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  • Title: A potent polyamine analog, spermindiol.
    Author: Yanagawa H, Ogawa Y, Egami F.
    Journal: J Biochem; 1976 Oct; 80(4):891-3. PubMed ID: 1010853.
    Abstract:
    The effects of spermine, putrescine, and spermindiol on different nucleases were investigated. A highly active spermine analog, spermindiol, was synthesized, which markedly enhanced DNA hydrolysis by staphylococcal nuclease and spleen DNase II [EC 3.1.4.6] and RNA degradation by staphylococcal nuclease and pancreatic RNase A [EC 3.1.4.22]. Spermindiol also increased the melting temperature of calf thymus DNA.
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