Terms: = Small Cell Lung Cancer AND AKT1, P31749, RAC-ALPHA, RAC, PRKBA, PKB-ALPHA, PKB, MGC99656, AKT, ENSG00000142208, 207 AND Treatment
1551 results:
1. ENDOlung trial. A phase 1/2 study of the akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer.
Leary A; Estévez-García P; Sabatier R; Ray-Coquard I; Romeo M; Barretina-Ginesta P; Gil-Martin M; Garralda E; Bosch-Barrera J; Morán T; Martin-Martorell P; Nadal E; Gascón P; Rodon J; Lizcano JM; Muñoz-Guardiola P; Fierro-Durán G; Pedrós-Gámez O; Pérez-Montoyo H; Yeste-Velasco M; Cortal M; Pérez-Campos A; Alfon J; Domenech C; Pérez-Fidalgo A; Oaknin A
BMC Cancer; 2024 Jul; 24(1):876. PubMed ID: 39039449
[TBL] [Abstract] [Full Text] [Related]
2. Hypoxia-enhanced YAP1-EIF4A3 interaction drives circ_0007386 circularization by competing with CRIM1 pre-mRNA linear splicing and promotes non-small cell lung cancer progression.
Li L; Liu D; Chen T; Wei C; Qiao Y; Liu W; Liang Y; Liang Z; Chen C; Li D; Wu B; Zhao X; Huang D; Wu D
J Exp Clin Cancer Res; 2024 Jul; 43(1):200. PubMed ID: 39030638
[TBL] [Abstract] [Full Text] [Related]
3. [Solasonine promotes apoptosis of non-small cell lung cancer cells by regulating the Bcl-2/Bax/caspase-3 pathway].
Chen G; Liao X; Sun P; Cen H; Shu S; Li B; Li J
Nan Fang Yi Ke Da Xue Xue Bao; 2024 Jun; 44(6):1109-1116. PubMed ID: 38977340
[TBL] [Abstract] [Full Text] [Related]
4. Integration of Electrospun Scaffolds and Biological Polymers for Enhancing the Delivery and Efficacy of Mesenchymal Stem/Stromal cell Therapies.
Barcena AJR; Mishra A; Bolinas DKM; Martin BM; Melancon MP
Front Biosci (Landmark Ed); 2024 Jun; 29(6):228. PubMed ID: 38940050
[TBL] [Abstract] [Full Text] [Related]
5. 5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/akt inhibition by in vitro and in silico approaches.
Ginovyan M; Javrushyan H; Hovhannisyan S; Nadiryan E; Sevoyan G; Harutyunyan T; Gevorgyan S; Karabekian Z; Maloyan A; Avtandilyan N
Sci Rep; 2024 Jun; 14(1):14676. PubMed ID: 38918540
[TBL] [Abstract] [Full Text] [Related]
6. Antibody nanoparticle conjugate-based targeted immunotherapy for non-small cell lung cancer.
Saha T; Fojtů M; Nagar AV; Thurakkal L; Srinivasan BB; Mukherjee M; Sibiyon A; Aggarwal H; Samuel A; Dash C; Jang HL; Sengupta S
Sci Adv; 2024 Jun; 10(24):eadi2046. PubMed ID: 38875335
[TBL] [Abstract] [Full Text] [Related]
7. Evaluating the Clinical Characteristics and Prognosis of Advanced Non-small cell lung cancer with Exon 20 Insertions.
Wang H; Xu Y; Lin J; Huang Y
Cancer Control; 2024; 31():10732748241262190. PubMed ID: 38857163
[TBL] [Abstract] [Full Text] [Related]
8. PCK2 induces gefitinib resistance by suppresses ferroptosis in non-small cell lung cancer.
Yan T; Zhang N; Liu F; Wang H; Zhang J; Jin X; Jiang S
Biochem Biophys Res Commun; 2024 Sep; 723():150200. PubMed ID: 38850814
[TBL] [Abstract] [Full Text] [Related]
9. Juglone triggers apoptosis of non-small cell lung cancer through the reactive oxygen species -mediated PI3K/akt pathway.
