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  • Title: [Cardiopulmonary effects of two modes of mechanical ventilation in dogs with and without acute lung injury-comparison of pressure regulated biphasic airway presure ventilation and intermittent positive pressure ventilation].
    Author: Hong Q, Bai C, Song Y.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 1997 Aug; 20(4):218-21. PubMed ID: 10072806.
    Abstract:
    OBJECTIVE: To compare the cardiopulmonary effect of pressure regulated biphasic airway pressure (BiPAP) and intermittent positive pressure ventilation (IPPV). METHOD: Airway pressure, hemodynamics and blood gases were measured during the two ventilatory modalities with 0, 0.5, 1 kPa external end-expiratory pressure (EEP) in dogs with and without oleic acid-induced lung injury. RESULTS: No matter whether there is lung injury, airway pressure during BiPAP is lower compared with IPPV, but there is no difference in cardiac output. In dogs with lung injury, PaO2 during BiPAP is higher than that during IPPV. CONCLUSIONS: Compared with IPPV, BiPAP effected a decrease in airway pressure, and PaO2 was improved in dogs with lung injury, although the cardiac output was not increased.
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