Terms: = Testicular cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
15 results:
1. Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors.
Timmerman DM; Eleveld TF; Sriram S; Dorssers LCJ; Gillis AJM; Schmidtova S; Kalavska K; van de Werken HJG; Oing C; Honecker F; Mego M; Looijenga LHJ
J Clin Oncol; 2022 Sep; 40(26):3077-3087. PubMed ID: 35442716
[TBL] [Abstract] [Full Text] [Related]
2. p53 and mdm2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome.
Lobo J; Alzamora MA; Guimarães R; Cantante M; Lopes P; Braga I; Maurício J; Jerónimo C; Henrique R
Andrology; 2020 Sep; 8(5):1233-1242. PubMed ID: 32384200
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3. New insights into germ cell tumor genomics.
Lafin JT; Bagrodia A; Woldu S; Amatruda JF
Andrology; 2019 Jul; 7(4):507-515. PubMed ID: 30896089
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4. Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review.
Romano FJ; Rossetti S; Conteduca V; Schepisi G; Cavaliere C; Di Franco R; La Mantia E; Castaldo L; Nocerino F; Ametrano G; Cappuccio F; Malzone G; Montanari M; Vanacore D; Quagliariello V; Piscitelli R; Pepe MF; Berretta M; D'Aniello C; Perdonà S; Muto P; Botti G; Ciliberto G; Veneziani BM; De Falco F; Maiolino P; Caraglia M; Montella M; De Giorgi U; Facchini G
Oncotarget; 2016 Dec; 7(51):85641-85649. PubMed ID: 27821802
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5. testicular germ cell tumor genomics.
Woldu SL; Amatruda JF; Bagrodia A
Curr Opin Urol; 2017 Jan; 27(1):41-47. PubMed ID: 27584029
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6. Cisplatin resistance in germ cell tumours: models and mechanisms.
Jacobsen C; Honecker F
Andrology; 2015 Jan; 3(1):111-21. PubMed ID: 25546083
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7. Unravelling mechanisms of cisplatin sensitivity and resistance in testicular cancer.
Koster R; van Vugt MA; Timmer-Bosscha H; Gietema JA; de Jong S
Expert Rev Mol Med; 2013 Sep; 15():e12. PubMed ID: 24074238
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8. Biological markers of cisplatin resistance in advanced testicular germ cell tumours.
García-Velasco A; Durán I; García E; Tarón M; Ballestín C; Castellanos D; Cortés-Funés H; Paz-Ares L
Clin Transl Oncol; 2012 Jun; 14(6):452-7. PubMed ID: 22634534
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9. Disruption of the mdm2-p53 interaction strongly potentiates p53-dependent apoptosis in cisplatin-resistant human testicular carcinoma cells via the Fas/FasL pathway.
Koster R; Timmer-Bosscha H; Bischoff R; Gietema JA; de Jong S
Cell Death Dis; 2011 Apr; 2(4):e148. PubMed ID: 21509038
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10. p53 inactivation by mdm2 and MDMX negative feedback loops in testicular germ cell tumors.
Li B; Cheng Q; Li Z; Chen J
Cell Cycle; 2010 Apr; 9(7):1411-20. PubMed ID: 20372076
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11. MdmX is a substrate for the deubiquitinating enzyme USP2a.
Allende-Vega N; Sparks A; Lane DP; Saville MK
Oncogene; 2010 Jan; 29(3):432-41. PubMed ID: 19838211
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12. Therapeutic potential of mdm2 inhibition in malignant germ cell tumours.
Bauer S; Mühlenberg T; Leahy M; Hoiczyk M; Gauler T; Schuler M; Looijenga L
Eur Urol; 2010 Apr; 57(4):679-87. PubMed ID: 19560254
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13. The attractive Achilles heel of germ cell tumours: an inherent sensitivity to apoptosis-inducing stimuli.
Spierings DC; de Vries EG; Vellenga E; de Jong S
J Pathol; 2003 Jun; 200(2):137-48. PubMed ID: 12754734
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14. Role of P53 and mdm2 in treatment response of human germ cell tumors.
Kersemaekers AM; Mayer F; Molier M; van Weeren PC; Oosterhuis JW; Bokemeyer C; Looijenga LH
J Clin Oncol; 2002 Mar; 20(6):1551-61. PubMed ID: 11896104
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15. Differential regulation of p21waf-1/cip-1 and mdm2 by etoposide: etoposide inhibits the p53-mdm2 autoregulatory feedback loop.
Arriola EL; Lopez AR; Chresta CM
Oncogene; 1999 Jan; 18(4):1081-91. PubMed ID: 10023685
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