    Cell Biol Toxicol; 2024 May; 40(1):38. PubMed ID: 38789868
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. [Role of COX-2/PGE2/EP4 Axis-induced Macrophage Functional Activation 
in NSCLC Development].
    Zhao J; Zhu Q; Zhang Y; Li G; Zhang Y; Li F; Bian L
    Zhongguo Fei Ai Za Zhi; 2024 Apr; 27(4):245-256. PubMed ID: 38769827
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Combination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR signaling pathway.
    Wang H; Du X; Liu W; Zhang C; Li Y; Hou J; Yu Y; Li G; Wang Q
    Respir Res; 2024 May; 25(1):215. PubMed ID: 38764025
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Identifying the Multitarget Pharmacological Mechanism of Action of Genistein on lung cancer by Integrating Network Pharmacology and Molecular Dynamic Simulation.
    Das R; Woo J
    Molecules; 2024 Apr; 29(9):. PubMed ID: 38731403
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the PI3K/akt signaling pathway.
    Ai Y; Wan C; Chen Z; Wang Y; Zhao W; Huang W
    J Biosci; 2024; 49():. PubMed ID: 38726826
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. circ_PPAPDC1A promotes Osimertinib resistance by sponging the miR-30a-3p/ IGF1R pathway in non-small cell lung cancer (NSCLC).
    Tang YF; Liu ZH; Zhang LY; Shi SH; Xu S; Ma JA; Hu CH; Zou FW
    Mol Cancer; 2024 May; 23(1):91. PubMed ID: 38715012
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.
    Xuan YF; Lu S; Ou YJ; Bao XB; Huan XJ; Song SS; Miao ZH; Wang YQ
    Biochem Biophys Res Commun; 2024 Jul; 716():150011. PubMed ID: 38704890
    [TBL] [Abstract] [Full Text] [Related]  


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