Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Small Cell Lung Cancer AND TP53, TRP53, 7157, ENSG00000141510, P04637, LFS1, P53 AND Clinical Outcome
62 results:

  • 1. Co-Occurring Alterations in Multiple Tumor Suppressor Genes Are Associated With Worse outcomes in Patients With EGFR-Mutant lung cancer.
    Stockhammer P; Grant M; Wurtz A; Foggetti G; Expósito F; Gu J; Zhao H; Choi J; Chung S; Li F; Walther Z; Dietz J; Duffield E; Gettinger S; Politi K; Goldberg SB
    J Thorac Oncol; 2024 Feb; 19(2):240-251. PubMed ID: 37806385
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. RELAY, Ramucirumab Plus Erlotinib (RAM+ERL) in Untreated Metastatic EGFR-Mutant NSCLC (EGFR+ NSCLC): Association Between tp53 Status and clinical outcome.
    Nishio M; Paz-Ares L; Reck M; Nakagawa K; Garon EB; Popat S; Ceccarelli M; Graham HT; Visseren-Grul C; Novello S
    Clin Lung Cancer; 2023 Jul; 24(5):415-428. PubMed ID: 37076395
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The evolution of lung cancer and impact of subclonal selection in TRACERx.
    Frankell AM; Dietzen M; Al Bakir M; Lim EL; Karasaki T; Ward S; Veeriah S; Colliver E; Huebner A; Bunkum A; Hill MS; Grigoriadis K; Moore DA; Black JRM; Liu WK; Thol K; Pich O; Watkins TBK; Naceur-Lombardelli C; Cook DE; Salgado R; Wilson GA; Bailey C; Angelova M; Bentham R; Martínez-Ruiz C; Abbosh C; Nicholson AG; Le Quesne J; Biswas D; Rosenthal R; Puttick C; Hessey S; Lee C; Prymas P; Toncheva A; Smith J; Xing W; Nicod J; Price G; Kerr KM; Naidu B; Middleton G; Blyth KG; Fennell DA; Forster MD; Lee SM; Falzon M; Hewish M; Shackcloth MJ; Lim E; Benafif S; Russell P; Boleti E; Krebs MG; Lester JF; Papadatos-Pastos D; Ahmad T; Thakrar RM; Lawrence D; Navani N; Janes SM; Dive C; Blackhall FH; Summers Y; Cave J; Marafioti T; Herrero J; Quezada SA; Peggs KS; Schwarz RF; Van Loo P; Miedema DM; Birkbak NJ; Hiley CT; Hackshaw A; Zaccaria S; ; Jamal-Hanjani M; McGranahan N; Swanton C
    Nature; 2023 Apr; 616(7957):525-533. PubMed ID: 37046096
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Genomic Characteristics and the Potential clinical Implications in Oligometastatic Non-small cell lung cancer.
    Liao R; Chen K; Li J; He H; Yi G; Huang M; Chen R; Shen L; Zhang X; Xu Z; Yang Z; Peng Y
    Cancer Res Treat; 2023 Jul; 55(3):814-831. PubMed ID: 36634615
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The development of a tumor-associated autoantibodies panel to predict clinical outcomes for immune checkpoint inhibitor-based treatment in patients with advanced non-small-cell lung cancer.
    Zhao J; Wu Y; Yue Y; Chen M; Xu Y; Liu X; Liu X; Gao X; Wang H; Si X; Zhong W; Zhang X; Zhang L; Wang M
    Thorac Cancer; 2023 Feb; 14(5):497-505. PubMed ID: 36594104
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Evaluate the Prognosis of
    Cao J; J Gu J; Liang Y; Wang B
    Technol Cancer Res Treat; 2022; 21():15330338221138213. PubMed ID: 36524293
    [No Abstract]    [Full Text] [Related]  

