BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Uterine cancer AND POLE, POLE1, 5426, FLJ21434, DKFZp434F222, ENSG00000177084 AND Clinical Outcome
15 results:

  • 1. Evaluation of somatic mutations in cervicovaginal samples as a non-invasive method for the detection and molecular classification of endometrial cancer.
    Pelegrina B; Paytubi S; Marin F; Martínez JM; Carmona Á; Frias-Gomez J; Peremiquel-Trillas P; Dorca E; Zanca A; López-Querol M; Onieva I; Benavente Y; Barahona M; Fernandez-Gonzalez S; De Francisco J; Caño V; Vidal A; Pijuan L; Canet-Hermida J; Dueñas N; Brunet J; Pineda M; Matias-Guiu X; Ponce J; Bosch FX; De Sanjosé S; Alemany L; Costas L
    EBioMedicine; 2023 Aug; 94():104716. PubMed ID: 37480623
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Pure and mixed clear cell carcinoma of the endometrium: A molecular and immunohistochemical analysis study.
    Reijnen C; Vrede SW; Eijkelenboom A; Draak R; Sweegers S; Snijders MPLM; van Gestel P; Pijnenborg JMA; Bulten J; Küsters-Vandevelde HVN
    Cancer Med; 2023 Jun; 12(11):12365-12376. PubMed ID: 37081760
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. clinical impact of genetic alterations of CTNNB1 in patients with grade 3 endometrial endometrioid carcinoma.
    Kobayashi Kato M; Asami Y; Takayanagi D; Matsuda M; Shimada Y; Hiranuma K; Kuno I; Komatsu M; Hamamoto R; Matsumoto K; Ishikawa M; Kohno T; Kato T; Shiraishi K; Yoshida H
    Cancer Sci; 2022 May; 113(5):1712-1721. PubMed ID: 35278272
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Prognostic relevance of the molecular classification in high-grade endometrial cancer for patients staged by lymphadenectomy and without adjuvant treatment.
    Leon-Castillo A; Horeweg N; Peters EEM; Rutten T; Ter Haar N; Smit VTHBM; Kroon CD; Boennelycke M; Hogdall E; Hogdall C; Nout RRA; Creutzberg CL; Ortoft G; Bosse T
    Gynecol Oncol; 2022 Mar; 164(3):577-586. PubMed ID: 35078648
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. A Multiplex SNaPshot Assay is a Rapid and Cost-Effective Method for Detecting pole Exonuclease Domain Mutations in Endometrial Carcinoma.
    Devereaux KA; Steiner DF; Ho C; Gomez AJ; Gilks B; Longacre TA; Zehnder JL; Howitt BE; Suarez CJ
    Int J Gynecol Pathol; 2022 Nov; 41(6):541-551. PubMed ID: 34907997
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome.
    Hollis RL; Thomson JP; Stanley B; Churchman M; Meynert AM; Rye T; Bartos C; Iida Y; Croy I; Mackean M; Nussey F; Okamoto A; Semple CA; Gourley C; Herrington CS
    Nat Commun; 2020 Oct; 11(1):4995. PubMed ID: 33020491
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular profiling identifies synchronous endometrial and ovarian cancers as metastatic endometrial cancer with favorable clinical outcome.
    Reijnen C; Küsters-Vandevelde HVN; Ligtenberg MJL; Bulten J; Oosterwegel M; Snijders MPLM; Sweegers S; de Hullu JA; Vos MC; van der Wurff AAM; van Altena AM; Eijkelenboom A; Pijnenborg JMA
    Int J Cancer; 2020 Jul; 147(2):478-489. PubMed ID: 32022266
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Clinicopathological and molecular characterisation of 'multiple-classifier' endometrial carcinomas.
    León-Castillo A; Gilvazquez E; Nout R; Smit VT; McAlpine JN; McConechy M; Kommoss S; Brucker SY; Carlson JW; Epstein E; Rau TT; Soslow RA; Ganesan R; Matias-Guiu X; Oliva E; Harrison BT; Church DN; Gilks CB; Bosse T
    J Pathol; 2020 Mar; 250(3):312-322. PubMed ID: 31829447
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Germline
    de Jonge MM; Ritterhouse LL; de Kroon CD; Vreeswijk MPG; Segal JP; Puranik R; Hollema H; Rookus MA; van Asperen CJ; van Leeuwen FE; Smit VTHBM; Howitt BE; Bosse T;
    Clin Cancer Res; 2019 Dec; 25(24):7517-7526. PubMed ID: 31492746
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups.
    Parra-Herran C; Lerner-Ellis J; Xu B; Khalouei S; Bassiouny D; Cesari M; Ismiil N; Nofech-Mozes S
    Mod Pathol; 2017 Dec; 30(12):1748-1759. PubMed ID: 28776572
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Markers of the p53 pathway further refine molecular profiling in high-risk endometrial cancer: A TransPORTEC initiative.
    Edmondson RJ; Crosbie EJ; Nickkho-Amiry M; Kaufmann A; Stelloo E; Nijman HW; Leary A; Auguste A; Mileshkin L; Pollock P; MacKay HJ; Powell ME; Bosse T; Creutzberg CL; Kitchener HC
    Gynecol Oncol; 2017 Aug; 146(2):327-333. PubMed ID: 28511869
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Chromatin remodelling and DNA repair genes are frequently mutated in endometrioid endometrial carcinoma.
    García-Sanz P; Triviño JC; Mota A; Pérez López M; Colás E; Rojo-Sebastián A; García Á; Gatius S; Ruiz M; Prat J; López-López R; Abal M; Gil-Moreno A; Reventós J; Matias-Guiu X; Moreno-Bueno G
    Int J Cancer; 2017 Apr; 140(7):1551-1563. PubMed ID: 27997699
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. pole Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial cancer.
    van Gool IC; Eggink FA; Freeman-Mills L; Stelloo E; Marchi E; de Bruyn M; Palles C; Nout RA; de Kroon CD; Osse EM; Klenerman P; Creutzberg CL; Tomlinson IP; Smit VT; Nijman HW; Bosse T; Church DN
    Clin Cancer Res; 2015 Jul; 21(14):3347-3355. PubMed ID: 25878334
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Prognostic significance of pole proofreading mutations in endometrial cancer.
    Church DN; Stelloo E; Nout RA; Valtcheva N; Depreeuw J; ter Haar N; Noske A; Amant F; Tomlinson IP; Wild PJ; Lambrechts D; Jürgenliemk-Schulz IM; Jobsen JJ; Smit VT; Creutzberg CL; Bosse T
    J Natl Cancer Inst; 2015 Jan; 107(1):402. PubMed ID: 25505230
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. pole exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium.
    Meng B; Hoang LN; McIntyre JB; Duggan MA; Nelson GS; Lee CH; Köbel M
    Gynecol Oncol; 2014 Jul; 134(1):15-9. PubMed ID: 24844595
    [TBL] [Abstract] [Full Text] [Related]  


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