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  • Title: [Electrolyte studies in major abdominal surgery. I. Neuroleptanalgesia and Variations of the infusion scheme (author's transl)].
    Author: Finsterer U, Lühr HG, Götz E.
    Journal: Anaesthesist; 1976 Dec; 25(12):563-71. PubMed ID: 1008247.
    Abstract:
    In two groups of 30 patients each who had undergone abdominal surgery under NLA (mean anaesthesia time 4h) we found a small but significant reduction in the serum potassium level after 45 min of anaesthesia. Throughout anaesthesia we found a significant reduction of potassium content of red cells, serum sodium and base excess. Potassium balance shows that under anaesthesia and operation potassium moves out of the extracellular space and the red cells into other compartments. At the same time about 75 per cent of infused sodium and water is retained with a positive correlation between the quantities of sodium infused and retained. A modification of the infusion regimen by substituting glucose solution with distilled water and Ringer lactate with normal saline and 5 mval/l KCI only results in a change in blood glucose and serum sodium.
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