  • 7. Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine lung cancer (nNGM).
    Janning M; Süptitz J; Albers-Leischner C; Delpy P; Tufman A; Velthaus-Rusik JL; Reck M; Jung A; Kauffmann-Guerrero D; Bonzheim I; Brändlein S; Hummel HD; Wiesweg M; Schildhaus HU; Stratmann JA; Sebastian M; Alt J; Buth J; Esposito I; Berger J; Tögel L; Saalfeld FC; Wermke M; Merkelbach-Bruse S; Hillmer AM; Klauschen F; Bokemeyer C; Buettner R; Wolf J; Loges S;
    Ann Oncol; 2022 Jun; 33(6):602-615. PubMed ID: 35263633
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. EphB4 as a Novel Target for the EGFR-Independent Suppressive Effects of Osimertinib on cell Cycle Progression in Non-small cell lung cancer.
    Nanamiya R; Saito-Koyama R; Miki Y; Inoue C; Asavasupreechar T; Abe J; Sato I; Sasano H
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445227
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The Effect of GLUT1 on the Survival Rate and Immune cell Infiltration of lung Adenocarcinoma and Squamous cell Carcinoma: A Meta and Bioinformatics Analysis.
    Zhang G; Dong R; Kong D; Liu B; Zha Y; Luo M
    Anticancer Agents Med Chem; 2022; 22(2):223-238. PubMed ID: 34238200
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-small cell lung cancer and IMR90 lung Fibroblast cell Lines.
    Monroe JD; Moolani SA; Irihamye EN; Speed JS; Gibert Y; Smith ME
    Cells; 2020 Dec; 9(12):. PubMed ID: 33302475
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Acquired resistance to osimertinib in patients with non-small-cell lung cancer: mechanisms and clinical outcomes.
    Mu Y; Hao X; Xing P; Hu X; Wang Y; Li T; Zhang J; Xu Z; Li J
    J Cancer Res Clin Oncol; 2020 Sep; 146(9):2427-2433. PubMed ID: 32385709
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Analysis of the Genomic Landscape in ALK+ NSCLC Patients Identifies Novel Aberrations Associated with clinical outcomes.
    Couëtoux du Tertre M; Marques M; Tremblay L; Bouchard N; Diaconescu R; Blais N; Couture C; Pelsser V; Wang H; Higenell V; Izzi L; Gambaro K; Hoffert C; Srivastava A; Spatz A; Rousseau C; McNamara S; Cohen V; Batist G; Agulnik J
    Mol Cancer Ther; 2019 Sep; 18(9):1628-1636. PubMed ID: 31243098
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Concurrent Genetic Alterations Predict the Progression to Target Therapy in EGFR-Mutated Advanced NSCLC.
    Kim Y; Lee B; Shim JH; Lee SH; Park WY; Choi YL; Sun JM; Ahn JS; Ahn MJ; Park K
    J Thorac Oncol; 2019 Feb; 14(2):193-202. PubMed ID: 30391576
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Usefulness of complementary next-generation sequencing and quantitative immunohistochemistry panels for predicting brain metastases and selecting treatment outcomes of non-small cell lung cancer.
    Machado-Rugolo J; Fabro AT; Ascheri D; Farhat C; Ab'Saber AM; de Sá VK; Nagai MA; Takagaki T; Terra R; Parra ER; Capelozzi VL
    Hum Pathol; 2019 Jan; 83():177-191. PubMed ID: 30218756
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. ERβ Sensitizes NSCLC to Chemotherapy by Regulating DNA Damage Response.
    Nikolos F; Thomas C; Bado I; Gustafsson JÅ
    Mol Cancer Res; 2018 Feb; 16(2):233-242. PubMed ID: 29117942
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. p53 gain-of-function mutations increase Cdc7-dependent replication initiation.
    Datta A; Ghatak D; Das S; Banerjee T; Paul A; Butti R; Gorain M; Ghuwalewala S; Roychowdhury A; Alam SK; Das P; Chatterjee R; Dasgupta M; Panda CK; Kundu GC; Roychoudhury S
    EMBO Rep; 2017 Nov; 18(11):2030-2050. PubMed ID: 28887320
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Tracking the Evolution of Non-small-cell lung cancer.
    Jamal-Hanjani M; Wilson GA; McGranahan N; Birkbak NJ; Watkins TBK; Veeriah S; Shafi S; Johnson DH; Mitter R; Rosenthal R; Salm M; Horswell S; Escudero M; Matthews N; Rowan A; Chambers T; Moore DA; Turajlic S; Xu H; Lee SM; Forster MD; Ahmad T; Hiley CT; Abbosh C; Falzon M; Borg E; Marafioti T; Lawrence D; Hayward M; Kolvekar S; Panagiotopoulos N; Janes SM; Thakrar R; Ahmed A; Blackhall F; Summers Y; Shah R; Joseph L; Quinn AM; Crosbie PA; Naidu B; Middleton G; Langman G; Trotter S; Nicolson M; Remmen H; Kerr K; Chetty M; Gomersall L; Fennell DA; Nakas A; Rathinam S; Anand G; Khan S; Russell P; Ezhil V; Ismail B; Irvin-Sellers M; Prakash V; Lester JF; Kornaszewska M; Attanoos R; Adams H; Davies H; Dentro S; Taniere P; O'Sullivan B; Lowe HL; Hartley JA; Iles N; Bell H; Ngai Y; Shaw JA; Herrero J; Szallasi Z; Schwarz RF; Stewart A; Quezada SA; Le Quesne J; Van Loo P; Dive C; Hackshaw A; Swanton C;
    N Engl J Med; 2017 Jun; 376(22):2109-2121. PubMed ID: 28445112
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Xenobiotic/drug metabolizing enzyme and tp53 polymorphisms and clinical outcome in advanced nonsmall cell lung cancer patients.
    Karacaoğlan V; Ada AO; Bilgen S; Çetinkaya GT; Soydaş E; Kunak CS; Alpar SM; Gülhan M; Işcan M
    Turk J Med Sci; 2017 Apr; 47(2):554-562. PubMed ID: 28425245
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer.
    Pérez-Ramírez C; Cañadas-Garre M; Molina MÁ; Robles AI; Faus-Dáder MJ; Calleja-Hernández MÁ
    Mutat Res Rev Mutat Res; 2017; 771():32-58. PubMed ID: 28342452
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function.
    Choi M; Kadara H; Zhang J; Parra ER; Rodriguez-Canales J; Gaffney SG; Zhao Z; Behrens C; Fujimoto J; Chow C; Kim K; Kalhor N; Moran C; Rimm D; Swisher S; Gibbons DL; Heymach J; Kaftan E; Townsend JP; Lynch TJ; Schlessinger J; Lee J; Lifton RP; Herbst RS; Wistuba II
    Ann Oncol; 2017 Jan; 28(1):83-89. PubMed ID: 28177435
    [TBL] [Abstract] [Full Text] [Related]  


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