Zhong J; Hua Y; Zou S; Wang B
PLoS One; 2024; 19(5):e0299921. PubMed ID: 38814975
[TBL] [Abstract] [Full Text] [Related]
10. Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.
Bhusare N; Yadav T; Nandave M; Gadade A; Dighe V; Peters GJ; Kumar MS; Yergeri MC
Drug Dev Res; 2024 Jun; 85(4):e22212. PubMed ID: 38798193
[TBL] [Abstract] [Full Text] [Related]
11. Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP.
Wu W; Li J; Yin Y; Zhou Y; Huang X; Cao Y; Chen X; Zhou Y; Du J; Xu Z; Yang B; He Q; Yang X; Hu Y; Yan H; Luo P
Cell Biol Toxicol; 2024 May; 40(1):38. PubMed ID: 38789868
[TBL] [Abstract] [Full Text] [Related]
12. Combination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR signaling pathway.
Wang H; Du X; Liu W; Zhang C; Li Y; Hou J; Yu Y; Li G; Wang Q
Respir Res; 2024 May; 25(1):215. PubMed ID: 38764025
[TBL] [Abstract] [Full Text] [Related]
13. Identifying the Multitarget Pharmacological Mechanism of Action of Genistein on lung cancer by Integrating Network Pharmacology and Molecular Dynamic Simulation.
Das R; Woo J
Molecules; 2024 Apr; 29(9):. PubMed ID: 38731403
[TBL] [Abstract] [Full Text] [Related]
14. SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the PI3K/akt signaling pathway.
Ai Y; Wan C; Chen Z; Wang Y; Zhao W; Huang W
J Biosci; 2024; 49():. PubMed ID: 38726826
[TBL] [Abstract] [Full Text] [Related]
15. The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.
Xuan YF; Lu S; Ou YJ; Bao XB; Huan XJ; Song SS; Miao ZH; Wang YQ
Biochem Biophys Res Commun; 2024 Jul; 716():150011. PubMed ID: 38704890
[TBL] [Abstract] [Full Text] [Related]
16. The potential role of circular RNAs -regulated PI3K signaling in non-small cell lung cancer: Molecular insights and clinical perspective.
Kahkesh S; Khoshnazar SM; Gholinezhad Y; Esmailzadeh S; Hosseini SA; Alimohammadi M; Mafi A
Pathol Res Pract; 2024 May; 257():155316. PubMed ID: 38692125
[TBL] [Abstract] [Full Text] [Related]
17. CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via PI3K/akt Signaling Pathway.
Wei N; Wu X; Yu Y; Zhou H; Cui K; Zhao X; Zhang X
Front Biosci (Landmark Ed); 2024 Apr; 29(4):140. PubMed ID: 38682195
[TBL] [Abstract] [Full Text] [Related]
18. Elucidating the mechanism of action of Isobavachalcone induced autophagy and apoptosis in non-small cell lung cancer by network pharmacology and experimental validation methods.
Wang L; Wang Z; Ni Y; Wang X; Zhang T; Hu M; Lian C; Wang X; Zhang J
Gene; 2024 Aug; 918():148474. PubMed ID: 38670393
[TBL] [Abstract] [Full Text] [Related]
19. Targeted inhibition of the PI3K/akt/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer.
Li XQ; Cheng XJ; Wu J; Wu KF; Liu T
Cell Mol Biol Lett; 2024 Apr; 29(1):58. PubMed ID: 38649803
[TBL] [Abstract] [Full Text] [Related]
20. Anlotinib may enhance the efficacy of anti-PD1 therapy by inhibiting the akt pathway and promoting the apoptosis of CAFs in lung adenocarcinoma.
Tang H; You T; Ge H; Gao J; Wang Y; Bai C; Sun Z; Han Q; Zhao RC
Int Immunopharmacol; 2024 May; 133():112053. PubMed ID: 38615380
[TBL] [Abstract] [Full Text] [Related]
[Next]
