Terms: = Uterine cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1 AND Treatment
19 results:
1. AC010883.5 promotes cell proliferation, invasion, migration, and epithelial-to-mesenchymal transition in cervical cancer by modulating the MAPK signaling pathway.
Gan Q; Huang X; Zhao W; Liu H; Xu Y; Zhang X; Cheng J; Chen R
BMC Cancer; 2023 Apr; 23(1):364. PubMed ID: 37081411
[TBL] [Abstract] [Full Text] [Related]
2. Cobimetinib Sensitizes Cervical cancer to Paclitaxel via Suppressing Paclitaxel-Induced ERK Activation.
Liu Y; Zhao R; Qin X; Mao X; Li Q; Fang S
Pharmacology; 2022; 107(7-8):398-405. PubMed ID: 35526525
[TBL] [Abstract] [Full Text] [Related]
3. Epidermal growth factor receptor regulates fibrinolytic pathway elements in cervical cancer: functional and prognostic implications.
Gomes FG; Almeida VH; Martins-Cardoso K; Martins-Dinis MMDC; Rondon AMR; Melo AC; Tilli TM; Monteiro RQ
Braz J Med Biol Res; 2021; 54(6):e10754. PubMed ID: 33886813
[TBL] [Abstract] [Full Text] [Related]
4. Inhibiting ubiquitin conjugating enzyme E2 N by microRNA-590-3p reduced cell growth of cervical carcinoma.
Song TT; Xu F; Wang W
Kaohsiung J Med Sci; 2020 Jul; 36(7):501-507. PubMed ID: 32196955
[TBL] [Abstract] [Full Text] [Related]
5. RCE‑4, a potential anti‑cervical cancer drug isolated from Reineckia carnea, induces autophagy via the dual blockade of PI3K and ERK pathways in cervical cancer CaSki cells.
Xiang W; Zhang RJ; Jin GL; Tian L; Cheng F; Wang JZ; Xing XF; Xi W; Tang SJ; Chen JF
Int J Mol Med; 2020 Jan; 45(1):245-254. PubMed ID: 31746346
[TBL] [Abstract] [Full Text] [Related]
6. BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway.
Wang F; Chen Q; Huang G; Guo X; Li N; Li Y; Li B
BMC Cancer; 2018 Nov; 18(1):1128. PubMed ID: 30445932
[TBL] [Abstract] [Full Text] [Related]
7. A Novel Target of p53, TCF21, Can Respond to Hypoxia by MAPK Pathway Inactivation in uterine Corpus Endometrial Carcinoma.
Li Q; Lei Y; Du W
DNA Cell Biol; 2018 May; 37(5):473-480. PubMed ID: 29608330
[TBL] [Abstract] [Full Text] [Related]
8. Praeruptorin A Inhibits Human Cervical cancer Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling.
Wu MH; Lin CL; Chiou HL; Yang SF; Lin CY; Liu CJ; Hsieh YH
Int J Mol Sci; 2017 Dec; 19(1):. PubMed ID: 29267213
[TBL] [Abstract] [Full Text] [Related]
9. Pioglitazone induces cell growth arrest and activates mitochondrial apoptosis in human uterine leiomyosarcoma cells by a peroxisome proliferator-activated receptor γ-independent mechanism.
Lützen U; Zhao Y; Lucht K; Zuhayra M; Marx M; Cascorbi I; Culman J
Naunyn Schmiedebergs Arch Pharmacol; 2017 Jan; 390(1):37-48. PubMed ID: 27664035
[TBL] [Abstract] [Full Text] [Related]
10. Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models.
Schrauwen S; Depreeuw J; Coenegrachts L; Hermans E; Lambrechts D; Amant F
Gynecol Oncol; 2015 Jul; 138(1):165-73. PubMed ID: 25933683
[TBL] [Abstract] [Full Text] [Related]
11. Estrogen induction of telomerase activity through regulation of the mitogen-activated protein kinase (MAPK) dependent pathway in human endometrial cancer cells.
Zhou C; Steplowski TA; Dickens HK; Malloy KM; Gehrig PA; Boggess JF; Bae-Jump VL
PLoS One; 2013; 8(2):e55730. PubMed ID: 23409030
[TBL] [Abstract] [Full Text] [Related]
12. Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3-dependent pathway.
Ying TH; Yang SF; Tsai SJ; Hsieh SC; Huang YC; Bau DT; Hsieh YH
Arch Toxicol; 2012 Feb; 86(2):263-73. PubMed ID: 21964635
[TBL] [Abstract] [Full Text] [Related]
13. Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells.
Tong JS; Zhang QH; Huang X; Fu XQ; Qi ST; Wang YP; Hou Y; Sheng J; Sun QY
PLoS One; 2011 Mar; 6(3):e16781. PubMed ID: 21408143
[TBL] [Abstract] [Full Text] [Related]
14. Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation.
Rosenberger S; De-Castro Arce J; Langbein L; Steenbergen RD; Rösl F
Proc Natl Acad Sci U S A; 2010 Apr; 107(15):7006-11. PubMed ID: 20351270
[TBL] [Abstract] [Full Text] [Related]
15. Combination of cetuximab with chemoradiation, trastuzumab or MAPK inhibitors: mechanisms of sensitisation of cervical cancer cells.
Meira DD; de Almeida VH; Mororó JS; Nóbrega I; Bardella L; Silva RL; Albano RM; Ferreira CG
Br J Cancer; 2009 Sep; 101(5):782-91. PubMed ID: 19654571
[TBL] [Abstract] [Full Text] [Related]
16. The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway.
Javvadi P; Segan AT; Tuttle SW; Koumenis C
Mol Pharmacol; 2008 May; 73(5):1491-501. PubMed ID: 18252805
[TBL] [Abstract] [Full Text] [Related]
17. Profile of ovarian cancer patients seeking information from a web-based decision support program.
Markman M; Markman MR; Belland A; Petersen J
J Womens Health (Larchmt); 2006 Apr; 15(3):312-8. PubMed ID: 16620190
[TBL] [Abstract] [Full Text] [Related]
18. Fibromodulin is expressed in leiomyoma and myometrium and regulated by gonadotropin-releasing hormone analogue therapy and TGF-beta through Smad and MAPK-mediated signalling.
Levens E; Luo X; Ding L; Williams RS; Chegini N
Mol Hum Reprod; 2005 Jul; 11(7):489-94. PubMed ID: 16123076
[TBL] [Abstract] [Full Text] [Related]
19. Estrogen receptor, growth factor receptor and protooncogene protein activities and possible signal transduction crosstalk in estrogen dependent and independent breast cancer cell lines.
Mohamood AS; Gyles P; Balan KV; Hollis VW; Eckberg WR; Asseffa A; Han Z; Wyche JH; Anderson WA
J Submicrosc Cytol Pathol; 1997 Jan; 29(1):1-17. PubMed ID: 9066137
[TBL] [Abstract] [Full Text] [Related]
