Terms: = Uterine cancer AND SPOP, TEF2, 8405, ENSG00000121067, O43791
21 results:
1. Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via spop/ERα axis.
Ge Y; Jin J; Chen G; Li J; Ye M; Jin X
Cell Commun Signal; 2023 Oct; 21(1):303. PubMed ID: 37904149
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2. Opposing Roles of
Cavalcante L; Deshmukh SK; Ribeiro JR; Carneiro BA; Dizon DS; Angara K; Mattox T; Wu S; Xiu J; Walker P; Oberley M; Nabhan C; Huang H; Antonarakis ES
JCO Precis Oncol; 2023 Sep; 7():e2300088. PubMed ID: 37677121
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3. Extrauterine Mesonephric-like Carcinoma: A Comprehensive Single Institution Study of 33 Cases.
Euscher ED; Marques-Piubelli ML; Ramalingam P; Wistuba I; Lawson BC; Frumovitz M; Malpica A
Am J Surg Pathol; 2023 Jun; 47(6):635-648. PubMed ID: 37026792
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4. spop is essential for DNA replication licensing through maintaining translation of CDT1 and CDC6 in HaCaT cells.
Sanada S; Maekawa M; Tate S; Nakaoka H; Fujisawa Y; Sayama K; Higashiyama S
Biochem Biophys Res Commun; 2023 Apr; 651():30-38. PubMed ID: 36791496
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5. Deregulation of spop in cancer.
Zhang H; Jin X; Huang H
Cancer Res; 2023 Feb; 83(4):489-499. PubMed ID: 36512624
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6. spop mutations promote tumor immune escape in endometrial cancer via the IRF1-PD-L1 axis.
Gao K; Shi Q; Gu Y; Yang W; He Y; Lv Z; Ding Y; Cao W; Wang C; Wan X
Cell Death Differ; 2023 Feb; 30(2):475-487. PubMed ID: 36481790
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7. spop promotes cervical cancer progression by inducing the movement of PD-1 away from PD-L1 in spatial localization.
Wu J; Wu Y; Guo Q; Chen S; Wang S; Wu X; Zhu J; Ju X
J Transl Med; 2022 Aug; 20(1):384. PubMed ID: 36042498
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8. Degradation of DRAK1 by CUL3/spop E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells.
Pang K; Lee J; Kim J; Park J; Park Y; Hong E; An H; Ooshima A; Son M; Park KS; Cho JH; Lee C; Song YS; Yang KM; Kim SJ
Cell Death Dis; 2022 Feb; 13(2):169. PubMed ID: 35194034
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9. Clinicopathologic and Genomic Analysis of
Momeni-Boroujeni A; Dahoud W; Vanderbilt CM; Chiang S; Murali R; Rios-Doria EV; Alektiar KM; Aghajanian C; Abu-Rustum NR; Ladanyi M; Ellenson LH; Weigelt B; Soslow RA
Clin Cancer Res; 2021 May; 27(9):2613-2623. PubMed ID: 33602681
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10. The Roles of spop in DNA Damage Response and DNA Replication.
Maekawa M; Higashiyama S
Int J Mol Sci; 2020 Oct; 21(19):. PubMed ID: 33023230
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11. Structural Insights into BET Client Recognition of Endometrial and Prostate cancer-Associated spop Mutants.
Ostertag MS; Hutwelker W; Plettenburg O; Sattler M; Popowicz GM
J Mol Biol; 2019 May; 431(11):2213-2221. PubMed ID: 31026449
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12. Clinical value screening, prognostic significance and key pathway identification of miR-204-5p in endometrial carcinoma: A study based on the cancer Genome Atlas (TCGA), and bioinformatics analysis.
Guo S; Yang J; Wu M; Xiao G
Pathol Res Pract; 2019 May; 215(5):1003-1011. PubMed ID: 30910254
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13. Targeted sequencing with a customized panel to assess histological typing in endometrial carcinoma.
Cuevas D; Valls J; Gatius S; Roman-Canal B; Estaran E; Dorca E; Santacana M; Vaquero M; Eritja N; Velasco A; Matias-Guiu X
Virchows Arch; 2019 May; 474(5):585-598. PubMed ID: 30710169
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14. Opposing effects of cancer-type-specific spop mutants on BET protein degradation and sensitivity to BET inhibitors.
Janouskova H; El Tekle G; Bellini E; Udeshi ND; Rinaldi A; Ulbricht A; Bernasocchi T; Civenni G; Losa M; Svinkina T; Bielski CM; Kryukov GV; Cascione L; Napoli S; Enchev RI; Mutch DG; Carney ME; Berchuck A; Winterhoff BJN; Broaddus RR; Schraml P; Moch H; Bertoni F; Catapano CV; Peter M; Carr SA; Garraway LA; Wild PJ; Theurillat JP
Nat Med; 2017 Sep; 23(9):1046-1054. PubMed ID: 28805821
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15. The genetic landscape of endometrial clear cell carcinomas.
DeLair DF; Burke KA; Selenica P; Lim RS; Scott SN; Middha S; Mohanty AS; Cheng DT; Berger MF; Soslow RA; Weigelt B
J Pathol; 2017 Oct; 243(2):230-241. PubMed ID: 28718916
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16. Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.
Le Gallo M; Rudd ML; Urick ME; Hansen NF; Zhang S; ; Lozy F; Sgroi DC; Vidal Bel A; Matias-Guiu X; Broaddus RR; Lu KH; Levine DA; Mutch DG; Goodfellow PJ; Salvesen HB; Mullikin JC; Bell DW
Cancer; 2017 Sep; 123(17):3261-3268. PubMed ID: 28485815
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17. Rates of colpopexy and colporrhaphy at the time of hysterectomy for prolapse.
Fairchild PS; Kamdar NS; Berger MB; Morgan DM
Am J Obstet Gynecol; 2016 Feb; 214(2):262.e1-262.e7. PubMed ID: 26366666
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18. Endometrial cancer-associated mutants of spop are defective in regulating estrogen receptor-α protein turnover.
Zhang P; Gao K; Jin X; Ma J; Peng J; Wumaier R; Tang Y; Zhang Y; An J; Yan Q; Dong Y; Huang H; Yu L; Wang C
Cell Death Dis; 2015 Mar; 6(3):e1687. PubMed ID: 25766326
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19. The emerging role of speckle-type POZ protein (spop) in cancer development.
Mani RS
Drug Discov Today; 2014 Sep; 19(9):1498-502. PubMed ID: 25058385
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20. Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.
Le Gallo M; O'Hara AJ; Rudd ML; Urick ME; Hansen NF; O'Neil NJ; Price JC; Zhang S; England BM; Godwin AK; Sgroi DC; ; Hieter P; Mullikin JC; Merino MJ; Bell DW
Nat Genet; 2012 Dec; 44(12):1310-5. PubMed ID: 23104009
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