Terms: = Thyroid cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
16 results:
1. Downregulation of mdm2 by small interference RNA induces apoptosis and sensitizes MCF-7 breast cells to resveratrol.
Zhang NX; Ma JF; Li SQ; Yin Z; Li L
Chem Biol Drug Des; 2023 May; 101(5):1082-1088. PubMed ID: 36515454
[TBL] [Abstract] [Full Text] [Related]
2. p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through mdm2 Inhibition.
Oppel F; Shao S; Gendreizig S; Zimmerman MW; Schürmann M; Flavian VF; Goon P; Chi SN; Aster JC; Sudhoff H; Look AT
Mol Cancer Ther; 2022 Nov; 21(11):1689-1700. PubMed ID: 36099437
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3. p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With thyroid cancer and Autoimmunity.
Arena A; Stigliano A; Belcastro E; Giorda E; Rosado MM; Grossi A; Assenza MR; Moretti F; Fierabracci A
Front Immunol; 2021; 12():728381. PubMed ID: 34539667
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4. Clinical utility of the imunohistochemical co-expression of p53 and mdm2 in thyroid follicular lesions.
Martins MB; de Assis Batista F; Marcello MA; Bufalo NE; Peres KC; Morari EC; Soares FA; Vassallo J; Ward LS
Ann Diagn Pathol; 2021 Aug; 53():151766. PubMed ID: 34111705
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5. Genetic variants and risk of thyroid cancer among Iranian patients.
Jamshidi M; Farnoosh G; Mohammadi Pour S; Rafiee F; Saeedi Boroujeni A; Mahmoudian-Sani MR
Horm Mol Biol Clin Investig; 2021 Feb; 42(2):223-234. PubMed ID: 33544997
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6. IU1 suppresses proliferation of cervical cancer cells through mdm2 degradation.
Xu L; Wang J; Yuan X; Yang S; Xu X; Li K; He Y; Wei L; Zhang J; Tian Y
Int J Biol Sci; 2020; 16(15):2951-2963. PubMed ID: 33061808
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7. Over expression of CDK4 and mdm2 in a patient with recurrent ALK-negative mediastinal inflammatory myofibroblastic tumor: A case report.
Hou TC; Wu PS; Huang WY; Yang YT; Tan KT; Liu SH; Chen YJ; Chen SJ; Su YW
Medicine (Baltimore); 2020 Mar; 99(12):e19577. PubMed ID: 32195970
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8. Restoration of p53 using the novel mdm2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.
Chen H; Luo D; Zhang L; Lin X; Luo Q; Yi H; Wang J; Yan X; Li B; Chen Y; Liu X; Zhang H; Liu S; Qiu M; Yang D; Jiang N
Oncotarget; 2017 Jun; 8(26):43008-43022. PubMed ID: 28498808
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9. Non-functioning parathyroid gland carcinoma: case report.
Krvavica A; Kovacić M; Baraka I; Rudić M
Acta Clin Croat; 2011 Jun; 50(2):233-7. PubMed ID: 22263388
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10. Interactions of the hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib.
Ooi MG; Hayden PJ; Kotoula V; McMillin DW; Charalambous E; Daskalaki E; Raje NS; Munshi NC; Chauhan D; Hideshima T; Buon L; Clynes M; O'Gorman P; Richardson PG; Mitsiades CS; Anderson KC; Mitsiades N
Clin Cancer Res; 2009 Dec; 15(23):7153-60. PubMed ID: 19934289
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11. Three assays show differences in binding of wild-type and mutant p53 to unique gene sequences.
Chandrachud U; Gal S
Technol Cancer Res Treat; 2009 Dec; 8(6):445-53. PubMed ID: 19925028
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12. Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment.
Wiseman SM; Masoudi H; Niblock P; Turbin D; Rajput A; Hay J; Bugis S; Filipenko D; Huntsman D; Gilks B
Ann Surg Oncol; 2007 Feb; 14(2):719-29. PubMed ID: 17115102
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13. Molecular control of the cell cycle in cancer: biological and clinical aspects.
Møller MB
Dan Med Bull; 2003 May; 50(2):118-38. PubMed ID: 12812137
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14. The histone deacetylase inhibitor FR901228 (desipeptide) restores expression and function of pseudo-null p53.
Kitazono M; Bates S; Fok P; Fojo T; Blagosklonny MV
Cancer Biol Ther; 2002; 1(6):665-8. PubMed ID: 12642691
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15. The mdm2 proto-oncogene sensitizes human medullary thyroid carcinoma cells to ionizing radiation.
Dilla T; Romero J; Sanstisteban P; Velasco JA
Oncogene; 2002 Apr; 21(15):2376-86. PubMed ID: 11948421
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16. Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells.
Blagosklonny MV; Giannakakou P; Wojtowicz M; Romanova LY; Ain KB; Bates SE; Fojo T
J Clin Endocrinol Metab; 1998 Jul; 83(7):2516-22. PubMed ID: 9661637
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