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  • Title: Field study on the insecticidal efficacy of Advantage against natural infestations of dogs with lice.
    Author: Hanssen I, Mencke N, Asskildt H, Ewald-Hamm D, Dorn H.
    Journal: Parasitol Res; 1999 Apr; 85(4):347-8. PubMed ID: 10099020.
    Abstract:
    A clinical field trial was performed to evaluate the efficacy of imidacloprid, the active ingredient of Advantage 10% Spot-On, against natural lice infestations on dogs. Imidacloprid was highly effective against both sucking (Linognathus setosus) and biting (Trichodectes canis) lice over the 6-week period of the trial. The duration of efficacy exceeded the egg-to-imago development period of both lice. Signs of remission of dermatitis and alopecia became visible to the pet owners at 2 weeks after treatment. The constant pruritus caused by the lice was seen for up to 2-4 weeks after treatment even in the absence of lice.
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