Terms: = Thyroid cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
16 results:
1. Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Yuan Q; Fan Y; Liu Z; Wang X; Jia M; Dong Y; Geng Z; Zheng J; Lu X
Apoptosis; 2023 Oct; 28(9-10):1315-1331. PubMed ID: 37336836
[TBL] [Abstract] [Full Text] [Related]
2. Dsg2-mediated c-Met activation in anaplastic thyroid cancer motility and invasion.
Lee K; Lee SH; Kim W; Lee J; Park JG; Kim JS; Kim JT; Kang YE; Shong M; Lee HJ; Kim JM; Kim WG; Koo BS; Kim KS; Min JK
Endocr Relat Cancer; 2020 Nov; 27(11):601-614. PubMed ID: 33022637
[TBL] [Abstract] [Full Text] [Related]
3. Antagonistic effects of rac1 and tumor-related rac1b on NIS expression in thyroid.
Faria M; Félix D; Domingues R; Bugalho MJ; Matos P; Silva AL
J Mol Endocrinol; 2019 Nov; 63(4):309-320. PubMed ID: 31590142
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4. KRAS G12V Mutation in Acquired Resistance to Combined BRAF and MEK Inhibition in Papillary thyroid cancer.
Owen DH; Konda B; Sipos J; Liu T; Webb A; Ringel MD; Timmers CD; Shah MH
J Natl Compr Canc Netw; 2019 May; 17(5):409-413. PubMed ID: 31085763
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5. MicroRNA 483-3p targets Pard3 to potentiate TGF-β1-induced cell migration, invasion, and epithelial-mesenchymal transition in anaplastic thyroid cancer cells.
Zhang X; Liu L; Deng X; Li D; Cai H; Ma Y; Jia C; Wu B; Fan Y; Lv Z
Oncogene; 2019 Jan; 38(5):699-715. PubMed ID: 30171257
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6. Ginsenoside Rg3 Inhibition of thyroid cancer Metastasis Is Associated with Alternation of Actin Skeleton.
Wu W; Zhou Q; Zhao W; Gong Y; Su A; Liu F; Liu Y; Li Z; Zhu J
J Med Food; 2018 Sep; 21(9):849-857. PubMed ID: 30136914
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7. Tiam1 promotes thyroid carcinoma metastasis by modulating EMT via Wnt/β-catenin signaling.
Liu L; Wu B; Cai H; Li D; Ma Y; Zhu X; Lv Z; Fan Y; Zhang X
Exp Cell Res; 2018 Jan; 362(2):532-540. PubMed ID: 29277502
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8. Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic thyroid cancer.
Chen MC; Tsai YC; Tseng JH; Liou JJ; Horng S; Wen HC; Fan YC; Zhong WB; Hsu SP
Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29236027
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9. An anti-cancer WxxxE-containing azurin polypeptide inhibits rac1-dependent STAT3 and ERK/GSK-3β signaling in breast cancer cells.
Zhang Z; Luo Z; Min W; Zhang L; Wu Y; Hu X
Oncotarget; 2017 Jun; 8(26):43091-43103. PubMed ID: 28549350
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10. EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary thyroid cancer.
Li JJ; Sun ZJ; Yuan YM; Yin FF; Bian YG; Long LY; Zhang XL; Xie D
J Biol Chem; 2017 Jan; 292(3):1112-1121. PubMed ID: 27986811
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11. Regulation of sodium iodide symporter gene expression by rac1/p38β mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells.
Kogai T; Liu YY; Mody K; Shamsian DV; Brent GA
J Biol Chem; 2012 Jan; 287(5):3292-300. PubMed ID: 22157753
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12. Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway.
Zhong WB; Hsu SP; Ho PY; Liang YC; Chang TC; Lee WS
Biochem Pharmacol; 2011 Dec; 82(11):1663-72. PubMed ID: 21907187
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13. Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCdelta-independent destabilization of the focal adhesion complex.
Lin CJ; Lin CY; Chen Y; Huang SH; Wang SM
J Cell Biochem; 2010 May; 110(2):428-37. PubMed ID: 20225271
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14. Tumor cytotoxicity and endothelial Rac inhibition induced by TNP-470 in anaplastic thyroid cancer.
Nahari D; Satchi-Fainaro R; Chen M; Mitchell I; Task LB; Liu Z; Kihneman J; Carroll AB; Terada LS; Nwariaku FE
Mol Cancer Ther; 2007 Apr; 6(4):1329-37. PubMed ID: 17431111
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15. Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling.
Zhong WB; Liang YC; Wang CY; Chang TC; Lee WS
Endocr Relat Cancer; 2005 Sep; 12(3):615-29. PubMed ID: 16172195
[TBL] [Abstract] [Full Text] [Related]
16. Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis.
Zhong WB; Wang CY; Chang TC; Lee WS
Endocrinology; 2003 Sep; 144(9):3852-9. PubMed ID: 12933658
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