These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Home delivery of heat-stable vaccines in Indonesia: outreach immunization with a prefilled, single-use injection device.
    Author: Sutanto A, Suarnawa IM, Nelson CM, Stewart T, Soewarso TI.
    Journal: Bull World Health Organ; 1999; 77(2):119-26. PubMed ID: 10083709.
    Abstract:
    Extending immunization coverage to underserved populations will require innovative immunization strategies. This study evaluated one such strategy: the use of a prefilled, single-use injection device for outreach immunization by village midwives. The device, UniJect, is designed to prevent refilling or reuse. Stored at ambient temperatures for up to 1 month in midwives' homes, vaccine-filled UniJect devices were immediately available for outreach. Between July 1995 and April 1996, 110 midwives on the Indonesia islands of Lombok and Bali visited the homes of newborn infants to deliver hepatitis B vaccine to the infants and tetanus toxoid to their mothers. Observations and interviews showed that the midwives used the device properly and safely to administer approximately 10,000 sterile injections in home settings. There were no problems with excessive heat exposure during the storage or delivery of vaccine. Injection recipients and midwives expressed a strong preference for the UniJect device over a standard syringe. Use of the prefilled device outside the cold chain simplified the logistics and facilitated the speed and efficiency of home visits, while the single-dose format minimized vaccine wastage. Recent studies have found that up to 30% of injections given for immunization are not sterile. Disposable syringes are reused and reusable syringes are often improperly sterilized. Findings are presented from an evaluation of the use of a prefilled, single-use injection device for outreach immunization by village midwives. Such devices can reduce the transmission of bloodborne pathogens and diseases, and reduce vaccine wastage associated with multi-dose vials. The device evaluated, UniJect, is designed to prevent refilling or reuse. Stored at ambient temperatures for up to 1 month in midwives' homes, vaccine-filled UniJect devices were immediately available for use. Between July 1995 and April 1996, 110 midwives on the Indonesian islands of Lombok and Bali visited the homes of newborn infants to deliver hepatitis B vaccine to infants and tetanus toxoid to their mothers. Observations and interviews found that the midwives safely and properly used the device to administer approximately 10,000 sterile injections in home settings. No problems were experienced with excessive heat exposure during the storage or delivery of vaccine. Injection recipients and midwives strongly preferred the UniJect device over a standard syringe. Furthermore, use of the prefilled device outside of the cold chain simplified the logistics and facilitated the speed and efficiency of home visits, while the single-dose format minimized vaccine wastage.
    [Abstract] [Full Text] [Related] [New Search]