These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Diabetes mellitus associated with the A3243G mutation of mitochondrial DNA. Apropos a case].
    Author: Biarnés J, Barrientos A, Ricart W, Nunes V, Fernández-Castañer M, Soler J.
    Journal: Med Clin (Barc); 1999 Jan 30; 112(3):99-101. PubMed ID: 10074618.
    Abstract:
    The mitochondrial A3243G mutation of the tRNA(Leu) has been described in pedigrees with maternally inherited diabetes mellitus and deafness. Ten diabetic patients with sensorineural deafness were studied. Polymerase chain reaction and enzyme restriction analysis with Apa I were performed. The mutation was found in heteroplasmy in only one patient (1/10). She was a 43-years-old woman with maternally inherited diabetes and deafness since she was 29. The association of sensorineural deafness and maternal inherited diabetes are the clues to suspect this subtype of diabetes.
    [Abstract] [Full Text] [Related] [New Search]