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  • Title: [Familial granulomatous disease: histopathological and histogentic data].
    Author: Vilde F, Nezelof C.
    Journal: Ann Anat Pathol (Paris); 1976; 21(1):59-74. PubMed ID: 1008319.
    Abstract:
    The lesions seen in chronic familial granulomatosis are variable and seen in varied combinations: granulomas, often disseminated, pseudotuberculous lesions, histiocytes with a high content in lipofuscins seen in the liver, lymph nodes, spleen and lungs in particular. These lesions may be explained at least in part by a congenital defect in leucocytes, which is peculiar to this hereditary disease, and which concernes bactericidal functions.
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