BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Uterine cancer AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
8 results:

  • 1. uterine leiomyosarcomas harboring map2k4 gene amplification are sensitive in vivo to PLX8725, a novel map2k4 inhibitor.
    McNamara B; Harold J; Manavella D; Bellone S; Mutlu L; Hartwich TMP; Zipponi M; Yang-Hartwich Y; Demirkiran C; Verzosa MSZ; Yang K; Choi J; Dong W; Buza N; Hui P; Altwerger G; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Burton EA; Inagaki H; Albers A; Zhang C; Bollag G; Schlessinger J; Santin AD
    Gynecol Oncol; 2023 May; 172():65-71. PubMed ID: 36958197
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Integrated mutational landscape analysis of uterine leiomyosarcomas.
    Choi J; Manzano A; Dong W; Bellone S; Bonazzoli E; Zammataro L; Yao X; Deshpande A; Zaidi S; Guglielmi A; Gnutti B; Nagarkatti N; Tymon-Rosario JR; Harold J; Mauricio D; Zeybek B; Menderes G; Altwerger G; Jeong K; Zhao S; Buza N; Hui P; Ravaggi A; Bignotti E; Romani C; Todeschini P; Zanotti L; Odicino F; Pecorelli S; Ardighieri L; Bilguvar K; Quick CM; Silasi DA; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Imielinski M; Schwartz PE; Alexandrov LB; Lifton RP; Schlessinger J; Santin AD
    Proc Natl Acad Sci U S A; 2021 Apr; 118(15):. PubMed ID: 33876771
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Gene Expression Analysis Identifies Novel Targets for Cervical cancer Therapy.
    Roszik J; Ring KL; Wani KM; Lazar AJ; Yemelyanova AV; Soliman PT; Frumovitz M; Jazaeri AA
    Front Immunol; 2018; 9():2102. PubMed ID: 30283446
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. [Coexpression of map2k4 and vimentin proteins in human endometrial carcinoma and its clinicopathological significance].
    Liu CH; Jiang QP; Lin D; Chen W; Xiao YY; Lin L; Deng YR; Jiang HP; Guo SQ
    Nan Fang Yi Ke Da Xue Xue Bao; 2016 Feb; 37(2):157-164. PubMed ID: 28219857
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The association between -1304T>G polymorphism in the promoter of mitogen-activated protein kinase kinase 4 gene and the risk of cervical cancer in Chinese population.
    Hu M; Zheng J; Zhang L; Jiang L; You Y; Jiang M; Li H
    DNA Cell Biol; 2012 Jul; 31(7):1167-73. PubMed ID: 22335172
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Functional and clinicopathological analysis of loss of mkk4 expression in endometrial cancer.
    Ishikawa M; Nakayama K; Rahman MT; Rahman M; Katagiri A; Iida K; Miyazaki K
    Oncology; 2010; 79(3-4):238-46. PubMed ID: 21372598
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. c-Jun N-terminal kinase regulates apoptosis in endometrial cancer cells.
    Reno EM; Haughian JM; Jackson TA; Thorne AM; Bradford AP
    Apoptosis; 2009 Jun; 14(6):809-20. PubMed ID: 19424800
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Opposing roles of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in the cellular response to ionizing radiation in human cervical cancer cells.
    Kim MJ; Choi SY; Park IC; Hwang SG; Kim C; Choi YH; Kim H; Lee KH; Lee SJ
    Mol Cancer Res; 2008 Nov; 6(11):1718-31. PubMed ID: 19010820
    [TBL] [Abstract] [Full Text] [Related]  


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