These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Technetium-99m complexes of polydentate amine-pyrrole and amine-thiophene ligands.
    Author: Pillai MR, Samuel G, Banerjee S, Mathew B, Sarma HD, Jurisson S.
    Journal: Nucl Med Biol; 1999 Jan; 26(1):69-77. PubMed ID: 10096504.
    Abstract:
    Novel polydentate amine-pyrrole and amine-thiophene ligands were synthesized and characterized by 1H and 13C NMR spectroscopy. Radiochemical studies with 99mTc were carried out at 0.1-100 microM of technetium. Complexation yields were estimated from thin layer chromatography (TLC), paper electrophoresis, and solvent extraction studies. The 99mTc complexes formed were found to be neutral and lipophilic. Complexes with the corresponding imine-ligands were formed in lower yields. Biodistribution studies of the 99mTc complexes of these ligands showed no significant uptake in brain or heart, and the clearance was mainly through the hepatobiliary system.
    [Abstract] [Full Text] [Related] [New Search]