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  • Title: [Comparative study of the level of mitotic activity and duration of mitosis over a 24 hour period in mouse tumors and normal tissue].
    Author: Berezkin MV.
    Journal: Biull Eksp Biol Med; 1976; 82(11):1363-5. PubMed ID: 1016722.
    Abstract:
    Circadian rhythm of cell division in the forestomack epithelium proved to be largely similar to that in the transplantable (continuous) carcinoma of the forestomack; the duration of mitosis in these tissues changed in the course of 24-hours. The mean 24-hour mitotic activity in the tumour was double that in the forestomack contrary to this, colchamine (colcemide) accumulated in the course of the 24-hours 121.1% mitoses in the forestomack and 83.8% mitoses in the carcinoma. A greater number of mitoses in the tumour with the usual count is attributed to the fact that the mean 24-hour duration of mitosis of the remen carcinoma was 2.7 greater than in the epithelium of the forestomack.
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