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  • Title: Bacterial growth in space flight: logistic growth curve parameters for Escherichia coli and Bacillus subtilis.
    Author: Kacena MA, Merrell GA, Manfredi B, Smith EE, Klaus DM, Todd P.
    Journal: Appl Microbiol Biotechnol; 1999 Feb; 51(2):229-34. PubMed ID: 10091330.
    Abstract:
    Previous investigations have reported that bacterial suspension cultures grow to higher stationary concentrations in space flight than on Earth; however, none of these investigations included extensive ground controls under varied inertial conditions. This study includes extensive controls and cell-growth data taken at several times during lag phase, log phase, and stationary phase of Escherichia coli and Bacillus subtilis. The Marquardt-Levenberg, least-squares fitting algorithm was used to calculate kinetic growth parameters from the logistic bacterial growth equations for space-flight and control growth curves. Space-flight cultures grew to higher stationary-phase concentrations and had shorter lag-phase durations. Also, evidence was found for increased exponential growth rate in space.
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