These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Pseudomonas aeruginosa exoenzyme S is a biglutamic acid ADP-ribosyltransferase.
    Author: Radke J, Pederson KJ, Barbieri JT.
    Journal: Infect Immun; 1999 Mar; 67(3):1508-10. PubMed ID: 10024602.
    Abstract:
    Kinetic analysis of two mutations within Pseudomonas aeruginosa exoenzyme S (ExoS) showed that a E379D mutation inhibited expression of ADP-ribosyltransferase activity but had little effect on the expression of NAD glycohydrolase activity while a E381D mutation inhibited expression of both activities. These data identify ExoS as a biglutamic acid ADP-ribosyltransferase, where E381 is the catalytic residue and E379 contributes to the transfer of ADP-ribose to the target protein.
    [Abstract] [Full Text] [Related] [New Search]