BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Uterine cancer AND EZH2, ENX-1, 2146, ENSG00000106462, Q15910, MGC9169 AND Treatment
23 results:

  • 1. Compound AC1Q3QWB upregulates CDKN1A and SOX17 by interrupting the HOTAIR-ezh2 interaction and enhances the efficacy of tazemetostat in endometrial cancer.
    Chen L; Zheng X; Liu W; Sun Y; Zhao S; Tian L; Tian W; Xue F; Kang C; Wang Y
    Cancer Lett; 2023 Dec; 578():216445. PubMed ID: 37866545
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. ezh2 activates Wnt/β-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate.
    Ali M; Stone D; Laknaur A; Yang Q; Al-Hendy A
    F S Sci; 2023 Aug; 4(3):239-256. PubMed ID: 37182601
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Mouse uterine stem cells are affected by endocrine disruption and initiate uteropathies.
    Singh P; Bhartiya D
    Reproduction; 2023 Mar; 165(3):249-268. PubMed ID: 36488194
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. USP7 inhibits TIMP2 by up-regulating the expression of ezh2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer.
    Li N; Geng F; Liang SM; Qin X
    Cell Signal; 2022 Aug; 96():110351. PubMed ID: 35523402
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting ezh2.
    Chen R; Gan Q; Zhao S; Zhang D; Wang S; Yao L; Yuan M; Cheng J
    BMC Cancer; 2022 May; 22(1):488. PubMed ID: 35505294
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Sodium Valproate Modulates the Methylation Status of Lysine Residues 4, 9 and 27 in Histone H3 of HeLa Cells.
    Rocha MA; de Campos Vidal B; Mello MLS
    Curr Mol Pharmacol; 2023; 16(2):197-210. PubMed ID: 35297358
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. TCF3 is epigenetically silenced by ezh2 and DNMT3B and functions as a tumor suppressor in endometrial cancer.
    Gui T; Liu M; Yao B; Jiang H; Yang D; Li Q; Zeng X; Wang Y; Cao J; Deng Y; Li X; Xu P; Zhou L; Li D; Wang Z; Zen K; Huang DCS; Chen B; Wan G; Zhao Q
    Cell Death Differ; 2021 Dec; 28(12):3316-3328. PubMed ID: 34175897
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Long non-coding RNA DLEU2 drives EMT and glycolysis in endometrial cancer through HK2 by competitively binding with miR-455 and by modulating the ezh2/miR-181a pathway.
    Dong P; Xiong Y; Konno Y; Ihira K; Kobayashi N; Yue J; Watari H
    J Exp Clin Cancer Res; 2021 Jun; 40(1):216. PubMed ID: 34174908
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Long non-coding RNA ARAP1-AS1 promotes the proliferation and migration in cervical cancer through epigenetic regulation of DUSP5.
    Min H; He W
    Cancer Biol Ther; 2020 Oct; 21(10):907-914. PubMed ID: 32985327
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. LncRNA PCAT1 promotes metastasis of endometrial carcinoma through epigenetical downregulation of E-cadherin associated with methyltransferase ezh2.
    Zhang C; Shao S; Zhang Y; Wang L; Liu J; Fang F; Li P; Wang B
    Life Sci; 2020 Feb; 243():117295. PubMed ID: 31927050
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. The lncRNA TUG1 modulates proliferation in trophoblast cells via epigenetic suppression of RND3.
    Xu Y; Ge Z; Zhang E; Zuo Q; Huang S; Yang N; Wu D; Zhang Y; Chen Y; Xu H; Huang H; Jiang Z; Sun L
    Cell Death Dis; 2017 Oct; 8(10):e3104. PubMed ID: 29022920
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Oncogenic histone methyltransferase ezh2: A novel prognostic marker with therapeutic potential in endometrial cancer.
    Oki S; Sone K; Oda K; Hamamoto R; Ikemura M; Maeda D; Takeuchi M; Tanikawa M; Mori-Uchino M; Nagasaka K; Miyasaka A; Kashiyama T; Ikeda Y; Arimoto T; Kuramoto H; Wada-Hiraike O; Kawana K; Fukayama M; Osuga Y; Fujii T
    Oncotarget; 2017 Jun; 8(25):40402-40411. PubMed ID: 28418882
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Theanine from tea and its semi-synthetic derivative TBrC suppress human cervical cancer growth and migration by inhibiting EGFR/Met-Akt/NF-κB signaling.
    Liu J; Sun Y; Zhang H; Ji D; Wu F; Tian H; Liu K; Zhang Y; Wu B; Zhang G
    Eur J Pharmacol; 2016 Nov; 791():297-307. PubMed ID: 27612630
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Identification of Polycomb Group Protein ezh2-Mediated DNA Mismatch Repair Gene MSH2 in Human uterine Fibroids.
    Yang Q; Laknaur A; Elam L; Ismail N; Gavrilova-Jordan L; Lue J; Diamond MP; Al-Hendy A
    Reprod Sci; 2016 Oct; 23(10):1314-25. PubMed ID: 27036951
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. LncRNAs: key players and novel insights into cervical cancer.
    Peng L; Yuan X; Jiang B; Tang Z; Li GC
    Tumour Biol; 2016 Mar; 37(3):2779-88. PubMed ID: 26715267
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Interference with endogenous ezh2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression.
    Cai L; Wang Z; Liu D
    Tumour Biol; 2016 May; 37(5):6359-69. PubMed ID: 26631032
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. ARID1A gene mutation in ovarian and endometrial cancers (Review).
    Takeda T; Banno K; Okawa R; Yanokura M; Iijima M; Irie-Kunitomi H; Nakamura K; Iida M; Adachi M; Umene K; Nogami Y; Masuda K; Kobayashi Y; Tominaga E; Aoki D
    Oncol Rep; 2016 Feb; 35(2):607-13. PubMed ID: 26572704
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. The polycomb group protein enhancer of zeste 2 is a novel therapeutic target for cervical cancer.
    Ding M; Zhang H; Li Z; Wang C; Chen J; Shi L; Xu D; Gao Y
    Clin Exp Pharmacol Physiol; 2015 May; 42(5):458-64. PubMed ID: 25739318
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Changes in the transcriptome of the human endometrial Ishikawa cancer cell line induced by estrogen, progesterone, tamoxifen, and mifepristone (RU486) as detected by RNA-sequencing.
    Tamm-Rosenstein K; Simm J; Suhorutshenko M; Salumets A; Metsis M
    PLoS One; 2013; 8(7):e68907. PubMed ID: 23874806
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Overexpression of enhancer of zeste homolog 2 (ezh2) and focal adhesion kinase (FAK) in high grade endometrial carcinoma.
    Zhou J; Roh JW; Bandyopadhyay S; Chen Z; Munkarah AR; Hussein Y; Alosh B; Jazaerly T; Hayek K; Semaan A; Sood AK; Ali-Fehmi R
    Gynecol Oncol; 2013 Feb; 128(2):344-8. PubMed ID: 22871469
    [TBL] [Abstract] [Full Text] [Related]  


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