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  • Title: [Significance of endometrial cells in cervical smears in relation to the use of intrauterine devices].
    Author: Alcaino I, Bierschwale M.
    Journal: Rev Chil Obstet Ginecol; 1976; 41(2):95-8. PubMed ID: 1013438.
    Abstract:
    The presence of endometrial cells in cervical smears can be significant depending on the age of the woman, in which phase of the menstrual cycle they appear, or if there is a mechanical device (IUD) present which might cause their appearance. Cervical smears of 77 premanopausal women were studied. 53 used IUDs and 24 did not. The control group was made up of womwen for whom 353 consecutive smears were without endometrial cells. The total number of women was divided into 3 groups by age: 20-29, 30-39, and 40-45 years. The cycle was divided into 3 phases: the menstrual phase (Days 1-8), the proliferative phase (Days 9-14), the secretory phase (Days 15-28). A diagnostic study was done to differentiate the type of endometrial cells for those with and without IUDs. There was no difference according to age distribution of the group studied and the control group. The women using the IUD could exfoliate endometrial cells in any phase, although with greater frequency in the 1st 2 phases. The quantity of cells lost in the 1st phase was similar for IUD users and nonusers. Finding cells in the 2nd phase when there was no IUD to provoke them was significant. These women were older and the cells were glandular. It suggested hyperplasia or neoplasms. There seemed to be no significant difference between the percentages of IUD users and those without IUDs exfoliating endometrial cells. The former had 47.2% in the 1st phase, 30.2% in the 2nd, and 22.6% in the 3rd. The latter had 45.8, 29.2, and 25.0%, respectively.
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