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  • Title: Nuclease cleavage of chromatin at 100-nucleotide pair intervals.
    Author: Altenburger W, Hörz W, Zachau HG.
    Journal: Nature; 1976 Dec 09; 264(5586):517-22. PubMed ID: 1004586.
    Abstract:
    Digestion of mouse liver nuclei with DNase II leads to a novel cleavage pattern with a 100-nucleotide pair periodicity. From chromatin, this pattern or the standard 200-nucleotide pair repeat can be produced depending on the ionic conditions. The results are interpreted by assuming different conformational states of the nuclear material, including condensed and extended forms.
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