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  • Title: [Coronary artery spasm induced by the somministration of ergonovine maleate in subjects with spontaneous angina (author's transl)].
    Author: Specchia G, Angoli L, De Servi S, Mussini A, Bramucci E, Marinoni G, Ray M, Montemartini C, Di Guglielmo L, Bobba L.
    Journal: G Ital Cardiol; 1976; 6(7):1177-83. PubMed ID: 1010229.
    Abstract:
    In 6 patients affected by spontaneous angina with S-T elevation and coronariographic findings of obstruction, intravenous administration of ergonovine maleate determined the same clinical and ECG patterns of spontaneous episodes. The coronary arteriography during pain showed a marked spasm with occlusion of a large coronary vessel in four patients. In 2 patients with atypical chest pain and normal coronariogram, E.M. did not induce pain, ECG abnormality or coronariographic alterations. The role of spasm in spontaneous angina is discussed.
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