BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Uterine cancer AND TSC2, FLJ43106, 7249, ENSG00000103197, LAM, tuberin, TSC4 AND Treatment
25 results:

  • 1. The Effect of a Myomectomy on Myoma-related Symptoms and Quality of Life: A Retrospective Cohort Study.
    Don EE; Mijatovic V; van Eekelen R; Hehenkamp WJK; Huirne JAF
    J Minim Invasive Gynecol; 2023 Nov; 30(11):897-904. PubMed ID: 37453499
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Tuberous sclerosis complex misdiagnosed as multiple metastases in a cervical cancer patient: case report and literature review.
    Ye T; Feng L; Peng M; Yuan S; Chen Y; Liu X; Chen J
    Ann Palliat Med; 2021 Oct; 10(10):11232-11238. PubMed ID: 34763482
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. tsc2-mutant uterine sarcomas with JAZF1-SUZ12 fusions demonstrate hybrid features of endometrial stromal sarcoma and PEComa and are responsive to mTOR inhibition.
    Chiang S; Vasudevaraja V; Serrano J; Stewart CJR; Oliva E; Momeni-Boroujeni A; Jungbluth AA; Da Cruz Paula A; da Silva EM; Weigelt B; Park KJ; Soslow RA; Murali R; Ellenson LH; Benayed R; Ladanyi M; Abu-Rustum NR; Dickson MA; Cohen S; Aghajanian C; Hensley ML; Lee CH; Snuderl M; Konner JA
    Mod Pathol; 2022 Jan; 35(1):117-127. PubMed ID: 34561551
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Phase II Clinical Trial of Everolimus in a Pan-cancer Cohort of Patients with mTOR Pathway Alterations.
    Adib E; Klonowska K; Giannikou K; Do KT; Pruitt-Thompson S; Bhushan K; Milstein MI; Hedglin J; Kargus KE; Sholl LM; Tsuji J; Hyman DM; Sisk A; Shapiro GI; Vargas HA; Harding JJ; Voss MH; Iyer G; Kwiatkowski DJ
    Clin Cancer Res; 2021 Jul; 27(14):3845-3853. PubMed ID: 33727259
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Neutrophil elastase from myeloid cells promotes tsc2-null tumor growth.
    Taya M; Garcia-Hernandez ML; Rangel-Moreno J; Minor B; Gibbons E; Hammes SR
    Endocr Relat Cancer; 2020 Apr; 27(4):261-274. PubMed ID: 32045362
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Familial Kidney cancer: Implications of New Syndromes and Molecular Insights.
    Carlo MI; Hakimi AA; Stewart GD; Bratslavsky G; Brugarolas J; Chen YB; Linehan WM; Maher ER; Merino MJ; Offit K; Reuter VE; Shuch B; Coleman JA
    Eur Urol; 2019 Dec; 76(6):754-764. PubMed ID: 31326218
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Comprehensive genomic profiling aids in treatment of a metastatic endometrial cancer.
    Dhami J; Hirshfield KM; Ganesan S; Hellmann M; Rojas V; Amorosa JK; Riedlinger GM; Zhong H; Ali SM; Pavlick D; Elvin JA; Rodriguez-Rodriguez L
    Cold Spring Harb Mol Case Stud; 2018 Apr; 4(2):. PubMed ID: 29588307
    [No Abstract]    [Full Text] [Related]  

  • 8. treatment of Advanced Malignant uterine Perivascular Epithelioid Cell Tumor with mTOR Inhibitors: Single-institution Experience and Review of the Literature.
    Starbuck KD; Drake RD; Budd GT; Rose PG
    Anticancer Res; 2016 Nov; 36(11):6161-6164. PubMed ID: 27793946
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2.
    Goldberg AA; Joung KB; Mansuri A; Kang Y; Echavarria R; Nikolajev L; Sun Y; Yu JJ; Laporte SA; Schwertani A; Kristof AS
    Oncotarget; 2016 Sep; 7(38):61152-61165. PubMed ID: 27458154
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Minireview: Lymphangioleiomyomatosis (lam): The "Other" Steroid-Sensitive cancer.
    Prizant H; Hammes SR
    Endocrinology; 2016 Sep; 157(9):3374-83. PubMed ID: 27409646
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Estrogen maintains myometrial tumors in a lymphangioleiomyomatosis model.
    Prizant H; Taya M; Lerman I; Light A; Sen A; Mitra S; Foster TH; Hammes SR
    Endocr Relat Cancer; 2016 Apr; 23(4):265-80. PubMed ID: 26880751
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
    Hu Z; Wang Y; Huang F; Chen R; Li C; Wang F; Goto J; Kwiatkowski DJ; Wdzieczak-Bakala J; Tu P; Liu J; Zha X; Zhang H
    J Biol Chem; 2015 Oct; 290(42):25756-65. PubMed ID: 26296882
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Effects of combining rapamycin and resveratrol on apoptosis and growth of tsc2-deficient xenograft tumors.
    Alayev A; Salamon RS; Sun Y; Schwartz NS; Li C; Yu JJ; Holz MK
    Am J Respir Cell Mol Biol; 2015 Nov; 53(5):637-46. PubMed ID: 25844891
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Progesterone and estradiol synergistically promote the lung metastasis of tuberin-deficient cells in a preclinical model of lymphangioleiomyomatosis.
    Sun Y; Zhang E; Lao T; Pereira AM; Li C; Xiong L; Morrison T; Haley KJ; Zhou X; Yu JJ
    Horm Cancer; 2014 Oct; 5(5):284-98. PubMed ID: 25069840
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.
    Peng H; Liu J; Sun Q; Chen R; Wang Y; Duan J; Li C; Li B; Jing Y; Chen X; Mao Q; Xu KF; Walker CL; Li J; Wang J; Zhang H
    Oncogene; 2013 Sep; 32(39):4702-11. PubMed ID: 23108404
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
    Tanwar PS; Kaneko-Tarui T; Zhang L; Tanaka Y; Crum CP; Teixeira JM
    PLoS Genet; 2012; 8(8):e1002906. PubMed ID: 22916036
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Anticancer property of Bryophyllum pinnata (lam.) Oken. leaf on human cervical cancer cells.
    Mahata S; Maru S; Shukla S; Pandey A; Mugesh G; Das BC; Bharti AC
    BMC Complement Altern Med; 2012 Mar; 12():15. PubMed ID: 22405256
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Favorable response to antigonadal therapy for a benign metastasizing leiomyoma.
    Taveira-DaSilva AM; Alford CE; Levens ED; Kotz HL; Moss J
    Obstet Gynecol; 2012 Feb; 119(2 Pt 2):438-442. PubMed ID: 22270431
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Prevalence of uterine leiomyomas in lymphangioleiomyomatosis.
    Taveira-Dasilva AM; Rabel A; Gochuico BR; Avila NA; Moss J
    Fertil Steril; 2011 Sep; 96(3):711-714.e1. PubMed ID: 21880281
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Loss of inhibitory insulin receptor substrate-1 phosphorylation is an early event in mammalian target of rapamycin-dependent endometrial hyperplasia and carcinoma.
    McCampbell AS; Harris HA; Crabtree JS; Winneker RC; Walker CL; Broaddus RR
    Cancer Prev Res (Phila); 2010 Mar; 3(3):290-300. PubMed ID: 20179297
    [TBL] [Abstract] [Full Text] [Related]  


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