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  • Title: Electrocardiographic studies during hypotensive anaesthesia using sodium nitroprusside.
    Author: Simpson P, Bellamy D, Cole P.
    Journal: Anaesthesia; 1976 Nov; 31(9):1172-8. PubMed ID: 1015600.
    Abstract:
    Multiple lead electrocardiographic recordings from 20 patients were studied before, during and after a period of induced hypotension with sodium nitroprusside. Although small changes in ST segment and T wave were observed in 9 patients, none of these persisted into the postoperative period. Other significant changes were confined to a temporary disturbances of cardiac rhythm in 2 patients, both of whom spontaneously reverted to sinus rhythm during the anaesthetic. Our findings indicate that there are no permanent ischaemic myocardial changes associated with induced hypotension using sodium nitroprusside.
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