Terms: = Uterine cancer AND MED12, Q93074, TRAP230, TNRC11, OKS, KIAA0192, HOPA, FGS1, CAGH45, ARC240, 9968 AND Treatment
24 results:
1. med12 mutation activates the tryptophan/kynurenine/AHR pathway to promote growth of uterine leiomyomas.
Zuberi A; Huang Y; Dotts AJ; Wei H; Coon JS; Liu S; Iizuka T; Wu O; Sotos O; Saini P; Chakravarti D; Boyer TG; Dai Y; Bulun SE; Yin P
JCI Insight; 2023 Sep; 8(18):. PubMed ID: 37607000
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2. med12 mutations in uterine leiomyomas: prediction of volume reduction by gonadotropin-releasing hormone agonists.
Nagai K; Asano R; Sekiguchi F; Asai-Sato M; Miyagi Y; Miyagi E
Am J Obstet Gynecol; 2023 Feb; 228(2):207.e1-207.e9. PubMed ID: 36150519
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3. Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate.
Kolterud Å; Välimäki N; Kuisma H; Patomo J; Ilves ST; Mäkinen N; Kaukomaa J; Palin K; Kaasinen E; Karhu A; Pasanen A; Bützow R; Heikinheimo O; Kopp Kallner H; Aaltonen LA
Hum Mol Genet; 2023 Mar; 32(7):1063-1071. PubMed ID: 36048862
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4. Guizhi Fuling Capsule inhibits uterine fibroids growth by modulating med12-mediated Wnt/β-Catenin signaling pathway.
Chen L; Chen H; Yang Q; Jiang Y; Liu L; Yu H; Chen Y; Li J; Chen N; Wang H; Wang Q
J Ethnopharmacol; 2022 May; 290():115115. PubMed ID: 35181487
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5. uterine Fibroids: Hiding in Plain Sight.
Stewart EA; Nowak RA
Physiology (Bethesda); 2022 Jan; 37(1):16-27. PubMed ID: 34964688
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6. Long Noncoding RNA MIAT Modulates the Extracellular Matrix Deposition in Leiomyomas by Sponging MiR-29 Family.
Chuang TD; Quintanilla D; Boos D; Khorram O
Endocrinology; 2021 Nov; 162(11):. PubMed ID: 34491311
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7. Tryptophan catabolism is dysregulated in leiomyomas.
Chuang TD; Quintanilla D; Boos D; Khorram O
Fertil Steril; 2021 Oct; 116(4):1160-1171. PubMed ID: 34116832
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8. Wnt/β-catenin signaling pathway in uterine leiomyoma: role in tumor biology and targeting opportunities.
El Sabeh M; Saha SK; Afrin S; Islam MS; Borahay MA
Mol Cell Biochem; 2021 Sep; 476(9):3513-3536. PubMed ID: 33999334
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9. Vitamin D as an effective treatment in human uterine leiomyomas independent of mediator complex subunit 12 mutation.
Corachán A; Trejo MG; Carbajo-García MC; Monleón J; Escrig J; Faus A; Pellicer A; Cervelló I; Ferrero H
Fertil Steril; 2021 Feb; 115(2):512-521. PubMed ID: 33036796
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10. Pathogenomics of uterine Fibroids Development.
Baranov VS; Osinovskaya NS; Yarmolinskaya MI
Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31817606
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11. H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas.
Cao T; Jiang Y; Wang Z; Zhang N; Al-Hendy A; Mamillapalli R; Kallen AN; Kodaman P; Taylor HS; Li D; Huang Y
Oncogene; 2019 Jul; 38(27):5356-5366. PubMed ID: 31089260
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12. Expression of erythropoietin messenger ribonucleic acid in wild-type med12 uterine leiomyomas under estrogenic influence: new insights into related growth disparities.
Asano R; Asai-Sato M; Matsukuma S; Mizushima T; Taguri M; Yoshihara M; Inada M; Fukui A; Suzuki Y; Miyagi Y; Miyagi E
Fertil Steril; 2019 Jan; 111(1):178-185. PubMed ID: 30554729
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13. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review).
Katoh M
Int J Mol Med; 2018 Aug; 42(2):713-725. PubMed ID: 29786110
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14. Proteomic Analysis Identifies Tenascin-C Expression Is Upregulated in uterine Fibroids.
Jamaluddin MFB; Nagendra PB; Nahar P; Oldmeadow C; Tanwar PS
Reprod Sci; 2019 Apr; 26(4):476-486. PubMed ID: 29730954
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15. Clinical, pathologic, cytogenetic, and molecular profiling in self-identified black women with uterine leiomyomata.
Hayden MA; Ordulu Z; Gallagher CS; Quade BJ; Anchan RM; Middleton NR; Srouji SS; Stewart EA; Morton CC
Cancer Genet; 2018 Apr; 222-223():1-8. PubMed ID: 29666002
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16. Clinicopathologic Features and Genetic Alterations of a Primary Osteosarcoma of the uterine Corpus.
Zheng G; Richmond A; Liu C; Berrebi A; Pallavajjala A; Haley L; Stone RL; McCarthy E; Vang R; Xing D
Int J Gynecol Pathol; 2019 Sep; 38(5):414-419. PubMed ID: 29629977
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17. Integrated genome analysis of uterine leiomyosarcoma to identify novel driver genes and targetable pathways.
Cuppens T; Moisse M; Depreeuw J; Annibali D; Colas E; Gil-Moreno A; Huvila J; Carpén O; Zikán M; Matias-Guiu X; Moerman P; Croce S; Lambrechts D; Amant F
Int J Cancer; 2018 Mar; 142(6):1230-1243. PubMed ID: 29063609
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18. Catechol-O-methyltransferase Val158Met polymorphism is associated with increased risk of multiple uterine leiomyomas either positive or negative for
Dzhemlikhanova LK; Efimova OA; Osinovskaya NS; Parfenyev SE; Niauri DA; Sultanov IY; Malysheva OV; Pendina AA; Shved NY; Ivashchenko TE; Yarmolinskaya MI; Kakhiani MI; Gorovaya EA; Tkachenko AN; Baranov VS
J Clin Pathol; 2017 Mar; 70(3):233-236. PubMed ID: 27491313
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19. Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth.
Commandeur AE; Styer AK; Teixeira JM
Hum Reprod Update; 2015; 21(5):593-615. PubMed ID: 26141720
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20. Selective genetic analysis of myoma pseudocapsule and potential biological impact on uterine fibroid medical therapy.
Di Tommaso S; Massari S; Malvasi A; Vergara D; Maffia M; Greco M; Tinelli A
Expert Opin Ther Targets; 2015 Jan; 19(1):7-12. PubMed ID: 25363374
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